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Effects of radiofrequency ablation and complete endoscopic resection are equal in dysplastic Barrett's esophagus

According to a new systematic review article, radiofrequency ablation and complete endoscopic resection are equally effective in the short-term treatment of dysplastic Barrett's esophagus, but adverse event rates are higher with complete endoscopic resection.

22 May 2014

Phase 3 data of VIVACITO study evaluating effect of T+O FDC in COPD presented at ATS conference

Boehringer Ingelheim today presented results of the VIVACITO® (NCT01559116) study, the first Phase 3 data to be reported from the TOviTO® clinical trial program, evaluating the effect of the fixed-dose combination of tiotropium and olodaterol (T+O FDC) delivered via the Respimat® inhaler on lung function in people with chronic obstructive pulmonary disease (COPD).

22 May 2014

Researchers discover key proteins involved in DNA repair gone awry

Accumulation of DNA damage can cause aggressive forms of cancer and accelerated aging, so the body's DNA repair mechanisms are normally key to good health. However, in some diseases the DNA repair machinery can become harmful.

22 May 2014

Double mastectomies are unnecessary in women with breast cancer, says study

About 70 percent of women who have both breasts removed following a breast cancer diagnosis do so despite a very low risk of facing cancer in the healthy breast, new research from the University of Michigan Comprehensive Cancer Center finds

22 May 2014

Dolutegravir drug offers added benefit in HIV patients

Dolutegravir has been approved since January 2014 in combination with other antiretroviral drugs for the treatment of human immunodeficiency virus (HIV) infected adults and adolescents above 12 years of age.

22 May 2014

Physiotherapy for hip osteoarthritis questioned

Hip osteoarthritis is a prevalent and costly chronic musculoskeletal condition. Clinical guidelines recommend physiotherapy as treatment, although its effectiveness has never been proven.

22 May 2014

Erlotinib, gefitinib have similar efficacy in NSCLC patients with EGFR mutation

Disease progression-free survival is similar for patients with non-small-cell lung cancer and epidermal growth factor receptor mutations whether they receive erlotinib or gefitinib, show the results of a South Korean study.

21 May 2014

Cholesterol plays vital role in cell mobility and tissue invasion

University of Barcelona's researchers led by Professor Carles Enrich, from the Department of Cell Biology, Immunology and Neurosciences of the Faculty of Medicine at the University of Barcelona and CELLEX Biomedical Research Centre of IDIBAPS, have found that cholesterol plays a key role in cell mobility and tissue invasion.

21 May 2014

Telemedicine in action: an interview with Ian Jackson, Managing Director, Imerja

Telemedicine is a term used to describe the use of information technology in delivering curative or clinical care healthcare, allowing medical specialists to communicate with patients and other medical staff, regardless of their physical location.

21 May 2014

Mayo Clinic study provides key insights into aggressive form of pancreatic cancer

Mayo Clinic researchers have discovered an enzyme they say is tightly linked to how aggressive pancreatic cancer will be in a patient.

21 May 2014

New program improves quality of care for people with cognitive impairment in low cost

The patient and caregiver-centered Aging Brain Care program, developed by researchers at the Regenstrief Institute and the Indiana University Center for Aging Research, is attracting nationwide interest for its ability to improve health outcomes and quality of care for those with cognitive impairment while dramatically lowering costs to patients and health care systems.

21 May 2014

Genprex initiates Phase II clinical trial of Oncoprex for late-stage lung cancer patients

Genprex, Inc. announced today that it has enrolled the first patient in a clinical trial evaluating its lead product candidate Oncoprex in combination with erlotinib (Tarceva) for late-stage lung cancer patients.

21 May 2014

Nationwide Children's Hospital offers Meta-iodobenzylguanidine therapy for neuroblastoma

Meta-iodobenzylguanidine (MIBG) therapy is now offered by Hematology/Oncology/Blood and Marrow Transplant at Nationwide Children's Hospital. Patients with neuroblastoma who qualify for treatment with MIBG therapy can be treated in this new facility, with round-the-clock supervision by specially trained staff through video and audio monitoring.

21 May 2014

Research provides key insights into most aggressive form of pancreatic cancer

Mayo Clinic researchers have discovered an enzyme they say is tightly linked to how aggressive pancreatic cancer will be in a patient.

21 May 2014

69% of healthy American adults are infected with 109 strains of human papillomavirus

In what is believed to be the largest and most detailed genetic analysis of its kind, researchers at NYU Langone Medical Center and elsewhere have concluded that 69 percent of healthy American adults are infected with one or more of 109 strains of human papillomavirus (HPV).

21 May 2014

New compound restores learning, memory and other symptoms of AD in mice

A molecular compound developed by Saint Louis University scientists restored learning, memory and appropriate behavior in a mouse model of Alzheimer's disease, according to findings in the May issue of the Journal of Alzheimer's Disease.

21 May 2014

FDA approves Takeda's Entyvio for severe active ulcerative colitis and Crohn's disease

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals U.S.A., Inc., has announced that the United States (U.S.) Food and Drug Administration (FDA) simultaneously approved a new biologic therapy, Entyvio™ (vedolizumab), for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn's disease (CD).

21 May 2014

Space Station science: Microgravity on human thyroid carcinoma cells

The multi-national efforts that go into research aboard the International Space Station show that working together can yield results with universal benefits.

21 May 2014

Pemetrexed plus erlotinib shows benefits in NSCLC

Pemetrexed used in combination with erlotinib may have clinical advantage over single-agent pemetrexed when used as a second-line treatment in patients with non-squamous non-small-cell lung cancer, researchers report.

20 May 2014

The future of high throughput screening: an interview with Mark Wigglesworth, Director High Throughput Screening, AstraZeneca

Quoting Mike Snowden (VP & Head of Discovery Sciences, AstraZeneca), “it’s where biology meets chemistry”. It’s where for the first time a target protein can be probed for novel molecules that modulate its function, of course we want to do this to prove a hypothesis that these proteins are drug targets with the potential to deliver innovative medicines.

20 May 2014

Therapy News and Research

Effects of radiofrequency ablation and complete endoscopic resection are equal in dysplastic Barrett's esophagus

Phase 3 data of VIVACITO study evaluating effect of T+O FDC in COPD presented at ATS conference

Researchers discover key proteins involved in DNA repair gone awry

Double mastectomies are unnecessary in women with breast cancer, says study

Dolutegravir drug offers added benefit in HIV patients

Physiotherapy for hip osteoarthritis questioned

Erlotinib, gefitinib have similar efficacy in NSCLC patients with EGFR mutation

Cholesterol plays vital role in cell mobility and tissue invasion

Telemedicine in action: an interview with Ian Jackson, Managing Director, Imerja

Mayo Clinic study provides key insights into aggressive form of pancreatic cancer

New program improves quality of care for people with cognitive impairment in low cost

Genprex initiates Phase II clinical trial of Oncoprex for late-stage lung cancer patients

Nationwide Children's Hospital offers Meta-iodobenzylguanidine therapy for neuroblastoma

Research provides key insights into most aggressive form of pancreatic cancer

69% of healthy American adults are infected with 109 strains of human papillomavirus

New compound restores learning, memory and other symptoms of AD in mice

FDA approves Takeda's Entyvio for severe active ulcerative colitis and Crohn's disease

Space Station science: Microgravity on human thyroid carcinoma cells

Pemetrexed plus erlotinib shows benefits in NSCLC

The future of high throughput screening: an interview with Mark Wigglesworth, Director High Throughput Screening, AstraZeneca

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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