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New integrated gene logic-chips could have great value in medical care

Gene expression is a fundamental of life, where each cell switches on and off specific genes. Thus, an autonomous device that could control the on-off switching would have great value in medical care.

20 Aug 2018

Study reveals how socioeconomic status affects racial, ethnic disparities in childhood cancer survival

A new study provides insights into the degree to which socioeconomic status explains racial and ethnic disparities in childhood cancer survival.

20 Aug 2018

Common antidepressant restores significant degree of lost plasticity to aging brain cells in mice

A new study provides fresh evidence that the decline in the capacity of brain cells to change, called "plasticity," rather than a decline in total cell number may underlie some of the sensory and cognitive declines associated with normal brain aging.

20 Aug 2018

Scientists introduce microfluidics-based chip for manipulation and analysis of single cells

A few little cells that are different from the rest can have a big effect. For example, individual cancer cells may be resistant to a specific chemotherapy--causing a relapse in a patient who would otherwise be cured. In the journal Angewandte Chemie, scientists have now introduced a microfluidics-based chip for the manipulation and subsequent nucleic-acid analysis of individual cells.

17 Aug 2018

New drug- free, nanotechnology-based method detects and treats oral plaque

When the good and bad bacteria in our mouth become imbalanced, the bad bacteria form a biofilm (aka plaque), which can cause cavities, and if left untreated over time, can lead to cardiovascular and other inflammatory diseases like diabetes and bacterial pneumonia.

17 Aug 2018

Biomarker predicts kidney cancer risk years before diagnosis

Scientists have identified a blood biomarker that could be used to predict the onset of renal cell carcinoma (RCC) years before the disease is diagnosed.

17 Aug 2018

PolyU researchers design new self-fitting scaffold to induce bone regeneration

Researchers from The Hong Kong Polytechnic University have designed and fabricated a high performing self-fitting bone scaffold by combining a shape memory foam and hydroxyapatite (the principal mineral component of bone tissue).

17 Aug 2018

Researchers develop new approach to study how tuberculosis infects people

Tuberculosis is one of the top 10 causes of death worldwide. Nearly 2 million people die every year from this infectious disease, and an estimated 2 billion people are chronically infected.

17 Aug 2018

New CRISPR technology may help eliminate mutated gene sequence

In a new study in cells, University of Illinois researchers have adapted CRISPR gene-editing technology to cause the cell's internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building.

17 Aug 2018

Blood biomarker could help predict kidney cancer up to five years prior to diagnosis

Every year, more than 330,000 people are diagnosed with kidney cancer worldwide. More than 80 percent of those new cases are renal cell carcinomas.

17 Aug 2018

CartiHeal and LSU Health successfully enroll first two patients in Agili-C IDE pivotal study

CartiHeal, developer of Agili-C, a proprietary implant for the treatment of joint surface lesions, and two LSU Health New Orleans orthopedic surgeons announced today the successful enrollment of the first two US patients in the Agili-C IDE pivotal study.

17 Aug 2018

NUS study discovers a bidirectional regulator and shines light on A-to-I RNA editing in cancer cells

An in-depth study on the regulation of adenosine-to-inosine (A-to-I) RNA editing by researchers from the Cancer Science Institute of Singapore at the National University of Singapore found that a protein, known as DHX9, acts as a bidirectional regulator of the molecular process which is linked to various types of cancer such as esophageal cancer.

17 Aug 2018

New project to combat DMD-related fibrosis receives major funding boost

Duchenne muscular dystrophy is one of the most common congenital diseases in the world, affecting one in 3,500 Canadian males. DMD is caused by mutations in the dystrophin gene that results in progressive muscle degeneration and there are currently no effective treatments for DMD.

17 Aug 2018

Researchers uncover surprising new role for inhibition in the cerebellum

Almost everyone is familiar with the unique mixture of surprise and confusion that occurs after making a mistake during an everyday movement.

17 Aug 2018

Brief exposures to stressors can be beneficial to cells, shows study

We've all heard the expression: "what doesn't kill you makes you stronger." Now, research led by a Salk Institute scientist suggests why, at a cellular level, this might be true.

17 Aug 2018

Researchers describe link between poor oocyte development and oxidative stress in obese mice

Excessive body fat is associated with negative effects on female fertility and pregnancy. In mice, maternal obesity impairs proper development of egg precursor cells called oocytes.

17 Aug 2018

Lowering pH inside tumor cells can slow down spread of cancer

A new study focusing on the environment inside cancer cells may lead to new targeted treatment strategies.

17 Aug 2018

Researchers describe promising strategy to remove melanoma's most powerful defenses

Immunotherapies use the immune system to fight cancer. But cancers like melanoma have found ways to turn off the immune system, allowing them to resist treatments and often leading to recurrence.

16 Aug 2018

Discovery may help broaden the scope of defenses against HPV

Yale Cancer Center scientists have filled in a key gap in understanding the unusual route by which the Human papillomavirus infects cells.

16 Aug 2018

Research uncovers miscarriage cause, identifies potential targets for treatment

Tragic miscarriages for a couple have led to a discovery with potentially broad implications for future disease treatments, according to a team of researchers at the University of North Carolina School of Medicine. They identified a previously undiscovered gene mutation underlying hydrops fetalis – a fatal condition to fetuses due to fluid buildup in the space between organs.

16 Aug 2018

B Cell News and Research

New integrated gene logic-chips could have great value in medical care

Study reveals how socioeconomic status affects racial, ethnic disparities in childhood cancer survival

Common antidepressant restores significant degree of lost plasticity to aging brain cells in mice

Scientists introduce microfluidics-based chip for manipulation and analysis of single cells

New drug- free, nanotechnology-based method detects and treats oral plaque

Biomarker predicts kidney cancer risk years before diagnosis

PolyU researchers design new self-fitting scaffold to induce bone regeneration

Researchers develop new approach to study how tuberculosis infects people

New CRISPR technology may help eliminate mutated gene sequence

Blood biomarker could help predict kidney cancer up to five years prior to diagnosis

CartiHeal and LSU Health successfully enroll first two patients in Agili-C IDE pivotal study

NUS study discovers a bidirectional regulator and shines light on A-to-I RNA editing in cancer cells

New project to combat DMD-related fibrosis receives major funding boost

Researchers uncover surprising new role for inhibition in the cerebellum

Brief exposures to stressors can be beneficial to cells, shows study

Researchers describe link between poor oocyte development and oxidative stress in obese mice

Lowering pH inside tumor cells can slow down spread of cancer

Researchers describe promising strategy to remove melanoma's most powerful defenses

Discovery may help broaden the scope of defenses against HPV

Research uncovers miscarriage cause, identifies potential targets for treatment

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