Therapy News and Research

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Autoimmune epilepsy diagnostics: an interview with Dr. Joseph J. Higgins, Medical Director, Neurology, Athena Diagnostics, a business of Quest Diagnostics

Epilepsy is a group of neurological disorders often characterized by seizures and cognitive impairment due to electrical disturbances in the brain.

From Quest Diagnostics 14 May 2014

Isis Pharmaceuticals reports positive data from ISIS-GCGRRx Phase 2 study in patients with type 2 diabetes

Isis Pharmaceuticals, Inc. announced today positive data from a Phase 2 study of ISIS-GCGRRx in patients with type 2 diabetes uncontrolled on stable metformin therapy.

14 May 2014

Researchers develop new high-tech device for transferring DNA into cells

The ability to transfer a gene or DNA sequence from one animal into the genome of another plays a critical role in a wide range of medical research-including cancer, Alzheimer's disease, and diabetes.

14 May 2014

Nimotuzumab enhances chemo-radiosensitivity by promoting autophagic cell death in ESCC cells

A study which will be published in the May 2014 issue of Experimental Biology and Medicine was aimed at determining whether an EGFR-targeted therapy combined with chemo-radiotherapy can improve local tumor control effectively, compared to cytotoxic agents or irradiation alone.

14 May 2014

MedImmune to present Phase IIb asthma data on benralizumab and tralokinumab at ATS conference

AstraZeneca today announced that MedImmune, its global biologics research and development arm, will present Phase IIb data on two novel investigational molecules – benralizumab and tralokinumab – at the upcoming American Thoracic Society 2014 International Conference being held in San Diego, California, 16-21 May.

14 May 2014

Intensive insulin treatment improves survival for diabetic heart attack patients

Long-term follow-up of the DIGAMI 1 trial – a landmark study of type 2 diabetes in Sweden – shows that intensive insulin treatment prolonged life by more than 2 years in patients with diabetes after a heart attack, compared with standard treatment for diabetes, reports Dr Viveca Ritsinger from the Unit of Cardiology of the Department of Medicine, Karolinska Institute, Stockholm, Sweden and colleagues in The Lancet Diabetes & Endocrinology.

14 May 2014

Minimally invasive TAVR procedure saves more lives than open-heart surgery, shows study

For the first time, a minimally invasive transcatheter valve - tested by Baylor Research Institute in Dallas (BRI) - has been shown to save more lives than open-heart surgery, according to new research revealed at the American College of Cardiology's 2014 Scientific Sessions and published in The New England Journal of Medicine.

From Medtronic 14 May 2014

CNS stimulant no more effective than placebo for alleviating lung cancer fatigue

Patients with advanced non-small-cell lung cancer who received the central nervous system stimulant modafinil reported no greater reduction in fatigue than patients given placebo, show study results.

13 May 2014

Scientists find new drug that improves effectiveness of radiotherapy in stopping tumor growth

Scientists from The University of Manchester - part of the Manchester Cancer Research Centre - have demonstrated the potential of a drug to improve the effectiveness of radiotherapy in stopping tumour growth.

13 May 2014

Amakem commences Phase 2 dose-ranging study of AMA0076 drug for treatment of glaucoma

Amakem Therapeutics, a clinical stage ophthalmology company, today announced that first patients have commenced treatment in a Phase 2 dose-ranging study of its lead drug candidate, AMA0076 for the treatment of glaucoma.

13 May 2014

Johns Hopkins scientists identify genetic marker associated with development of obsessive-compulsive disorder

A group of researchers led by Johns Hopkins scientists say they have identified a genetic marker that may be associated with the development of obsessive-compulsive disorder (OCD), whose causes and mechanisms are among the least understood among mental illnesses.

13 May 2014

Researchers identify target molecules for development of new allergy drugs

Researchers have identified several target molecules which are suitable for the development of new allergy drugs. The Journal of Allergy and Clinical Immunology, the most prestigious journal in the field of allergology, has recently published an extensive review article on the prospects of drug therapy for allergy. Completed in a large-scale EU project, the lead author of the review article is Professor Ilkka Harvima of the University of Eastern Finland and Kuopio University Hospital.

13 May 2014

Study reveals 70% of patients with diabetic retinopathy will develop macular edema

In Mexico, at least 14 million people have developed macular edema due to diabetes (DME), which like retinopathy affects central vision and can lead to blindness if not treated early .

13 May 2014

University of Chicago receives $3.9M award to serve as Lead Academic Participating Site for NCTN

A team from the University of Chicago Medicine Comprehensive Cancer Center has received a five-year, $3.9-million award from the National Cancer Institute to serve as a Lead Academic Participating Site for the newly created National Clinical Trials Network (NCTN).

13 May 2014

Researchers use molecular diagnostic methods to detect cancer

The ABC Medical Center, located in Mexico City, implemented various molecular diagnostic methods that can detect the genetic alterations in several types of cancer, so they can select a personalized therapy for each patient and direct it against the mutated genes that cause disease.

13 May 2014

Researchers identify several target molecules suitable for development of new allergy drugs

13 May 2014

Treating older men with early-stage prostate cancer does not help live longer

Treating older men with early-stage prostate cancer who also have other serious underlying health problems with aggressive therapies such as surgery or radiation therapy does not help them live longer and, in fact, can be detrimental, according to a study by UCLA researchers.

13 May 2014

2 genes work together to drive most lethal forms of prostate cancer

Two genes work together to drive the most lethal forms of prostate cancer, according to new research from the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center (CUMC).

13 May 2014

Abeona Therapeutics obtains FDA Orphan Drug Designations for Sanfilippo Syndrome therapies

Abeona Therapeutics, a start-up company created around intellectual property licensed from Nationwide Children's Hospital to develop treatments for Sanfilippo Syndrome Types A and B, has been granted Orphan Drug Designations for its lead investigational therapies by the U.S. Food and Drug Administration Office of Orphan Products Development.

12 May 2014

Esaote gets FDA clearance to market Virtual Navigator fusion imaging technology for ultrasound

Esaote North America announced today that it has received FDA clearance to market and sell its Virtual Navigator fusion imaging technology for ultrasound.

12 May 2014

Therapy News and Research

Autoimmune epilepsy diagnostics: an interview with Dr. Joseph J. Higgins, Medical Director, Neurology, Athena Diagnostics, a business of Quest Diagnostics

Isis Pharmaceuticals reports positive data from ISIS-GCGRRx Phase 2 study in patients with type 2 diabetes

Researchers develop new high-tech device for transferring DNA into cells

Nimotuzumab enhances chemo-radiosensitivity by promoting autophagic cell death in ESCC cells

MedImmune to present Phase IIb asthma data on benralizumab and tralokinumab at ATS conference

Intensive insulin treatment improves survival for diabetic heart attack patients

Minimally invasive TAVR procedure saves more lives than open-heart surgery, shows study

CNS stimulant no more effective than placebo for alleviating lung cancer fatigue

Scientists find new drug that improves effectiveness of radiotherapy in stopping tumor growth

Amakem commences Phase 2 dose-ranging study of AMA0076 drug for treatment of glaucoma

Johns Hopkins scientists identify genetic marker associated with development of obsessive-compulsive disorder

Researchers identify target molecules for development of new allergy drugs

Study reveals 70% of patients with diabetic retinopathy will develop macular edema

University of Chicago receives $3.9M award to serve as Lead Academic Participating Site for NCTN

Researchers use molecular diagnostic methods to detect cancer

Researchers identify several target molecules suitable for development of new allergy drugs

Treating older men with early-stage prostate cancer does not help live longer

2 genes work together to drive most lethal forms of prostate cancer

Abeona Therapeutics obtains FDA Orphan Drug Designations for Sanfilippo Syndrome therapies

Esaote gets FDA clearance to market Virtual Navigator fusion imaging technology for ultrasound

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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