Fibrosis News and Research

RSS

Fibrosis is the growth of fibrous tissue.

Patients with COPD show improvements in lung function with olodaterol

Data from the olodaterol Phase 3 clinical program, presented for the first time at the European Respiratory Society (ERS) Annual Congress 2013 in Barcelona, showed the addition of olodaterol 5 and 10 µg delivered once daily via the Respimat® inhaler provided improvements in lung function in patients with moderate to very severe chronic obstructive pulmonary disease (COPD).

10 Sep 2013

Parasites could be potential key to treating autoimmune diseases

There is a new weapon in the fight against autoimmune diseases such as Type 1 diabetes, rheumatoid arthritis, Crohn's disease and lupus, the common trait of which is an immune system that attacks its own organs and tissues.

10 Sep 2013

New study reveals damaging effects of road-side pollution in people with bronchiectasis

Living close to a busy road is associated with a higher risk of death in people with bronchiectasis.

10 Sep 2013

Head and neck cancer patients receiving radiation benefit from swallowing exercises

A study at UCLA's Jonsson Comprehensive Cancer Center has found that head and neck cancer patients receiving radiation as part of their treatment were less likely to need a feeding tube or suffer unwanted side effects such as worsening of diet or narrowing of the throat passage if they performed a set of prescribed swallowing exercises - called a "swallow preservation protocol" - during therapy.

5 Sep 2013

FIBRO-TARGETS project aims to identify mechanisms involved in MIF, define therapeutic approaches

Unravelling the mechanisms of cardiac fibrosis will lead to the discovery of therapeutic target candidates for various cardiac diseases. FIBRO-TARGETS brings together eleven European expert teams from six different countries both from public research institutes and European biotechs.

5 Sep 2013

UNC study to explore technology use in screening newborns for genetic conditions

As the clinical use of genomic testing expands, the practical and ethical considerations of using the technology to screen newborns for genetic conditions will be the focus of a new study undertaken at the University of North Carolina.

5 Sep 2013

Women are 25% less likely to die post TAVI than men, says doctor

Dr Sherif said: "Earlier studies on the impact of gender on outcome after transcatheter aortic valve implantation (TAVI) have had conflicting results. A Canadian study reported in 641 consecutive patients that female sex is associated with a better long-term and short-term survival after TAVI.1 An Italian study of 305 high risk patients found no gender differences in composite safety and efficacy endpoints at 30 days and one year after TAVI."2

2 Sep 2013

DE-MRI before ablation can stage atrial fibrosis and help predict success treatment

In patients with atrial fibrillation, delayed enhancement magnetic resonance imaging (DE-MRI) performed before ablative treatment can stage the degree of damaged heart tissue (atrial fibrosis) and help predict whether treatment will be successful or not, according to results of Delayed Enhancement - MRI determinant of successful Catheter Ablation of Atrial Fibrillation (DECAAF) trial.

2 Sep 2013

Head, neck cancer patients receiving radiation complied with SPP likely to suffer side effects

A study from UCLA's Jonsson Comprehensive Cancer Center (JCCC) has found that head and neck cancer patients receiving radiation as part of their treatment were less likely to suffer unwanted side effects such as worsening of diet, need for a feeding tube, or narrowing of the throat passage if they complied with a set of prescribed swallowing exercises called a swallow preservation protocol (SPP) during therapy.

30 Aug 2013

University Of Virginia Gets $14.4M Grant To Fight Hypertrophic Cardiomyopathy

...

28 Aug 2013

HCV treatment with sofosbuvir and ribavirin results in sustained virologic response

Treatment of chronic hepatitis C virus genotype 1 infection with the interferon-free regimen of sofosbuvir and ribavirin resulted in a high sustained virologic response rate in a patient population with unfavorable treatment characteristics, according to a study in the August 28 issue of JAMA.

28 Aug 2013

Researchers discover additional cystic fibrosis-causing mutations

Of the over 1,900 errors already reported in the gene responsible for cystic fibrosis, it is unclear how many of them actually contribute to the inherited disease. Now a team of researchers reports significant headway in figuring out which mutations are benign and which are deleterious. In so doing, they have increased the number of known CF-causing mutations from 22 to 127, accounting for 95 percent of the variations found in patients with CF.

26 Aug 2013

Twice-daily KALYDECO improves lung function in people with cystic fibrosis

Vertex Pharmaceuticals (Australia) Pty Ltd., announces the presentation of data from KALYDECO (ivacaftor) studies at the 10th Australasian Cystic Fibrosis Conference in Auckland, New Zealand, August 17 – 20, 2013, which further demonstrate the benefits of the medicine in people with cystic fibrosis ages 6 and older who have at least one copy of the G551D mutation in the cystic fibrosis transmembrane conductance regulator gene.

21 Aug 2013

Research: 2 forms of iron to treat cystic fibrosis lung infection

The bacterium Pseudomonas aeruginosa needs iron to establish and maintain a biofilm in the lungs of cystic fibrosis patients, and therapies have been proposed to deprive the bacteria of this necessary element.

20 Aug 2013

Report demonstrates clinical use of novel biomarker to assess cancer progression, inflammation

A groundbreaking peer reviewed case report by Dr. Isaac Eliaz, M.D. of Amitabha Medical Clinic, demonstrates for the first time the clinical use of novel biomarker galectin-3 to assess cancer progression and inflammation.

19 Aug 2013

Study: Herniated discs result from avulsion of tissue, rather than rupture

Herniated discs in the lower (lumbar) spine most often result from avulsion (separation) of the tissue connection between the disc and spinal bone, rather than rupture of the disc itself, according to a study in Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

16 Aug 2013

New discovery to fight against antibiotic-resistant superbugs

The fight against antibiotic-resistant superbugs has taken a step forward thanks to a new discovery by scientists at The University of Nottingham.

14 Aug 2013

Study: 3 enzymes required for building sugar superstructure involved in muscular dystrophies

For many inherited diseases, such as cystic fibrosis or Huntington disease, the disease-causing genetic mutation damages or removes a protein that has an essential role in the body. This protein defect is the root cause of the disease symptoms.

9 Aug 2013

AmpliPhi releases data on phage therapy for treatment of lung infections in Cystic Fibrosis patients

AmpliPhi BioSciences Corp. (OTC: APHB) ("AmpliPhi"), the leader in the development of bacteriophage-based antibacterial therapies to treat drug resistant bacterial infections, yesterday presented data relating to the use of bacteriophages in the treatment of Pseudomonas aeruginosa (P. aeruginosa) at the 20th Biennial Evergreen International Phage Meeting held in Olympia, Washington, USA. P. aeruginosa is the major cause of lung infections in cystic fibrosis (CF) patients.

8 Aug 2013

Microbiologists identify staph-killing compound that may be effective for osteomyelitis

Osteomyelitis, a debilitating bone infection most frequently caused by Staphylococcus aureus ("staph") bacteria, is particularly challenging to treat.

2 Aug 2013

Fibrosis News and Research

Further Reading

Patients with COPD show improvements in lung function with olodaterol

Parasites could be potential key to treating autoimmune diseases

New study reveals damaging effects of road-side pollution in people with bronchiectasis

Head and neck cancer patients receiving radiation benefit from swallowing exercises

FIBRO-TARGETS project aims to identify mechanisms involved in MIF, define therapeutic approaches

UNC study to explore technology use in screening newborns for genetic conditions

Women are 25% less likely to die post TAVI than men, says doctor

DE-MRI before ablation can stage atrial fibrosis and help predict success treatment

Head, neck cancer patients receiving radiation complied with SPP likely to suffer side effects

University Of Virginia Gets $14.4M Grant To Fight Hypertrophic Cardiomyopathy

HCV treatment with sofosbuvir and ribavirin results in sustained virologic response

Researchers discover additional cystic fibrosis-causing mutations

Twice-daily KALYDECO improves lung function in people with cystic fibrosis

Research: 2 forms of iron to treat cystic fibrosis lung infection

Report demonstrates clinical use of novel biomarker to assess cancer progression, inflammation

Study: Herniated discs result from avulsion of tissue, rather than rupture

New discovery to fight against antibiotic-resistant superbugs

Study: 3 enzymes required for building sugar superstructure involved in muscular dystrophies

AmpliPhi releases data on phage therapy for treatment of lung infections in Cystic Fibrosis patients

Microbiologists identify staph-killing compound that may be effective for osteomyelitis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News