Genomic News and Research

RSS

Research shines light on the effects of genomic variation on gut microbiome function

New research from Cornell scientists is exploring how human genetics impacts functions of the gut microbiome, and is expanding awareness of the role human genetics plays in shaping the microbiome.

18 Apr 2022

Mutation-acquiring potential of coronaviruses and efficacies of current COVID-19 vaccines against parent and mutant strains of SARS-CoV-2

Researchers reviewed the antibody resistance exhibited by SARS-CoV-2 variants.

18 Apr 2022

RNA interference triggers that target SARS-CoV-2 genome

Researchers screened ribonucleic acid interference against SARS-CoV-2.

18 Apr 2022

Genomic characterization of the circulating SARS-CoV-2 lineages in Papua New Guinea

A recent study characterized the SARS-CoV-2 lineages circulating in Papua New Guinea during the second wave of COVID-19.

15 Apr 2022

A comprehensive rule book for the design of safe and efficient therapeutic cells

Therapies based on engineered immune cells have recently emerged as a promising approach in the treatment of cancer.

15 Apr 2022

Yale research demonstrates the cancer relevance of known human genes

Following an analysis of over 12,000 human genes, research from Yale Cancer Center indicates there is cancer-relevant importance in a much larger proportion of human genes than current cancer research models suggest.

14 Apr 2022

Study explores role of APOBEC-mediated RNA editing in SARS-CoV-2 fitness

A new study investigated whether APOBEC proteins can directly edit the RNA sequence of SARS-CoV-2 to generate C-to-U mutations.

14 Apr 2022

Regulation of alternative splicing goes haywire in cells of a newly formed embryo

Alternative splicing is a fundamental biological process that allows cells to make many different types of mRNAs and proteins from a limited number of genes. For many animals, including humans, it is a feature that is essential for the development of complex cells such as muscles or neurons.

13 Apr 2022

The transmission dynamics of key SARS-CoV-2 mutations revealed by subtyping in new study

In a new study, researchers devised a method for reducing the size of a large collection of SARS-CoV-2 genomes by combining correlated single nucleotide variation sets with allelic association.

13 Apr 2022

Dysregulated retroelements associated with autoimmunity in COVID-19

Researchers investigate potential interactions between retro-elements shared between the human and coronavirus genomes.

12 Apr 2022

Epidemiologic characteristics of SARS-CoV-2 Omicron and Delta variant infection cases in Cantabria, Spain

Researchers performed a comparative assessment of the key epidemiological characteristics such as secondary attack rates, transmission, serial interval, and incubation period of SARS-CoV-2 infections by the Omicron and Delta variants.

12 Apr 2022

Novel Hendra virus variant detected in flying fox urine

Researchers reported on the detection of a novel Hendra virus variant of genotype 2 (HeV-g2) in the urine of grey-headed and black flying foxes in Australia.

12 Apr 2022

Drugs targeting DNA damage response pathway show therapeutic potential against advanced solid tumors

Results from early-stage clinical trials show two drugs that target the DNA damage response (DDR) pathway in cancers - ATR inhibitor elimusertib and PARP inhibitor AZD5305 - are safe and clinically beneficial in treating patients with advanced solid tumors.

11 Apr 2022

SARS-CoV-2 Omicron BA.2 sublineage outbreak aggravated by low population immunity in Hong Kong

A new study illustrated that inadequate population immunity exacerbated the SARS-CoV-2 Omicron BA.2 sublineage outbreak in Hong Kong.

11 Apr 2022

Study finds better immunotherapy response in lung cancer patients with genetic variant linked to autoimmune disease

A variant of the CTLA-4 gene associated with autoimmune disease was found to be more frequent in non-small cell lung cancer (NSCLC) patients who experienced an exceptionally high response to anti-PD-1 immunotherapy and higher immune-related side effects than in a comparable cohort of lung cancer patients and healthy individuals, according to data presented during the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

Genomic News and Research

Research shines light on the effects of genomic variation on gut microbiome function

Mutation-acquiring potential of coronaviruses and efficacies of current COVID-19 vaccines against parent and mutant strains of SARS-CoV-2

RNA interference triggers that target SARS-CoV-2 genome

Genomic characterization of the circulating SARS-CoV-2 lineages in Papua New Guinea

A comprehensive rule book for the design of safe and efficient therapeutic cells

Yale research demonstrates the cancer relevance of known human genes

Study explores role of APOBEC-mediated RNA editing in SARS-CoV-2 fitness

Regulation of alternative splicing goes haywire in cells of a newly formed embryo

The transmission dynamics of key SARS-CoV-2 mutations revealed by subtyping in new study

Dysregulated retroelements associated with autoimmunity in COVID-19

Epidemiologic characteristics of SARS-CoV-2 Omicron and Delta variant infection cases in Cantabria, Spain

Novel Hendra virus variant detected in flying fox urine

Drugs targeting DNA damage response pathway show therapeutic potential against advanced solid tumors

SARS-CoV-2 Omicron BA.2 sublineage outbreak aggravated by low population immunity in Hong Kong

Study finds better immunotherapy response in lung cancer patients with genetic variant linked to autoimmune disease

SARS-CoV-2 Delta-Omicron recombinant identified in a transplant patient treated with Sotrovimab

Study characterizes SARS-CoV-2 spike-specific cluster of differentiation 4+ T-cell response

Large-scale study sheds more light on the genetic basis of schizophrenia

SARS-CoV-2 detected using smartphone biosensor

Unique immune cell fingerprint can help rapidly identify better treatment for autoimmune disease

Industry focus eBook: Genomics (4th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News