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What does the future look like for TB care?

In this interview, we speak to Charles Wells from Gates MRI about their current research into tuberculosis (TB) as well as the recent updated guidelines for TB care.

5 Aug 2022

Heart failure arises from mutations in distinct genes, study finds

Heart failure is a common and devastating disorder for which there is no cure. Many cardiomyopathies - conditions that make it difficult for the heart to pump blood such as dilated cardiomyopathy (DCM) and arrhythmogenic cardiomyopathy (ACM) - can lead to heart failure, but treatments for patients with heart failure do not take these distinct conditions into account.

5 Aug 2022

Individual genetic defects lead to heart failure in different ways, consortium reports

Cardiomyopathy is not a uniform disease. Rather, individual genetic defects lead to heart failure in different ways, an international consortium reports in Science.

4 Aug 2022

Researchers discover two signaling pathways that are downregulated in human hearts after birth

Published today in Stem Cell Reports, researchers from the University of Minnesota Medical School discovered two signaling pathways that are downregulated in human hearts after birth.

4 Aug 2022

UAB researchers report a potential treatment for ARID1A-deficient bladder cancer

Metastatic bladder cancer is generally incurable, so new therapies are an urgent need. Researchers at the University of Alabama at Birmingham now report a potential treatment for a quarter of bladder cancers.

4 Aug 2022

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

Mitochondria are organelles found within most cells, best known for generating the chemical energy required to power cellular functions.

4 Aug 2022

Scientists develop a novel, highly-efficient sample preparation method for single-cell proteomics

The proteins that make up our cells hold within an entire world of information, which, when unlocked, can give us insights into the origins of many essential biological phenomena.

4 Aug 2022

Mice study reveals hepatic consequences of exposure to endocrine disrupting chemical mixtures

We are increasingly being exposed to endocrine-disrupting chemicals (EDCs) that interfere with the normal functioning of our hormones. Bisphenol A (BPA) and phthalates, which are widely used in consumer products including plastics, aluminum cans, pharmaceuticals, and cosmetics, are well-known EDCs.

4 Aug 2022

Study suggests an approach for promoting more equitable interpersonal treatment

Coaching patients to voice their concerns about their medical care and advocate for themselves can offset physicians' racial bias so it doesn't lead to inferior experiences for Black patients, a University of Michigan-led analysis found.

3 Aug 2022

BRAIN Center Phase 2 at the University of Houston receives funds from NSF

On any given day inside the BRAIN Center at the University of Houston, you might encounter visual artists, dancers and musicians, or even paralyzed individuals – all wearing brain caps to teach researchers about what they are thinking, creating or feeling while they move expressively, or try to regain movement.

3 Aug 2022

Study pinpoints a three-pronged approach that makes liver cancer cells stop growing

Liver cancer's rapid growth leads to a vulnerability in its energy-production and cell-building processes that may be potently exploited with a new combination-treatment strategy, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

3 Aug 2022

Substantial increases in cardiovascular trends contribute to a rising burden on the US health care system

By the year 2060, projected rates of cardiovascular risk factors and disease will increase significantly in the United States, according to a study published today in the Journal of the American College of Cardiology. Substantial increases in cardiovascular trends may contribute to a rising burden on the U.S. health care system and highlight the need for equitable access to prevention education and treatments now to prevent future disease.

3 Aug 2022

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

A fruit fly genome is not a just made up of fruit fly DNA – at least for one fruit fly species. New research from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) shows that one fruit fly species contains whole genomes of a kind of bacteria, making this finding the largest bacteria-to-animal transfer of genetic material ever discovered. The new research also sheds light on how this happens.

3 Aug 2022

Researchers aim to evaluate outcomes of visceral artery pseudoaneurysm in necrotizing pancreatitis

Published by the GIE Journal, University of Minnesota Medical School researchers aimed to evaluate the incidence, clinical presentation, management, and outcomes of visceral artery pseudoaneurysm (PSA) in necrotizing pancreatitis (NP).

2 Aug 2022

New research unravels why breastmilk-fed preemies are healthier than formula-fed infants

Human breastmilk has long been considered "liquid gold" among clinicians treating premature infants in a newborn intensive care unit.

2 Aug 2022

Pediatric adjuvant formulation offers protection against RSV in newborns

Respiratory syncytial virus (RSV) is the leading global cause of death in children under age 5 and lacks an effective vaccine. In a study from the Precision Vaccines Program at Boston Children's Hospital, a new vaccine formulation protected newborn mice against infection and evoked strong responses in immune cells from human newborns in the laboratory. Results were reported August 2 in Nature Communications.

2 Aug 2022

Carbon monoxide foam in the fight against inflammation

News-Medical speaks to Leo Otterbein about a novel way to deliver carbon monoxide to the body while bypassing its potentially hazardous effects.

2 Aug 2022

Brain & Behavior Research Foundation recognizes exceptional research in mental illness

The Brain & Behavior Research Foundation today announced the winners of its 2022 Klerman and Freedman Prizes, recognizing exceptional clinical and basic research in mental illness.

1 Aug 2022

Researchers find mechanisms behind the development of congenital birth defect

About one percent of the world population is born with a congenital heart defect, which affects about 40,000 U.S. births each year, but how these particular birth defects come about is largely unknown.

1 Aug 2022

The Alzheimer’s Association recognizes seven researchers for contributions to the field of dementia science

The Alzheimer’s Association will present seven awards at the Alzheimer’s Association International Conference 2022, recognizing researchers for their varied expertise, noteworthy achievements and innovative contributions to the field of Alzheimer’s and dementia science.

1 Aug 2022

Medical School News and Research

What does the future look like for TB care?

Heart failure arises from mutations in distinct genes, study finds

Individual genetic defects lead to heart failure in different ways, consortium reports

Researchers discover two signaling pathways that are downregulated in human hearts after birth

UAB researchers report a potential treatment for ARID1A-deficient bladder cancer

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

Scientists develop a novel, highly-efficient sample preparation method for single-cell proteomics

Mice study reveals hepatic consequences of exposure to endocrine disrupting chemical mixtures

Study suggests an approach for promoting more equitable interpersonal treatment

BRAIN Center Phase 2 at the University of Houston receives funds from NSF

Study pinpoints a three-pronged approach that makes liver cancer cells stop growing

Substantial increases in cardiovascular trends contribute to a rising burden on the US health care system

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

Researchers aim to evaluate outcomes of visceral artery pseudoaneurysm in necrotizing pancreatitis

New research unravels why breastmilk-fed preemies are healthier than formula-fed infants

Pediatric adjuvant formulation offers protection against RSV in newborns

Carbon monoxide foam in the fight against inflammation

Brain & Behavior Research Foundation recognizes exceptional research in mental illness

Researchers find mechanisms behind the development of congenital birth defect

The Alzheimer’s Association recognizes seven researchers for contributions to the field of dementia science

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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