Neurodegenerative Diseases News and Research

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Researchers identify important steps to understand mechanisms underlying pathogenic effect of prions

"When they are healthy, they look like tiny spheres; when they are malignant, they appear as cubes" stated Giuseppe Legname, principal investigator of the Prion Biology Laboratory at the Scuola Internazionale Superiore di Studi Avanzati (SISSA) in Trieste, when describing prion proteins.

25 Jan 2014

Scientists figure out key step in how free calcium is controlled in the body

Scientists at Johns Hopkins report they have figured out a key step in how "free" calcium - the kind not contained in bones - is managed in the body, a finding that could aid in the development of new treatments for a variety of neurological disorders that include Parkinson's disease.

24 Jan 2014

Scientists identify molecules that block accumulation of toxic eye protein responsible for early onset of glaucoma

Using a novel high-throughput screening process, scientists have for the first time identified molecules with the potential to block the accumulation of a toxic eye protein that can lead to early onset of glaucoma.

24 Jan 2014

Johns Hopkins researchers reveal how calcium is controlled in the body

Scientists at Johns Hopkins report they have figured out a key step in how “free” calcium — the kind not contained in bones — is managed in the body, a finding that could aid in the development of new treatments for a variety of neurological disorders that include Parkinson’s disease.

24 Jan 2014

Collaboration between NFL and GE seeks to improve safety of athletes, soldiers who sustain mild TBI

When the Broncos and the Seahawks meet on the gridiron for Superbowl XLVIII, player and team statistics - passer ratings, rushing yards, sacks and fumbles - will be tossed around like, well, a football.

24 Jan 2014

UT Southwestern' faculty receives Stanley J. Korsmeyer Award for contributions to understanding of autophagy

Dr. Beth Levine, a Howard Hughes Medical Institute Investigator and Director of the Center for Autophagy Research at UT Southwestern Medical Center, has received the 2014 Stanley J. Korsmeyer Award from the American Society for Clinical Investigation.

22 Jan 2014

Parkin and PINK1 function in vesicular trafficking pathway regulates mitochon-drial quality control

Scientists from the Montreal Neurological Institute and Hospital in Canada have discovered that two genes linked to hereditary Parkinson's disease are involved in the early-stage quality control of mitochondria.

22 Jan 2014

Research findings may offer new therapeutic target for management of Gaucher diseas

What causes brain damage and inflammation in severe cases of Gaucher disease? Little is known about the events that lead to brain pathology in some forms of the disease, and there is currently no treatment available - a bleak outlook for sufferers and their families. Now, scientists at the Weizmann Institute of Science have discovered a new cellular pathway implicated in Gaucher disease.

19 Jan 2014

Research uncovers new mechanism in brain cells that may help keep deadly neurological diseases in check

New research from David Westaway, PhD, of the University of Alberta and Jiri Safar, MD, Case Western Reserve University School of Medicine has uncovered a quality control mechanism in brain cells that may help keep deadly neurological diseases in check for months or years.

17 Jan 2014

New dye more effective in detecting, measuring cardiolipin in cell membranes

A team that includes Dartmouth College researchers has discovered a new way to detect cardiolipin, a key indicator of heart diseases and some genetic disorders.

16 Jan 2014

Research findings may offer new way to treat prion diseases

New research from David Westaway, PhD, of the University of Alberta and Jiri Safar, PhD, Case Western Reserve University School of Medicine has uncovered a quality control mechanism in brain cells that may help keep deadly neurological diseases in check for months or years.

16 Jan 2014

Study shows ability to make living human cells from biobanked brain tissue of Alzheimer's patients

Scientists at The New York Stem Cell Foundation (NYSCF) Research Institute, working in collaboration with scientists from Columbia University Medical Center (CUMC), for the first time generated induced pluripotent stem (iPS) cells lines from non-cryoprotected brain tissue of patients with Alzheimer's disease.

7 Jan 2014

Hotspots of fuel consumption in adult brain also show key characteristics of developing brain

Although brain growth slows as individuals age, some regions of the brain continue to develop for longer than others, creating new connections and remodeling existing circuitry.

7 Jan 2014

Researcher reveals how temperature impacts development of embryos

In nature, animals face a broad range of temperatures, and at times the heat can become taxing. When it becomes too hot to survive, some animals can simply migrate to more favorable climates, but what if you are a mere embryo confined within an egg and cannot escape the heat?

6 Jan 2014

MitoQ antioxidant reverses MS-like disease in animal

Researchers at Oregon Health & Science University have discovered that an antioxidant designed more than a dozen years ago to fight damage within human cells significantly helps symptoms in mice that have a multiple sclerosis-like disease.

27 Dec 2013

Studies yield new insights into molecular mechanisms that underlie learning process

Learning requires constant reconfiguration of the connections between nerve cells. Two new studies now yield new insights into the molecular mechanisms that underlie the learning process.

22 Dec 2013

Professor wins $1M to create medical devices that lead to greater control of prosthetics in soldiers

Dr. Walter Voit, assistant professor of materials science and engineering and mechanical engineering at The University of Texas at Dallas, has been awarded $1 million to create medical devices that will lead to greater control of prosthetics in wounded soldiers.

17 Dec 2013

Study reveals pathogenic factor that triggers prion and neurodegenerative diseases

Transmissible spongiform encephalopathy or prion disease is triggered by the conversion from cellular prion protein to pathogenic prion protein.

12 Dec 2013

EPSRC donates £5 million for dementia research

Health ministers from the G8 nations will meet in London today (11 December) to discuss the global health challenge posed by dementia. The summit aims to develop co-ordinated global action on dementia. One area of focus at the summit is preventing and delaying dementia.

11 Dec 2013

Biosimulation and epilepsy treatments: an interview with Dr. Serge Bischoff, CEO of Rhenovia and RHENEPI program director

The need for biosimulation is primarily to do with the very high attrition rate in drug development and especially in the development of drugs for the central nervous system.

10 Dec 2013

Neurodegenerative Diseases News and Research

Researchers identify important steps to understand mechanisms underlying pathogenic effect of prions

Scientists figure out key step in how free calcium is controlled in the body

Scientists identify molecules that block accumulation of toxic eye protein responsible for early onset of glaucoma

Johns Hopkins researchers reveal how calcium is controlled in the body

Collaboration between NFL and GE seeks to improve safety of athletes, soldiers who sustain mild TBI

UT Southwestern' faculty receives Stanley J. Korsmeyer Award for contributions to understanding of autophagy

Parkin and PINK1 function in vesicular trafficking pathway regulates mitochon-drial quality control

Research findings may offer new therapeutic target for management of Gaucher diseas

Research uncovers new mechanism in brain cells that may help keep deadly neurological diseases in check

New dye more effective in detecting, measuring cardiolipin in cell membranes

Research findings may offer new way to treat prion diseases

Study shows ability to make living human cells from biobanked brain tissue of Alzheimer's patients

Hotspots of fuel consumption in adult brain also show key characteristics of developing brain

Researcher reveals how temperature impacts development of embryos

MitoQ antioxidant reverses MS-like disease in animal

Studies yield new insights into molecular mechanisms that underlie learning process

Professor wins $1M to create medical devices that lead to greater control of prosthetics in soldiers

Study reveals pathogenic factor that triggers prion and neurodegenerative diseases

EPSRC donates £5 million for dementia research

Biosimulation and epilepsy treatments: an interview with Dr. Serge Bischoff, CEO of Rhenovia and RHENEPI program director

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