immunity News and Research

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Does leptin play a role in Parkinson’s disease?

Scientists review in vitro and in vivo evidence associated with Parkinson's disease and leptin.

26 Sep 2022

In vitro gut models reveal how microplastics affect the GI tract

Researchers hypothesize that exposure to polyethylene microplastics affect the human adult GI system in vitro under realistic conditions.

26 Sep 2022

UTHSC professor receives $5 million to explore the gut as therapeutic target for treating disease

Radhakrishna Rao, PhD, vice-chair and professor in the Department of Physiology at the University of Tennessee Health Science Center (UTHSC), has received two large national awards totaling $5 million for separate studies involving the gut as a therapeutic target for treating disease.

26 Sep 2022

Study demonstrates how pan-sarbecovirus ORF7a protein plays a role in evading host immunity

In a new study, researchers demonstrated how sarbecovirus family down-regulates major histocompatibility complex-I (MHC-I) surface expression to evade cellular immunity.

26 Sep 2022

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

In a new study, researchers followed up with individuals vaccinated with a COVID-19 vaccine based on the mRNA platform up to six months following Omicron BA.1 breakthrough infection to trace the evolution of their antibody immunity.

26 Sep 2022

Long-term follow-up of young people with COVID-19 vaccine myocarditis

In a recent study, researchers surveyed a comprehensive range of outcomes in patients diagnosed with myocarditis after COVID-19 vaccination in the United States.

26 Sep 2022

How effective are live-attenuated SARS-CoV-2 vaccines?

Researchers opined on the use of live-attenuated whole virus vaccines as COVID-19 vaccines.

26 Sep 2022

Common germline variants of APOE contribute to differential COVID-19 outcomes

Researchers investigated the relationship between APOE4 genotype and COVID-19 outcomes using genetic models of mice.

26 Sep 2022

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

Researchers presented the direct plasmid transfection method for SARS-CoV-2 virus-like particle production in insect cells and applied the VLPs to evaluate the efficacy of monoclonal antibodies and vaccinated donor sera.

26 Sep 2022

The impact of sleep fragmentation on the clonal diversity of immune cells and the genetic aging of the hematopoietic system

A new study shows that sleep does much more, regulating the normal production of blood cells. This finding underlines how essential a healthy sleep routine is for a normal life.

26 Sep 2022

Study of 9 million Swedes shows rapidly declining effectiveness of COVID vaccines against Omicron

The findings of a new Swedish study posted to the Preprints with The Lancet* server found that two COVID-19 vaccine doses provided effective long-term protection against infection before Omicron, but less protection against Omicron infection (dropping to 43% by week four and no protection by week 14).

25 Sep 2022

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

In a recent study posted to the medRxiv* preprint server, researchers in the United States described the safety, efficacy, and immunogenicity of the NVX-CoV2373 vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), tested in PREVENT-19 — a phase 3, randomized, placebo-controlled, observer-blinded trial among 12- to 17-year-old adolescents in the United States (U.S).

25 Sep 2022

A good night's sleep promotes immunity

In a recent study published in the Journal of Experimental Medicine, researchers in the United States used mice models to understand how sleep fragmentation affects immunological responses and the epigenetic modifications of hematopoietic stem and progenitor cells (HSPCs). They also conducted a sleep restriction trial in humans to determine HPSC programming and hematopoiesis.

25 Sep 2022

Study compares monkeypox PCR testing protocols and efficiency at two U.S. reference labs

In a recent study posted to the medRxiv* preprint server, researchers examined sample collection practices, epidemiological characteristics, and cycle threshold (Ct) values for polymerase chain reaction (PCR) tests used in two reference laboratories in the United States (U.S.) to detect monkeypox virus (MPXV).

25 Sep 2022

Generating a mutation in key molecules could offer new way to prevent and treat gonorrhea

Creating a mutation that inhibits how the bacterial pathogen Neisseria gonorrhoeae causes gonorrhea, a common sexually transmitted infection, could offer a new way to prevent and treat the disease, according to researchers in the Institute for Biomedical Sciences at Georgia State University.

23 Sep 2022

Study describes the dynamics of immune responses to triple COVID-19 vaccination

The effectiveness of the three-dose COVID-19 vaccination against SARS-CoV-2 and its variants has been described in detail in a recent study.

23 Sep 2022

Study paves the way for new therapies, vaccines that lead to stronger immunity against Covid-19

Why do some people become seriously ill with Covid-19, while others have no symptoms at all? The answer may lie in the proteins our immune system has previously been exposed to.

23 Sep 2022

Vaccine boosters and breakthrough infections provide substantial immunity against COVID-19

Vaccine boosters and breakthrough infections following vaccination both provide a substantial and potentially pandemic-breaking immunity against COVID-19, according to new laboratory research from Oregon Health & Science University.

22 Sep 2022

Dietary sugar may disrupt gut microbiota and induce metabolic complications

A new study demonstrates that dietary sugar increases the risk of metabolic syndrome by disrupting gut microbiota and suppressing protective T helper 17 (Th17) cells.

22 Sep 2022

What role does cross-reactive immunity play in the spread of a novel SARS-CoV-2 variant?

In a new study, researchers used mathematical modeling to examine the effect of cross-reactive immunity from previous infections on an emerging SARS-CoV-2 variant, and explored the probability of the novel variant causing widespread infection or fading out.

22 Sep 2022

immunity News and Research

Does leptin play a role in Parkinson’s disease?

In vitro gut models reveal how microplastics affect the GI tract

UTHSC professor receives $5 million to explore the gut as therapeutic target for treating disease

Study demonstrates how pan-sarbecovirus ORF7a protein plays a role in evading host immunity

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

Long-term follow-up of young people with COVID-19 vaccine myocarditis

How effective are live-attenuated SARS-CoV-2 vaccines?

Common germline variants of APOE contribute to differential COVID-19 outcomes

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

The impact of sleep fragmentation on the clonal diversity of immune cells and the genetic aging of the hematopoietic system

Study of 9 million Swedes shows rapidly declining effectiveness of COVID vaccines against Omicron

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

A good night's sleep promotes immunity

Study compares monkeypox PCR testing protocols and efficiency at two U.S. reference labs

Generating a mutation in key molecules could offer new way to prevent and treat gonorrhea

Study describes the dynamics of immune responses to triple COVID-19 vaccination

Study paves the way for new therapies, vaccines that lead to stronger immunity against Covid-19

Vaccine boosters and breakthrough infections provide substantial immunity against COVID-19

Dietary sugar may disrupt gut microbiota and induce metabolic complications

What role does cross-reactive immunity play in the spread of a novel SARS-CoV-2 variant?

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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