Therapy News and Research

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Low-amplitude electric fields help hard-to-heal chronic wounds

Naturally occurring electricity in our cells is key to how our bodies function, and that includes the healing of wounds.

5 Mar 2014

Researchers identify genes that appear to predict tumors that can evade detection by immune system

Johns Hopkins researchers say they have identified a set of genes that appear to predict which tumors can evade detection by the body’s immune system, a step that may enable them to eventually target only the patients most likely to respond best to a new class of treatment.

5 Mar 2014

Local hyperthermia treatment induces mechanism of anti-tumor immune resistance

A combination of iron-oxide nanoparticles and an alternating magnetic field, which together generate heat, have activated an immune system response to tumors in mice according to an accepted manuscript by Dartmouth-Hitchcock Norris Cotton Center researchers in the journal Nanomedicine: Nanotechnology, Biology and Medicine released online on February 24, 2014.

5 Mar 2014

New probes help to quantify normally folded and misfolded conformations of protein in cells

Scientists at The Scripps Research Institute (TSRI) have invented small-molecule folding probes that enable them to quantify functional, normally folded and disease-associated misfolded conformations (shapes) of a protein-of-interest in cells under different conditions.

5 Mar 2014

Researchers find antibody that may be used in future treatments for recurrent small-cell lung cancer

Researchers at Norris Cotton Cancer Center have found an antibody that may be used in future treatments for recurrent small-cell lung cancer, which currently has no effective therapy.

5 Mar 2014

Mcl-1 protein enables NSCLC to survive radiation and drug treatments

Researchers at the Translational Genomics Research Institute have discovered a protein, Mcl-1, that helps enable one of the most common and deadly types of cancer to survive radiation and drug treatments.

5 Mar 2014

Study: Combination intervention completely eliminates HIV transmission

A computer model has created the most effective formula for reducing the spread of HIV among drug users in New York City over the next 25 years.

5 Mar 2014

Experimental drug nivolumab shrinks tumors in patients with advanced melanoma

An experimental drug aimed at restoring the immune system's ability to spot and attack cancer halted cancer progression or shrank tumors in patients with advanced melanoma, according to a multisite, early-phase clinical trial at Johns Hopkins Kimmel Cancer Center and 11 other institutions. All patients had experienced disease progression despite prior systemic therapies, and most had received two or more prior treatments.

4 Mar 2014

GTx provides clinical updates, reports financial results for fourth quarter and full year 2013

GTx, Inc. today provided a Company update and reported financial results for the fourth quarter and full year 2013.

4 Mar 2014

Advanced Accelerator Applications agrees to acquire 100% shares of Imaging Equipment

Advanced Accelerator Applications, a fast growing international specialist in Molecular Nuclear Medicine (MNM), announced today that it has entered into an agreement to acquire 100% of the shares of Imaging Equipment Ltd, a privately-held UK distributor of nuclear medicine products and technologies, in newly issued AAA shares.

4 Mar 2014

UNM physician performs TORS procedure on patient with stage IV throat cancer

When Charlie Guinn sits down to eat with his lovely wife of 39 years, he thoroughly enjoys each bite. It's not just the food; the entire experience is a celebration. Just over a year ago, Mr. Guinn learned that he had stage IV throat cancer.

4 Mar 2014

Neuropsychologists develop new technique to restore patients' perception of sounds and images

Stroke is one of the most common neurological disorders worldwide. Many stroke survivors are left with serious health problems. Some patients, for example, find themselves unable to perceive one side of their body and can have problems seeing, hearing and feeling on that side.

4 Mar 2014

AJT describes novel approach to long-term tolerance in organ transplantation

REGiMMUNE Corporation announced that the American Journal of Transplantation (AJT) has published its paper that describes a novel approach to long-term tolerance in organ transplantation with continuous administration of immune suppressants.

4 Mar 2014

Drug that unleashes immune system can produce lasting remissions in patients with melanoma

A drug that unleashes the immune system to attack cancer can produce lasting remissions and hold the disease in check - for more than two years, in some cases - in many patients with advanced melanoma, according to a new study by researchers at Dana-Farber Cancer Institute, Johns Hopkins University, Yale University, and allied institutions.

4 Mar 2014

Medical student receives award for finding out drugs to treat peripheral vascular disease

Working at a Saint Louis University laboratory, second-year medical student Weston Gordon performed several studies investigating two novel drug therapies that may be useful in the treatment of peripheral vascular disease in patients with Type 2 diabetes.

4 Mar 2014

Medtronic, Aetna team up to help insured members with uncontrolled type 2 diabetes

Beginning this month, Aetna and Medtronic, Inc. will work with doctors in a new program to reach up to 300 fully insured members with uncontrolled type 2 diabetes who may improve their health using insulin pump therapy.

From Medtronic 4 Mar 2014

Doctors devise new way to treat atrial fibrillation

Doctors in the U.S. and Japan have devised a way to treat atrial fibrillation by adding a little alcohol to minimally invasive therapies that target a cluster of misbehaving nerves known to trigger arrhythmia. In the most recent Journal of the American College of Cardiology (online before print), the researchers say the new therapy may dull or stop the transmission of electrical impulses that cause atrial fibrillation.

4 Mar 2014

AbbVie's PEARL-III study meets primary, secondary endpoints in patients with chronic GT1b HCV infection

The first detailed results from AbbVie's pivotal phase III study, PEARL-III, were presented today as part of the 21st Conference on Retroviruses and Opportunistic Infections (CROI) press conference and will also be presented as a late-breaker at the conference on March 4.

4 Mar 2014

Arrowhead receives approval to initiate Phase 2a clinical trial of ARC-520 for chronic HBV infection

Arrowhead Research Corporation (NASDAQ: ARWR), a biopharmaceutical company developing targeted RNAi therapeutics, today announced that it received regulatory approval to begin a Phase 2a clinical trial of ARC-520, its RNAi-based drug candidate for the treatment of chronic hepatitis B virus (HBV) infection.

4 Mar 2014

Naurex's GLYX-13 receives FDA Fast Track designation

Naurex Inc. today announced that the U.S. Food and Drug Administration has granted Fast Track designation to the investigation of GLYX-13, the company's rapid-acting antidepressant in Phase 2 clinical development, as adjunctive therapy in major depressive disorder.

4 Mar 2014

Therapy News and Research

Low-amplitude electric fields help hard-to-heal chronic wounds

Researchers identify genes that appear to predict tumors that can evade detection by immune system

Local hyperthermia treatment induces mechanism of anti-tumor immune resistance

New probes help to quantify normally folded and misfolded conformations of protein in cells

Researchers find antibody that may be used in future treatments for recurrent small-cell lung cancer

Mcl-1 protein enables NSCLC to survive radiation and drug treatments

Study: Combination intervention completely eliminates HIV transmission

Experimental drug nivolumab shrinks tumors in patients with advanced melanoma

GTx provides clinical updates, reports financial results for fourth quarter and full year 2013

Advanced Accelerator Applications agrees to acquire 100% shares of Imaging Equipment

UNM physician performs TORS procedure on patient with stage IV throat cancer

Neuropsychologists develop new technique to restore patients' perception of sounds and images

AJT describes novel approach to long-term tolerance in organ transplantation

Drug that unleashes immune system can produce lasting remissions in patients with melanoma

Medical student receives award for finding out drugs to treat peripheral vascular disease

Medtronic, Aetna team up to help insured members with uncontrolled type 2 diabetes

Doctors devise new way to treat atrial fibrillation

AbbVie's PEARL-III study meets primary, secondary endpoints in patients with chronic GT1b HCV infection

Arrowhead receives approval to initiate Phase 2a clinical trial of ARC-520 for chronic HBV infection

Naurex's GLYX-13 receives FDA Fast Track designation

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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