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UC San Diego researchers awarded two grants for investigating stem cell-based therapies

The governing board of the California Institute for Regenerative Medicine unanimously approved this week two grants worth more than $2.2 million to University of California San Diego School of Medicine researchers investigating stem cell-based therapies for a rare genetic disorder that affects the heart and a chronic, progressive affliction of the lungs.

20 Jul 2018

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

The U.S. Food and Drug Administration today approved Tibsovo (ivosidenib) tablets for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) who have a specific genetic mutation.

20 Jul 2018

Study looks into mechanisms that control sleep and wakefulness

Sleep is an autonomic process and is not always under our direct, voluntary control. Awake or asleep, we are basically under the regulation of two biological processes: sleep homeostasis, commonly known as 'sleep pressure', and the circadian rhythm, otherwise known as the 'body clock'.

20 Jul 2018

New research project investigates alternative treatments for eye infections

Fight for Sight has announced funding for an innovative research project that will investigate whether compounds used to treat snake venom and bee stings could provide an alternative to antibiotics in treating eye infection.

20 Jul 2018

Karius Test accurately detects invasive fungal infections, shows study

Karius, a life sciences company transforming infectious disease diagnostics with genomics and data through the innovative use of next-generation sequencing to analyze microbial cell-free DNA, announced today the positive results of a clinical study using blood samples from patients with confirmed invasive fungal infections.

20 Jul 2018

AVITA Medical expands management team to support launch of RECELL device to treat burns

AVITA Medical today announced that it expanded its management team in the commercial, legal and medical affairs functions to support the planned U.S. launch of the RECELL® Autologous Cell Harvesting Device in the treatment of burns

20 Jul 2018

Researchers uncover cause for progression of prostate cancer to incurable stage

Researchers at the University of Oulu in Finland have discovered novel genes and mechanisms that can explain how a genomic variant in a single nucleotide polymorphism rs11672691 influences prostate cancer aggressiveness.

20 Jul 2018

Researchers present evidence of phage cooperation when attacking CRISPR-containing bacteria

CRISPR, or clustered regularly interspaced short palindromic repeats, are an essential part of bacterial immunity designed to defend against foreign DNA. In bacteria, CRISPR acts just like it does in human cells as a pair of scissors, in their case with the goal of cutting strands of infecting DNA.

20 Jul 2018

Drug in clinical trials for Parkinson's disease offers hope for treating heart failure

A drug currently in clinical trials for treating symptoms of Parkinson's disease may someday have value for treating heart failure, according to results of early animal studies by Johns Hopkins Medicine researchers.

20 Jul 2018

AbbVie submits supplemental NDA to FDA for venetoclax to treat acute myeloid leukemia

AbbVie, a research-based global biopharmaceutical company, today announced it submitted a supplemental New Drug Application to the U.S. Food and Drug Administration for venetoclax in combination with a hypomethylating agent or in combination with low-dose cytarabine for the treatment of newly diagnosed patients with acute myeloid leukemia who are ineligible for intensive chemotherapy.

20 Jul 2018

Whole-brain LIPUS therapy improves cognitive dysfunction in mice simulating dementia, Alzheimer's

Ultrasound waves applied to the whole brain improve cognitive dysfunction in mice with conditions simulating vascular dementia and Alzheimer's disease.

20 Jul 2018

PureTech Health collaborates with Roche to advance oral administration of antisense oligonucleotides

PureTech Health plc, a clinical-stage biopharmaceutical company developing novel medicines focused on the Brain-Immune-Gut Axis, today announced that it has entered into a multiyear collaboration with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc., to advance PureTech's milk-derived exosome platform technology for the oral administration of Roche's antisense oligonucleotide platform.

20 Jul 2018

Dr Maddy Parsons receives Royal Microscopical Society Life Science Medal

Dr Maddy Parsons, a Group Leader in the Randall Division of Cell & Molecular Biophysics, has been awarded the Royal Microscopical Society Life Science Medal for her outstanding scientific contribution to applying microscopy in the field of cell biology.

20 Jul 2018

Genetic sequencing reveals new clues to aggressiveness of prostate cancer

Using genetic sequencing, scientists have revealed the complete DNA makeup of more than 100 aggressive prostate tumors, pinpointing important genetic errors these deadly tumors have in common.

20 Jul 2018

Researchers raise viability of cloned mice using somatic cell nuclear transfer method

An international group of researchers have raised the viability of mice that were cloned using a method called somatic cell nuclear transfer, by stimulating two epigenetic factors, and by doing this have shown that creating cloned animals more efficiently will require further work in the area of epigenetics.

20 Jul 2018

Using miniature drug-filled nanocarriers to target headaches and tumors

Scientists at the Mainz University Medical Center and the Max Planck Institute for Polymer Research have developed a new method to enable miniature drug-filled nanocarriers to dock on to immune cells, which in turn attack tumors.

20 Jul 2018

Novel tool predicts genes that cause disease due to production of truncated proteins

Predicting genes that can cause disease due to the production of truncated or altered proteins that take on a new or different function, rather than those that lose their function, is now possible thanks to an international team of researchers, including researchers from Baylor College of Medicine, that has developed a new analytical tool to effectively and efficiently predict such candidate genes.

20 Jul 2018

B Cell News and Research

UC San Diego researchers awarded two grants for investigating stem cell-based therapies

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

Study looks into mechanisms that control sleep and wakefulness

New research project investigates alternative treatments for eye infections

Karius Test accurately detects invasive fungal infections, shows study

AVITA Medical expands management team to support launch of RECELL device to treat burns

Researchers uncover cause for progression of prostate cancer to incurable stage

Researchers present evidence of phage cooperation when attacking CRISPR-containing bacteria

Drug in clinical trials for Parkinson's disease offers hope for treating heart failure

AbbVie submits supplemental NDA to FDA for venetoclax to treat acute myeloid leukemia

Whole-brain LIPUS therapy improves cognitive dysfunction in mice simulating dementia, Alzheimer's

PureTech Health collaborates with Roche to advance oral administration of antisense oligonucleotides

Dr Maddy Parsons receives Royal Microscopical Society Life Science Medal

Genetic sequencing reveals new clues to aggressiveness of prostate cancer

Researchers raise viability of cloned mice using somatic cell nuclear transfer method

Using miniature drug-filled nanocarriers to target headaches and tumors

Novel tool predicts genes that cause disease due to production of truncated proteins

Researchers identify enzyme as potential new drug target for blood disorders

Scientists move one step further in developing eye drops to treat age-related macular degeneration

ZHX2 protein could offer a new treatment strategy for kidney cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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