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Decreased bacterial diversity in gut linked with CRC risk

Decreased diversity in the microbial community found in the human gut is associated with colorectal cancer, according to a new study published December 6 in the Journal of the National Cancer Institute.

9 Dec 2013

PKM2 protein controls mitosis, saving cancer cells from death and promoting brain tumor growth

Researchers have caught a protein they previously implicated in a variety of cancer-promoting roles performing a vital function in cell division, survival and development of brain tumors.

8 Dec 2013

Covidien signs definitive agreement to acquire outstanding shares of Given Imaging

Covidien plc and Given Imaging Ltd. today announced a definitive agreement under which Covidien will acquire all of the outstanding shares of Given Imaging for $30.00 per share in cash, for a total of approximately $860 million, net of cash and investments acquired. This transaction provides Covidien additional scale and scope to serve the multibillion dollar global gastrointestinal market and supports the Company's strategy to comprehensively address key global specialties and procedures.

8 Dec 2013

Cancer survival rates still vary widely between European countries

Cancer survival still varies widely between European countries despite major improvements in cancer diagnosis and treatment during the first decade of the 21st century, according to the latest EUROCARE-5 reports covering over 50% of the adult and 77% of the childhood population of Europe.

6 Dec 2013

Biocartis, VIB partner to develop novel MSI biomarkers for colorectal cancer

Today Biocartis and VIB announced their exclusive license agreement on a novel panel of microsatellite instability biomarkers for several cancers, in particular colorectal cancer.

From Biocartis 6 Dec 2013

Cancer triggers scleroderma, shows evidence

Johns Hopkins scientists have found evidence that cancer triggers the autoimmune disease scleroderma, which causes thickening and hardening of the skin and widespread organ damage.

6 Dec 2013

C. difficile doesn’t harm infants, but serves as a reservoir to affect adults

Infants and toddlers frequently carry toxigenic Clostridium difficile, usually with no harm to themselves, but can serve as a reservoir and spread the bacteria to adults in whom it can cause severe disease, according to a study by a team of Swedish researchers published ahead of print in the Journal of Clinical Microbiology.

4 Dec 2013

SMART's G-EYE balloon technology to be integrated on PENTAX Medical's full HD+ colonoscopes

SMART Medical Systems Ltd., a developer and manufacturer of innovative endoscopy products, announced a strategic alliance with PENTAX Medical, an industry leader in endoscopic imaging. Under the alliance, SMART's novel G-EYE™ balloon technology will be integrated on PENTAX Medical's full HD+ colonoscopes, and will be distributed by PENTAX Medical in Europe, the Middle East and Africa.

4 Dec 2013

Direct radiographic imaging reveals negative impact of adiposity in older men and women

Researchers at the National Institute for Aging are working to improve understanding about obesity and cancer. A study, published today in the journal Applied Physiology, Nutrition, and Metabolism, is the first to use direct radiographic imaging of adipose tissue rather than estimates like body mass index (BMI) or waist circumference, and focuses on the relationship between obesity and cancer risk in aging populations. Findings emphasize the negative impact of adiposity on long term health particularly for older men and women.

4 Dec 2013

VolitionRx's two-assay test can detect 85% of colorectal cancer, more than 50% of precancerous polyps

VolitionRx Limited, a life sciences company focused on developing blood-based diagnostic tests for different types of cancer, today releases new data showing that when combining two of its proprietary NuQ assays into one test, they can achieve 85% detection rates at 85% specificity for colorectal cancer. The data also shows that Volition’s two-assay test can detect more than 50% of precancerous polyps. These new findings come from its ongoing prospective study with CHU Dinant Godinne | UCL Namur Hospital in Belgium.

4 Dec 2013

Better understanding of cancer evolution could help in early detection of cancers

A new appreciation of how cancer cells evolve could help scientists design better screening methods to catch cancer before it advances.

4 Dec 2013

Findings could have important implications for personalized treatment of colon cancer

A common observation in oncology is the phenomenon that a patient with a tumor receives a drug and responds very well, but after a few months the cancer comes back and is now resistant to previously administered chemotherapy. What happened? Many mechanisms contribute to explain this effect called "acquired resistance", but today the group Manel Esteller, Director of Epigenetics and Cancer Biology at the Bellvitge Biomedical Research Institute, ICREA researcher and Professor of Genetics at the University of Barcelona, describes in the official Journal of the National Cancer Research Center in the United States, The Journal of The National Cancer Institute, the existence of epigenetic differences that explain the lack of response of the tumor recurs.

4 Dec 2013

Older HIV-positive men at higher risk of HPV that causes anal cancer

Human papillomavirus, or HPV, which can cause cervical cancer in women, is also known to cause anal cancer in both women and men. Now, a study led by researchers at the UCLA School of Nursing has found that older HIV-positive men who have sex with men are at higher risk of becoming infected with the HPVs that most often cause anal cancer.

4 Dec 2013

A new approach for treating colorectal cancer

Scientists and surgeons at Princess Margaret Cancer Centre have discovered a promising new approach to treating colorectal cancer by disarming the gene that drives self-renewal in stem cells that are the root cause of disease, resistance to treatment and relapse.

4 Dec 2013

CTCs serve as clinical tool to determine patient’s response to chemotherapy

Scientists from Granada have demonstrated, for the first time, that detecting circulating tumour cells (CTCs) in blood and studying the presence of certain genetic markers in them is a technique that allows specialists to predict, with great precision, the response that advanced-cancer patients will have to chemotherapy, as well as the associated secondary effects they may suffer.

4 Dec 2013

Researchers find way to replace Paneth cells with two small molecules that maintain stem cells

Researchers at MIT and Brigham and Women's Hospital have shown that they can grow unlimited quantities of intestinal stem cells, then stimulate them to develop into nearly pure populations of different types of mature intestinal cells. Using these cells, scientists could develop and test new drugs to treat diseases such as ulcerative colitis.

3 Dec 2013

Research show that risk of diverticulosis is lower than previously thought

People who have diverticulosis, or pouches in the lining of the colon, often worry that they will eventually develop a painful and sometimes serious condition called diverticulitis, as previous research has shown that one in four, or up to 25 percent, of those with the condition will.

3 Dec 2013

Special issue of JACR focuses on the role of imaging-based screening in preventive medicine

To be published online Monday, Dec. 2, a special issue of the Journal of the American College of Radiology addresses imaging-based screening and radiology's increasing role in preventive medicine. Topics covered include breast density legislation, digital breast tomosynthesis (or 3-D mammography), lung cancer screening and computed tomography colonography reimbursement.

2 Dec 2013

Researchers discover promising new approach for colorectal cancer treatment

2 Dec 2013

Diagnosing colonic polyps: an interview with Dr. Haili Wang, Metabolomic Technologies Inc. (MTI)

Colorectal cancer is a leading cause of death in North America, but it is preventable if found at the colonic polyp stage. Currently, only 39% of colorectal cancer cases in the US are diagnosed at an early and treatable stage.

28 Nov 2013

Colon News and Research

Decreased bacterial diversity in gut linked with CRC risk

PKM2 protein controls mitosis, saving cancer cells from death and promoting brain tumor growth

Covidien signs definitive agreement to acquire outstanding shares of Given Imaging

Cancer survival rates still vary widely between European countries

Biocartis, VIB partner to develop novel MSI biomarkers for colorectal cancer

Cancer triggers scleroderma, shows evidence

C. difficile doesn’t harm infants, but serves as a reservoir to affect adults

SMART's G-EYE balloon technology to be integrated on PENTAX Medical's full HD+ colonoscopes

Direct radiographic imaging reveals negative impact of adiposity in older men and women

VolitionRx's two-assay test can detect 85% of colorectal cancer, more than 50% of precancerous polyps

Better understanding of cancer evolution could help in early detection of cancers

Findings could have important implications for personalized treatment of colon cancer

Older HIV-positive men at higher risk of HPV that causes anal cancer

A new approach for treating colorectal cancer

CTCs serve as clinical tool to determine patient’s response to chemotherapy

Researchers find way to replace Paneth cells with two small molecules that maintain stem cells

Research show that risk of diverticulosis is lower than previously thought

Special issue of JACR focuses on the role of imaging-based screening in preventive medicine

Researchers discover promising new approach for colorectal cancer treatment

Diagnosing colonic polyps: an interview with Dr. Haili Wang, Metabolomic Technologies Inc. (MTI)

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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