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SOCS1 silencing could help enhance vaccines against HIV

Researchers from Baylor College of Medicine have shown that switching off a molecule that helps regulate dendritic cells, specialized white blood cells that activate the immune system, could help the host fight HIV infection.

4 Jan 2006

Women suffering lupus OK to take oral contraceptives

Major study of women with either inactive or stable systemic lupus erythematosus (lupus) – a disease in which the body's immune system mistakenly attacks and damages healthy tissues of the skin, joints and internal organs – were able to take oral contraceptives without increased risk of flares, or periods of increased disease activity, that characterize the disease.

22 Dec 2005

AMN107 drug shows promise in leukemia resistance to Gleevec

The targeted agent AMN107 can produce dramatic benefits in patients with some forms of leukemia that are resistant to Gleevec, the standard therapy for these cancers, say researchers at The University of Texas M. D. Anderson Cancer Center.

13 Dec 2005

Common garden plant may hold cure for leukemia

Scientists in the U.S. believe they have identified a new pathway in the progression of chronic myelogenous leukemia (CML).

12 Dec 2005

Its true - marriage can be bad for your health!

U.S. researchers have yet more proof that an unhappy marriage is bad for your health.

6 Dec 2005

Analysis of Fcg Receptor haplotypes in rheumatoid arthritis

People with a specific combination of variants of two genes, encoding two different receptors for the antibody Fc gamma, are three times more likely to develop rheumatoid arthritis than individuals with different variant combinations.

28 Nov 2005

Compound from Salinispora (marine bacteria) kills blood cancer cells

An anti-cancer compound derived from bacteria dwelling in ocean-bottom sediments appears in laboratory tests to be a potent killer of drug-resistant multiple myeloma cells, and potentially with less toxicity than current treatments, report Dana-Farber Cancer Institute researchers in the November issue of Cancer Cell.

21 Nov 2005

Possible viral cause of Kawasaki disease identified

In an important discovery in infectious disease research, a team of scientists from Northwestern University has identified a possible viral cause of Kawasaki disease, the most common cause of acquired heart disease in children in developed nations.

20 Nov 2005

Plant extract forskolin may lead to leukemia treatment

Scientists here have identified a new pathway in the progression of chronic myelogenous leukemia (CML). They also discovered that an extract from the root of a common ornamental plant can suppress the process.

20 Nov 2005

Trichostatin A may fight lupus and atherosclerosis simultaneously

People with lupus are prone to premature accelerated atherosclerosis. Now scientists at Wake Forest University School of Medicine think they have a way to prevent or decrease this atherosclerosis and prevent heart attacks.

16 Nov 2005

FLT-1 blockers, cutting the legs of leukaemia

Leukaemia is characterised by an uncontrolled growth of abnormal blood cells in the bone marrow (BM).

14 Nov 2005

Scientists discover why lung, but not skin, anthrax infections are lethal

Scientists from the Max Planck Institute for Infection Biology in Berlin discovered why lung, but not skin, anthrax infections are lethal. As reported in the newest issue of PloS Pathogen (November 2005) Neutrophils, a form of white blood cells, play a key role in anthrax infections.

13 Nov 2005

Fc gamma receptor gene variants associated with rheumatoid arthritis

10 Nov 2005

Study proves the effectiveness of Vfend for the treatment of candidemia

Using Vfend (voriconazole) for the treatment of nonneutropenic patients with candidemia, an often-fatal hospital-acquired bloodstream infection, is as effective as a regimen of two older antifungals and carries fewer serious side effects than that regimen.

7 Nov 2005

Unique approach to enhance the immune system in patients with breast or colorectal cancer

The study uses a potent immune-enhancing gene delivered directly into the cancer cells to make them look foreign to the body's immune system, which will then attack and destroy the cancer.

1 Nov 2005

$107.6 million grant for malaria vaccine candidate

In an important step toward developing an effective malaria vaccine, the Bill & Melinda Gates Foundation has announced a $107.6 million grant to the PATH Malaria Vaccine Initiative (MVI) to extend the public-private partnership between MVI and GlaxoSmithKline Biologicals (GSK Bio) to develop GSK Bio's malaria vaccine for children in Africa.

30 Oct 2005

New approaches to counteract platelet shortages

Availability of safe platelets is a fundamental blood transfusion challenge and can be especially problematic in times of emergency. Several studies presented at the annual American Association of Blood Banks (AABB) meeting today demonstrate new approaches to counteract platelet shortages by enhancing the safety of whole blood derived platelets, precluding the need to rely on only those obtained through apheresis.

17 Oct 2005

Possible explanation for the higher incidence of lung cancer in African Americans

Faulty cell cycle "checkpoints" that fail to respond to DNA damage effectively may contribute to the high incidence of lung cancer in African-Americans, say researchers at Georgetown University's Lombardi Comprehensive Cancer Center and the National Cancer Institute (NCI).

16 Oct 2005

Why breast black cancer patients experience lower survival rates than other women

Black women with stage I or II breast cancer are more likely than their counterparts of other races to abandon chemotherapy before completing their full course of treatment, according to a recent Columbia University Medical Center study.

12 Oct 2005

New fungal defensin, plectasin, possesses as much power as penicillin

A peptide identified in a fungus found in northern European pine forests possesses as much power as penicillin as well as vancomycin, according to an international team of researchers.

12 Oct 2005