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Novel tool predicts genes that cause disease due to production of truncated proteins

Predicting genes that can cause disease due to the production of truncated or altered proteins that take on a new or different function, rather than those that lose their function, is now possible thanks to an international team of researchers, including researchers from Baylor College of Medicine, that has developed a new analytical tool to effectively and efficiently predict such candidate genes.

20 Jul 2018

Researchers identify enzyme as potential new drug target for blood disorders

Medical researchers have identified a key signaling protein that regulates hemoglobin production in red blood cells, offering a possible target for a future innovative drug to treat sickle cell disease.

20 Jul 2018

Scientists move one step further in developing eye drops to treat age-related macular degeneration

Scientists at the University of Birmingham are one step closer to developing an eye drop that could revolutionize treatment for age-related macular degeneration.

20 Jul 2018

ZHX2 protein could offer a new treatment strategy for kidney cancer

University of North Carolina Lineberger Comprehensive Cancer Center scientists have uncovered a potential therapeutic target for kidney cancers that have a common genetic change.

20 Jul 2018

New discovery could save millions of lives from fatal fungal infections

Life-threatening fungal infections affect more than two million people worldwide. Effective antifungal medications are very limited.

20 Jul 2018

Scientists demonstrate a new regulation mechanism for skeletal muscles

An international team of scientists from the University of Florence, Italy and the Randall Division in collaboration with the ESRF, the European Synchrotron, Grenoble, France, demonstrated a new regulation mechanism for skeletal muscle.

20 Jul 2018

Gestational diabetes may increase offspring's heart disease risk

Gestational diabetes may increase the risk of blood vessel dysfunction and heart disease in offspring by altering a smooth muscle protein responsible for blood vessel network formation.

19 Jul 2018

FAU researchers find possible cause of Parkinson’s disease in the patients’ immune system

Parkinson's disease, formerly also referred to as shaking palsy, is one of the most frequent disorders affecting movement and the nervous system.

19 Jul 2018

Protective qualities of 'good cholesterol' reduce after menopause

Levels of high density lipoprotein (HDL) may not accurately represent cardiovascular risk in older women, according to a new study.

19 Jul 2018

Kite collaborates with Gadeta to develop novel gamma delta TCR therapies for various cancers

Kite, a Gilead Company, and Gadeta B.V., a privately-held company focused on the discovery and development of novel cancer immunotherapies based on gamma delta T cell receptors, have entered into a strategic collaboration to develop novel gamma delta TCR therapies in various cancers.

19 Jul 2018

Biophysicists use infrared sensor as new method for drug discovery

Using an infrared sensor, biophysicists at Ruhr-Universität Bochum have succeeded in analyzing quickly and easily which active agents affect the structure of proteins and how long that effect lasts.

19 Jul 2018

WFN to highlight clean air for brain health on World Brain Day 2018

Global air pollution is not a problem that only affects lung health. Recent data show that airborne pollutants account for 30 percent of acute stroke cases worldwide.

19 Jul 2018

TGen opens tissue donation portal to advance DIPG research

A tissue donation portal opened today at the Translational Genomics Research Institute (TGen), which will advance research towards new treatments for an aggressive brain cancer that mostly strikes young children.

19 Jul 2018

Research project investigates snake venom treatment as antibiotic alternative for eye infections

An innovative University of Liverpool research project that will investigate whether compounds used to treat snake venom and bee stings could provide an alternative to antibiotics in treating eye infection has been awarded £170,000 by the charity Fight for Sight.

19 Jul 2018

Researchers unravel how ALL invades the central nervous system

A deadly feature of acute lymphoblastic leukemia is its invasion of the central nervous system.

19 Jul 2018

Study identifies RNA molecules that regulate male hormones in prostate cancer

In most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone.

19 Jul 2018

New proteomics studies help gain more insights into Alzheimer's, cancer and listeriosis

The brains of people with Alzheimer's disease contain many protein aggregates outside of cells, known as plaques. These are mainly made of the peptide amyloid-beta, which is released from the plasma membrane when the protease BACE1 cleaves its membrane-anchored precursor protein.

19 Jul 2018

Scientists study adverse effects of carbon, silicon nanotubes and carbon nanofibers

Nanoparticles with a wide range of applying, including medicine, damage cells of microalgae Heterosigma akashivo badly. This algae species is widely spread in the Russian Far East marine area. The acute toxic effect exhibited at concentrations of 100 mg/l of carbon nanotubes and silicon nanotubes in the sea- or fresh water.

19 Jul 2018

Researchers gain more insight into how FUS protein causes ALS and FTLD

The mutated and aggregated protein FUS is implicated in two neurodegenerative diseases: amyotrophic lateral sclerosis and frontotemporal lobar degeneration.

19 Jul 2018

Researchers identify subtypes of retinal ganglion cells using single-cell RNA sequencing

Single-cell sequencing technologies are filling in fine details in the catalog of life. Researchers at the University of Connecticut Health Center and The Jackson Laboratory have identified 40 subtypes of retinal ganglion cells along with the genetic markers and transcription factors that differentiate them.

19 Jul 2018

B Cell News and Research

Novel tool predicts genes that cause disease due to production of truncated proteins

Researchers identify enzyme as potential new drug target for blood disorders

Scientists move one step further in developing eye drops to treat age-related macular degeneration

ZHX2 protein could offer a new treatment strategy for kidney cancer

New discovery could save millions of lives from fatal fungal infections

Scientists demonstrate a new regulation mechanism for skeletal muscles

Gestational diabetes may increase offspring's heart disease risk

FAU researchers find possible cause of Parkinson’s disease in the patients’ immune system

Protective qualities of 'good cholesterol' reduce after menopause

Kite collaborates with Gadeta to develop novel gamma delta TCR therapies for various cancers

Biophysicists use infrared sensor as new method for drug discovery

WFN to highlight clean air for brain health on World Brain Day 2018

TGen opens tissue donation portal to advance DIPG research

Research project investigates snake venom treatment as antibiotic alternative for eye infections

Researchers unravel how ALL invades the central nervous system

Study identifies RNA molecules that regulate male hormones in prostate cancer

New proteomics studies help gain more insights into Alzheimer's, cancer and listeriosis

Scientists study adverse effects of carbon, silicon nanotubes and carbon nanofibers

Researchers gain more insight into how FUS protein causes ALS and FTLD

Researchers identify subtypes of retinal ganglion cells using single-cell RNA sequencing

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