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Head and neck cancers associated with genetic alterations could be sensitive to existing cancer drug

An examination of the genetic landscape of head and neck cancers indicates that while metastatic and primary tumor cells share similar mutations, recurrent disease is associated with gene alterations that could be exquisitely sensitive to an existing cancer drug.

7 Apr 2014

Research suggests NEDD9 scaffolding protein activates oncogenic signaling pathways in cancer cells, encourages metastases

Researchers from Fox Chase Cancer Center have shown that NEDD9, a scaffolding protein responsible for regulating signaling pathways in the cell, promotes the growth and spread of epithelial ovarian cancer.

7 Apr 2014

Study: Intense physiotherapy sessions have no additional benefits for chronic whiplash pain

Results of a new trial of treatments for chronic whiplash pain, published in The Lancet, suggest that expensive, intense physiotherapy sessions do not show any additional benefit over a single physiotherapy session of education and advice with phone follow-up.

7 Apr 2014

Helium ion radiotherapy provides hope for improved, accurate radiation treatment for young cancer patients

For the first time, researchers have been able to demonstrate that the use of helium ions in radiation therapy could provide accurate treatment to tumours while helping to spare healthy organs.

7 Apr 2014

Genetic screening of cancer can help doctors customize treatments in patients with melanoma

Genetic screening of cancer can help doctors customize treatments so that patients with melanoma have the best chance of beating it, according to the results of a clinical trial by researchers at the University of Pittsburgh Cancer Institute (UPCI), a partner with UPMC CancerCenter.

7 Apr 2014

Blood sample could diagnose many types of solid cancers

A blood sample could one day be enough to diagnose many types of solid cancers, or to monitor the amount of cancer in a patient's body and responses to treatment. Previous versions of the approach, which relies on monitoring levels of tumor DNA circulating in the blood, have required cumbersome and time-consuming steps to customize it to each patient or have not been sufficiently sensitive.

7 Apr 2014

Personalized treatment approach may benefit patients with common breast cancer subtype

The second-most common type of breast cancer is a very different disease than the most common and appears to be a good candidate for a personalized approach to treatment, according to a multidisciplinary team led by scientists at the University of Pittsburgh Cancer Institute (UPCI), a partner with UPMC CancerCenter.

7 Apr 2014

Treatment for opioid overdose now available for use by non-medical personnel

The U.S. Food and Drug Administration (FDA) has approved the first naloxone treatment specifically designed to be given by family members or caregivers to treat a person with opioid overdose.

4 Apr 2014

Special Tree NeuroCare Center in Romulus offers greenhouse therapy

Recovering from a brain injury involves a great deal of hard work, and some of that work includes finding ways to enjoy life again.

4 Apr 2014

Astellas, Medivation submit European Marketing Authorization Application for XTANDI capsules

Astellas Pharma Inc. and Medivation Inc. today announced the submission of a variation to amend the European Marketing Authorization Application for XTANDI® (enzalutamide) capsules for the treatment of adult men with metastatic castration-resistant prostate cancer (mCRPC) who are asymptomatic or mildly symptomatic after failure of androgen deprivation therapy and in whom chemotherapy is not yet clinically indicated.

4 Apr 2014

Lifestyle interventions may help pre-diabetics dodge risk of death from cardiovascular disease

Many research studies have shown that lifestyle interventions, such as exercise programmes or weight loss, in people with impaired glucose tolerance (those at high risk of diabetes) can prevent progression to overt type 2 diabetes. However, until now, there has been a lack of high quality, randomized controlled trial evidence to prove that lifestyle interventions prevent deaths from cardiovascular disease, such as heart attacks and stroke, in these people.

4 Apr 2014

Novartis to present early stage data on 19 investigational compounds at AACR annual meeting

Novartis announced today that early stage data on 19 investigational compounds in its oncology pipeline will be presented at the annual meeting of the American Association of Cancer Research, April 5-9, 2014 in San Diego, CA.

4 Apr 2014

Researchers identify possible way to prevent headaches of climbers

By monitoring blood flow in the brains of six climbers scaling Mount Kilimanjaro in Tanzania, German medical researchers have identified a possible way to prevent the headaches that are a common feature of altitude sickness. This work appears in the latest issue of JNIRS—Journal of Near Infrared Spectroscopy.

4 Apr 2014

Study explores relationship between genetics and lifestyle in development of AD

A global study involving more than one million people worldwide will explore the relationship between genetics and lifestyle in the development of Alzheimer's disease.

4 Apr 2014

Researchers evaluate cost-effectiveness of osteoporosis screening strategy using FRAX

In new research presented at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases today, investigators showed that an osteoporosis screening strategy using FRAX as a pre-screening tool is cost-effective if the follow up of the screening and medication adherence are optimized.

4 Apr 2014

Alteration in tumor suppressor gene TP53 plays key role early in development of bone cancer

The St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project found mutations in the tumor suppressor gene TP53 in 90 percent of osteosarcomas, suggesting the alteration plays a key role early in development of the bone cancer.

4 Apr 2014

Longer looks: New doubts about shaken baby syndrome; arresting the mentally ill; self-help therapy

A number of reexamined cases in recent years - aided by new technology and debate among medical experts - have put proponents of the (Shaken Baby Syndrome) hypothesis on the defensive.

4 Apr 2014

FDA approves expanded use Dyax’s KALBITOR in treatment of acute hereditary angioedema

Dyax Corp. today announced that the U.S. Food and Drug Administration (FDA) has approved an expansion of the indication for KALBITOR (ecallantide), a peptide inhibitor of plasma kallikrein used in the treatment of acute hereditary angioedema (HAE) attacks, to include patients 12 years of age and older.

4 Apr 2014

Cognitive dysfunction reflected in schizophrenia healthcare costs

Cognitive dysfunction has direct and indirect effects on healthcare costs in patients with schizophrenia, research suggests.

3 Apr 2014

Researchers examine risks and benefits of E-cigarettes

Some believe e-cigarettes are less harmful than smoking tobacco since e-cig vapor doesn't contain the chemicals found in tobacco smoke.

3 Apr 2014

Therapy News and Research

Head and neck cancers associated with genetic alterations could be sensitive to existing cancer drug

Research suggests NEDD9 scaffolding protein activates oncogenic signaling pathways in cancer cells, encourages metastases

Study: Intense physiotherapy sessions have no additional benefits for chronic whiplash pain

Helium ion radiotherapy provides hope for improved, accurate radiation treatment for young cancer patients

Genetic screening of cancer can help doctors customize treatments in patients with melanoma

Blood sample could diagnose many types of solid cancers

Personalized treatment approach may benefit patients with common breast cancer subtype

Treatment for opioid overdose now available for use by non-medical personnel

Special Tree NeuroCare Center in Romulus offers greenhouse therapy

Astellas, Medivation submit European Marketing Authorization Application for XTANDI capsules

Lifestyle interventions may help pre-diabetics dodge risk of death from cardiovascular disease

Novartis to present early stage data on 19 investigational compounds at AACR annual meeting

Researchers identify possible way to prevent headaches of climbers

Study explores relationship between genetics and lifestyle in development of AD

Researchers evaluate cost-effectiveness of osteoporosis screening strategy using FRAX

Alteration in tumor suppressor gene TP53 plays key role early in development of bone cancer

Longer looks: New doubts about shaken baby syndrome; arresting the mentally ill; self-help therapy

FDA approves expanded use Dyax’s KALBITOR in treatment of acute hereditary angioedema

Cognitive dysfunction reflected in schizophrenia healthcare costs

Researchers examine risks and benefits of E-cigarettes

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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