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Emergence of community-acquired infections due to ESBL-producing bacteria on the rise

The emergence of community-acquired infections, such as urinary tract infections (UTI), due to strains resistant to common antibiotics are on the rise, according to Rhode Island Hospital researchers. The study is published online in the journal Antimicrobial Resistance and Infection Control.

26 Mar 2014

FDA grants PMA for Pinnacle's Optiguide DCYL700 Fiber Optic Diffuser Series flexible fiber

Concordia Healthcare Corp. announced today that its subsidiary Pinnacle Biologics, Inc., a biopharmaceutical research and development company specializing in rare diseases, was granted U.S. Food and Drug Administration premarket supplemental approval (PMA) for its Optiguide DCYL700 Fiber Optic Diffuser Series flexible fiber.

26 Mar 2014

Study lays groundwork for PET imaging studies on human Menkes disease

Scientists at the RIKEN Center for Life Science Technologies have used PET imaging to visualize the distribution in the body of copper, which is deregulated in Menkes disease, a genetic disorder, using a mouse model. This study lays the groundwork for PET imaging studies on human Menkes disease patients to identify new therapy options.

26 Mar 2014

New approach could lead to devising alternative tools for cancer therapy

Inducing biological tissue damage with an atmospheric pressure plasma source could open the door to many applications in medicine

26 Mar 2014

Oral cancer drug improves outcomes in women with resistant gynecologic cancers

An oral cancer drug improves outcomes while minimizing side effects in women with gynecologic cancers who carry a BRCA mutation and whose disease is not responding to other therapies, suggests preliminary research.

26 Mar 2014

Adaptimmune awarded £2.1 million grant to expedite development of engineered T cell therapy

Adaptimmune today announced that it has been awarded a grant of £2.1 million from the Biomedical Catalyst Fund, managed by the UK’s innovation agency the Technology Strategy Board and the Medical Research Council. The prestigious award will expedite the development of Adaptimmune’s second engineered T cell therapy programme into the clinic in triple negative breast cancer.

26 Mar 2014

Report: Prescription barriers more likely in exchange plans

The analysis by Avalere Health says that consumers who purchased health law coverage are more likely to have to get prior authorization, among other requirements, when filling prescriptions.

26 Mar 2014

ZS Pharma starts patient enrollment in ZS-9 Phase 3 trial for treatment of hyperkalemia

ZS Pharma, a specialty pharmaceutical company developing novel treatments for kidney, cardiovascular and liver disorders, today announced that it has begun enrolling patients in ZS004, its second Phase 3 clinical trial of ZS-9, a novel investigational treatment for hyperkalemia.

25 Mar 2014

BIND Therapeutics reports revenue of $2.1 million for fourth quarter 2013

BIND Therapeutics, Inc., a clinical-stage nanomedicine platform company developing targeted and programmable therapeutics called AccurinsTM, today reported financial results for the fourth quarter and year-ended December 31, 2013.

25 Mar 2014

Genable Technologies, Spark Therapeutics to advance novel therapy for rare form of retinitis pigmentosa

Spark Therapeutics and Genable Technologies announced today that they have entered into a collaboration agreement for Genable's lead therapeutic to treat rhodopsin-linked autosomal dominant retinitis pigmentosa (RHO adRP), GT038.

25 Mar 2014

Radiation therapy fights cancer in more ways than one

Radiation therapy fights cancer in more ways than one. Not only does it force cancer cells to self-destruct, but several studies demonstrate that it also activates the immune system to attack tumor cells.

25 Mar 2014

Researchers develop mathematical model that provides insights about molecular mechanisms behind virus assembly

Mathematicians at the University of York have joined forces with experimentalists at the University of Leeds to take an important step in discovering how viruses make new copies of themselves during an infection.

25 Mar 2014

High-volume medical centers improve gynecologic cancer survival

Women with ovarian and other gynecologic cancers live significantly longer when they receive care at hospitals that treat a large number of patients with these conditions, according to research on more than 850,000 women.

25 Mar 2014

XBP1 gene plays pivotal role in the growth and progression of triple negative breast cancer

Scientists from Weill Cornell Medical College and Houston Methodist have found that a gene previously unassociated with breast cancer plays a pivotal role in the growth and progression of the triple negative form of the disease, a particularly deadly strain that often has few treatment options. Their research, published in this week's Nature, suggests that targeting the gene may be a new approach to treating the disease.

25 Mar 2014

$Fracture liaison services effective in identifying, treating older adults who suffer fragility fracture$

Fracture liaison services effective in identifying, treating older adults who suffer fragility fracture

Studies have shown that anyone age 50 or older who suffers a fragility fracture - a bone break sustained in a fall from a standing height or less - is two to five times more likely to experience a second fracture than someone who hasn't had one. The odds that a person who's suffered two such fractures will have a third are even higher.

25 Mar 2014

Marina Cavazzana, Adrian J. Thrasher honored with Pioneer Award for gene therapy

Marina Cavazzana, MD, PhD, Paris Descartes University, France and Adrian J. Thrasher, MD, PhD, University College London Institute of Child Health, UK, have been honored with the Pioneer Award for basic and clinical gene therapy for immunodeficiency disorders.

25 Mar 2014

CytRx initiates Phase 3 clinical trial to evaluate efficacy of aldoxorubicin in STS patients

CytRx Corporation (Nasdaq: CYTR), a biopharmaceutical research and development company specializing in oncology, today announced it has initiated a pivotal global Phase 3 clinical trial to evaluate the efficacy and safety of aldoxorubicin as a second-line treatment for patients with soft tissue sarcoma (STS) under a Special Protocol Assessment with the FDA.

25 Mar 2014

Treatment with natalizumab in patients with MS appears linked with JC virus infection

Treatment with natalizumab in patients with multiple sclerosis (MS) appears linked with JC virus (JCV) infection, which can lead to a rare and often fatal demyelinating disease of the central nervous system called progressive multifocal leukoencephalopathy (PML) that destroys the myelin that protects nerve cells.

25 Mar 2014

Antibiotics for UTI often taken before, after incontinence surgery

One in four women undergoing surgery for urinary incontinence has recently taken antibiotics for a urinary tract infection, a large population-based study shows.

24 Mar 2014

‘Residual risk’ concern for treated Japanese hypertension patients

Physicians should be alert to other sources of cardiovascular risk in patients with hypertension, even if they are receiving optimal antihypertensive treatment, say Japanese researchers.

24 Mar 2014

Therapy News and Research

Emergence of community-acquired infections due to ESBL-producing bacteria on the rise

FDA grants PMA for Pinnacle's Optiguide DCYL700 Fiber Optic Diffuser Series flexible fiber

Study lays groundwork for PET imaging studies on human Menkes disease

New approach could lead to devising alternative tools for cancer therapy

Oral cancer drug improves outcomes in women with resistant gynecologic cancers

Adaptimmune awarded £2.1 million grant to expedite development of engineered T cell therapy

Report: Prescription barriers more likely in exchange plans

ZS Pharma starts patient enrollment in ZS-9 Phase 3 trial for treatment of hyperkalemia

BIND Therapeutics reports revenue of $2.1 million for fourth quarter 2013

Genable Technologies, Spark Therapeutics to advance novel therapy for rare form of retinitis pigmentosa

Radiation therapy fights cancer in more ways than one

Researchers develop mathematical model that provides insights about molecular mechanisms behind virus assembly

High-volume medical centers improve gynecologic cancer survival

XBP1 gene plays pivotal role in the growth and progression of triple negative breast cancer

Fracture liaison services effective in identifying, treating older adults who suffer fragility fracture

Marina Cavazzana, Adrian J. Thrasher honored with Pioneer Award for gene therapy

CytRx initiates Phase 3 clinical trial to evaluate efficacy of aldoxorubicin in STS patients

Treatment with natalizumab in patients with MS appears linked with JC virus infection

Antibiotics for UTI often taken before, after incontinence surgery

‘Residual risk’ concern for treated Japanese hypertension patients

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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