Translation News and Research

RSS

Alnylam presents positive ongoing phase 2 open-label extension data for Patisiran and Revusiran

Alnylam Pharmaceuticals, Inc. has announced new results from its ongoing Phase 2 open-label extension (OLE) studies with patisiran and revusiran, investigational RNAi therapeutics targeting transthyretin (TTR) for the treatment of TTR-mediated amyloidosis (ATTR amyloidosis).

3 Nov 2015

ISCT launches publication and reference guide on Use of Unproven Cellular Therapies

The International Society for Cellular Therapy, the global society of clinicians, researchers, regulators, technologists, and industry partners dedicated to the translation of cellular therapy into safe and effective therapies to improve patients’ lives, today announces the launch of its publication and reference guide on the Use of Unproven Cellular Therapies.

31 Oct 2015

Scientists identify new jelly-like properties of essential proteins that lead to serious diseases

Scientists at the University of Cambridge have identified a new property of essential proteins which, when it malfunctions, can cause the build up, or 'aggregation', of misshaped proteins and lead to serious diseases.

31 Oct 2015

New magnetic field delivery method could help treat traumatic brain injury

Treating traumatic brain injury (TBI) using stem cell therapy is an important area of current research. However, injecting stem cells into the central nervous system has serious drawbacks, including intracranial hemorrhage and cells failing to reach TBI-affected areas of the brain.

30 Oct 2015

New single-agent phototherapy system may form valuable new tool to combat cancer

Researchers at Oregon State University today announced an important advance in the field of cancer imaging and phototherapy, using a single-agent system that may ultimately change the efficacy of cancer surgery and treatment around the world.

30 Oct 2015

Endocrine Society to host Congressional briefing on November 4 to combat diabetes epidemic

The Endocrine Society is hosting a Congressional briefing on November 4 to examine policies to help the 29 million Americans who have diabetes and the 86 million who are likely to develop the disease.

28 Oct 2015

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Four tiny segments of RNA appear to play critical roles in controlling cholesterol and triglyceride metabolism. In their report receiving advance online publication in Nature Medicine, a Massachusetts General Hospital-based research team describes finding how these microRNAs could reduce the expression of proteins playing key roles in the generation of beneficial HDL cholesterol, the disposal of artery-clogging LDL cholesterol, control of triglyceride levels and other risk factors of cardiovascular disease.

27 Oct 2015

New generation of RNAscope products for RNA-biomarker analysis in FFPE tissue released

Advanced Cell Diagnostics Inc. (ACD), the market leader in tissue-based RNA analysis tools for molecular pathology, has announced the release of its next version RNAscope® in situ hybridization (ISH) assay – RNAscope 2.5.

From Advanced Cell Diagnostics 21 Oct 2015

Elsevier chosen to publish AWHONN's JOGNN and Nursing for Women's Health

Elsevier, a world-leading provider of scientific, technical, and medical information products and services, and The Association of Women's Health, Obstetric and Neonatal Nurses have announced that Elsevier will publish AWHONN's official publications, Journal of Obstetric, Gynecologic & Neonatal Nursing and Nursing for Women's Health, beginning with the 2016 volumes.

19 Oct 2015

Nanodiamonds may improve outcomes for patients undergoing root canals

People undergoing root canals may have gained a powerful, if tiny, new ally. Researchers from the UCLA School of Dentistry have found that using nanodiamonds to fortify a material used in the procedure could significantly improve outcomes for patients.

19 Oct 2015

Primary care physicians often under- or over-estimate stroke and bleeding risk in AF patients

Patients with atrial fibrillation (AF) have an increased risk for stroke and are often prescribed oral anticoagulation (OAC) therapy. OAC therapy can prevent disastrous strokes, but at the expense of increased bleeding risks. There are now well-established guidelines to assess the risk of stroke and bleeding in AF patients to determine whether OAC is needed.

19 Oct 2015

Set of genes identified in human genome essential for survival, proliferation of human cell lines

Using two complementary analytical approaches, scientists at Whitehead Institute and Broad Institute of MIT and Harvard have for the first time identified the universe of genes in the human genome essential for the survival and proliferation of human cell lines or cultured human cells.

16 Oct 2015

Square Roots announces acquisition of Fitzgerald Analytics

Square Roots, a life sciences company focused on pregnancy and the healthy formation of life, announced that it has acquired Fitzgerald Analytics, a leading analytics and data science firm. The cash and stock purchase is central to Square Roots' strategy to develop evidence-based solutions that improve maternal health in the United States.

15 Oct 2015

Poorly-designed animal study threatens validity of preclinical research

Badly designed studies may lead to the efficacy of drugs being overestimated and money being wasted on trials that prove fruitless, according to new a study from McGill University in Canada.

15 Oct 2015

Graft properties affect knee ligament surgery outcome more than surgical technique

In anterior cruciate ligament (ACL) reconstruction, graft stiffness and pre-strain play a more vital role than the choice of surgical technique, indicates a new study from the University of Eastern Finland. The study developed a computational 3D model of the knee joint, which can be used in the prevention of osteoarthritis (OA), specifically OA resulting from trauma.

15 Oct 2015

Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

Researchers from Isis Pharmaceuticals (Carlsbad, CA) and Prysis Biotechnologies (Pudong, Shanghai, China) have demonstrated proof-of-concept for using a sense oligonucleotide to undo the effects of an antisense drug, an antithrombotic agent in this novel study.

14 Oct 2015

New microscope technology may help surgeons work with greater accuracy

Researchers at the University of Arizona have developed a prototype of a new microscope technology that could help surgeons work with a greater degree of accuracy. The new technology, call augmented microscopy, overlays images depicting diagnostic information such as blood flow and cancerous tissue over real images of blood vessels and other tissues and structures being viewed in the microscope.

8 Oct 2015

Three researchers recognised for their contributions to Australian medical research

Three top Walter and Eliza Hall Institute researchers have been recognised for their contributions to Australian medical research, with their election as fellows of the Australian Academy of Health and Medical Sciences.

7 Oct 2015

Cornell University, MSKCC jointly open new $10 million Center of Cancer Nanotechnology Excellence

Cornell University, in partnership with Memorial Sloan Kettering Cancer Center, is opening a new $10 million Center of Cancer Nanotechnology Excellence that brings together scientists, engineers, biologists and physicians to develop and translate new cancer care applications based on nanotechnology.

30 Sep 2015

Brain prosthesis may help individuals suffering from memory loss

Researchers at USC and Wake Forest Baptist Medical Center have developed a brain prosthesis that is designed to help individuals suffering from memory loss.

30 Sep 2015

Translation News and Research

Alnylam presents positive ongoing phase 2 open-label extension data for Patisiran and Revusiran

ISCT launches publication and reference guide on Use of Unproven Cellular Therapies

Scientists identify new jelly-like properties of essential proteins that lead to serious diseases

New magnetic field delivery method could help treat traumatic brain injury

New single-agent phototherapy system may form valuable new tool to combat cancer

Endocrine Society to host Congressional briefing on November 4 to combat diabetes epidemic

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

New generation of RNAscope products for RNA-biomarker analysis in FFPE tissue released

Elsevier chosen to publish AWHONN's JOGNN and Nursing for Women's Health

Nanodiamonds may improve outcomes for patients undergoing root canals

Primary care physicians often under- or over-estimate stroke and bleeding risk in AF patients

Set of genes identified in human genome essential for survival, proliferation of human cell lines

Square Roots announces acquisition of Fitzgerald Analytics

Poorly-designed animal study threatens validity of preclinical research

Graft properties affect knee ligament surgery outcome more than surgical technique

Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

New microscope technology may help surgeons work with greater accuracy

Three researchers recognised for their contributions to Australian medical research

Cornell University, MSKCC jointly open new $10 million Center of Cancer Nanotechnology Excellence

Brain prosthesis may help individuals suffering from memory loss

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News