Blood News and Research

RSS

Using CRISPR-Cas9 genome editing to correct mutation responsible for sickle cell disease

Genome editing using the CRISPR-Cas9 system has tremendous promise for therapeutic correction of genetic errors in human cells. Prior to adoption as a medical therapeutic, safety concerns relating to off-target effects must be minimized to mitigate risks that may arise from the unintended action of this system at sites similar, but not identical, to the desired gene target site.

From Integrated DNA Technologies 10 Aug 2018

Innovative program by community health centers increases colorectal cancer screening

An innovative program in community health centers to mail free colorectal cancer screening tests to patients' homes led to a nearly 4 percentage point increase in CRC screening, compared to clinics without the program, according to a Kaiser Permanente study published today in JAMA Internal Medicine.

10 Aug 2018

Researchers describe underlying mechanisms of congestive heart failure

Congestive heart failure is a terminal disease that affects nearly 6 million Americans. Yet its management is limited to symptomatic treatments because the causal mechanisms of congestive heart failure -- including its most common form, ischemic cardiomyopathy -- are not known.

10 Aug 2018

Researchers study use of MRI-guided focused ultrasound to open blood-brain barrier

In the first such clinical trial in the United States, physician-scientists with the University of Maryland School of Medicine are investigating the use of MRI-guided focused ultrasound to open the blood-brain barrier.

10 Aug 2018

Ketogenic diet may raise risk of diabetes finds study

Ketogenic diet is a form of diet that consists of high fat and protein content and very low carbohydrate content. It has been known to promote weight loss and is considered to healthy. It has been adopted by many people globally.

10 Aug 2018

New discovery could pave way for improved leukemia treatment

Previous research has revealed that patients with acute myeloid leukemia who also have a particular mutation in a gene called NPM1 have a higher rate of remission with chemotherapy. About one-third of leukemia patients possess this favorable mutation, but until now, how it helps improve outcomes has remained unknown.

9 Aug 2018

RCSI and Bayer collaborate to improve treatments for people with hemophilia

RCSI and Bayer have today announced a research collaboration that aims to improve treatments for people with severe haemophilia.

9 Aug 2018

Older kidney disease patients on dialysis have higher dementia risk

Older kidney disease patients who are sick enough to require the blood-filtering treatment known as dialysis are at high risk of dementia, including Alzheimer's disease, according to a study led by scientists at Johns Hopkins Bloomberg School of Public Health.

9 Aug 2018

Young adults who binge drink more likely to have cardiovascular risk factors

You might want to think before you go out drinking again tonight. Research by Mariann Piano, senior associate dean of research at Vanderbilt University School of Nursing, has found that young adults who frequently binge drink were more likely to have specific cardiovascular risk factors such as higher blood pressure, cholesterol and blood sugar at a younger age than non-binge drinkers.

9 Aug 2018

Estrogen may protect against heart failure-related depression

Estrogen may protect against heart failure-related depression by preventing the production of inflammation-causing chemicals in the brain. The study is published ahead of print in the American Journal of Physiology - Heart and Circulatory Physiology.

9 Aug 2018

Lax oversight leaves surgery center regulators and patients in the dark

The first man died in April 2014. Another died later that month. Then on July 18 of that year, a woman was rushed to a hospital where she was told she was lucky to be alive.

9 Aug 2018

New 3D-printed device could help spinal cord injury patients regain some function

Engineers and medical researchers at the University of Minnesota have teamed up to create a groundbreaking 3D-printed device that could someday help patients with long-term spinal cord injuries regain some function.

9 Aug 2018

Researchers describe new class of potent inhibitors against amyloid plaques

Effective therapeutics to counteract the formation of amyloid plaques in Alzheimer's disease and type 2 diabetes are not yet available.

9 Aug 2018

RNA and DNA sequencing platform matches broader swath of drugs to late-stage cancer patients

A comprehensive RNA and DNA sequencing platform benefits late-stage and drug-resistant multiple myeloma patients by determining which drugs would work best for them, according to results from a clinical trial published in JCO Precision Oncology in August.

9 Aug 2018

Proof-of-concept technology using nanoparticles could offer new approach for oral medications

Since the development of insulin to manage diabetes, pharmacists have longed to create an insulin pill. Past attempts have failed because insulin does not survive the harsh conditions of the gastro-intestinal system and cannot easily cross the GI wall.

9 Aug 2018

Atlas of the nervous system provides new clues about origin of neurological diseases

Researchers at Karolinska Institutet have created a systematic and detailed map of the cell types of the mouse nervous system.

9 Aug 2018

Cancer cells release biological 'drones' to assist in the fight against immune system

Cancer cells are more than a lump of cells growing out of control; they participate in active combat with the immune system for their own survival. Being able to evade the immune system is a hallmark of cancer.

9 Aug 2018

Scientists turn to C. elegans for new model of peripheral neuropathy

Studying transthyretin amyloidoses - a group of progressive nerve and cardiac degenerative diseases caused by the buildup of misfolded transthyretin proteins in the body - has long been hampered by the lack of animal models of the disease.

9 Aug 2018

Responsive parenting intervention promotes healthy weight in young children

An intervention designed to promote healthy growth that taught first-time moms how to respond with age-appropriate responses to their babies' needs resulted in children having lower body mass indexes when they were three years old.

9 Aug 2018

Researchers modify nanoparticles to improve their uptake in gastrointestinal tract

Nanoparticles show great promise as diagnostic tools and drug delivery agents. The tiny particles, which scientists can modify with drugs, dyes or targeting molecules, can travel in the circulation and squeeze through small spaces into cells and tissues.

9 Aug 2018

Blood News and Research

Using CRISPR-Cas9 genome editing to correct mutation responsible for sickle cell disease

Innovative program by community health centers increases colorectal cancer screening

Researchers describe underlying mechanisms of congestive heart failure

Researchers study use of MRI-guided focused ultrasound to open blood-brain barrier

Ketogenic diet may raise risk of diabetes finds study

New discovery could pave way for improved leukemia treatment

RCSI and Bayer collaborate to improve treatments for people with hemophilia

Older kidney disease patients on dialysis have higher dementia risk

Young adults who binge drink more likely to have cardiovascular risk factors

Estrogen may protect against heart failure-related depression

Lax oversight leaves surgery center regulators and patients in the dark

New 3D-printed device could help spinal cord injury patients regain some function

Researchers describe new class of potent inhibitors against amyloid plaques

RNA and DNA sequencing platform matches broader swath of drugs to late-stage cancer patients

Proof-of-concept technology using nanoparticles could offer new approach for oral medications

Atlas of the nervous system provides new clues about origin of neurological diseases

Cancer cells release biological 'drones' to assist in the fight against immune system

Scientists turn to C. elegans for new model of peripheral neuropathy

Responsive parenting intervention promotes healthy weight in young children

Researchers modify nanoparticles to improve their uptake in gastrointestinal tract

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Latest News