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RNAi-based screening offers MPM treatment hope

Research using RNA interference-based screening has identified several potential targets for the treatment of malignant pleural mesothelioma.

31 Jan 2014

AbbVie's global sales reduce 1.8% to $5.111B in fourth quarter 2013

AbbVie today announced financial results for the fourth quarter and full year ended Dec. 31, 2013.

31 Jan 2014

Researchers pinpoint neural circuitry that promotes stress-induced anxiety

According to the National Institute of Mental Health, over 18 percent of American adults suffer from anxiety disorders, characterized as excessive worry or tension that often leads to other physical symptoms. Previous studies of anxiety in the brain have focused on the amygdala, an area known to play a role in fear.

31 Jan 2014

Vitamin A may help keep immune system under control for autoimmune and transplant patients

The same form of Vitamin A used by teenagers to combat acne might offer benefits that are more than skin deep. That's because an international team of researchers have found that it may also help keep the immune system under control for people with autoimmune disorders or those who have received transplants.

31 Jan 2014

More than 1/3 of women experience hot flashes for 10 years after menopause

A team of researchers from the Perelman School of Medicine at the University of Pennsylvania has found that moderate to severe hot flashes continue, on average, for nearly five years after menopause, and more than a third of women experience moderate/severe hot flashes for 10 years or more after menopause.

31 Jan 2014

Core stabilization exercise in stroke patients could be enhanced by real-time video feedback

About 80% of stroke survivors experience hemiparesis, which causes weakness or the inability to move one side of the body. Core stabilization exercise to improve postural stability and independent walking in chronic hemiparetic stroke patients could be enhanced by real-time video feedback, report researchers in Restorative Neurology and Neuroscience.

31 Jan 2014

Prediction models can be useful for heart team to determine best treatment strategy

Detailed prediction models that project long-term patient mortality following percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) surgery can be useful for the heart team when determining the best treatment strategy for individual patients, according to a study in the February 2014 issue of The Annals of Thoracic Surgery.

31 Jan 2014

Children with peanut allergies could benefit from oral immunotherapy treatment

Children and adolescents with peanut allergies could benefit from treatment with oral immunotherapy (OIT), in which peanut protein is consumed in increasingly larger amounts on a regular basis to build up tolerance, according to a phase 2 trial published in The Lancet.

31 Jan 2014

Researchers identify components of C. diff bacteria that can be used to develop better treatment

Rhode Island Hospital researchers have identified components in Clostridium difficile (C. diff) that may lead to new diagnostic tools, and ultimately more timely and effective treatment for this often fatal infection. C. diff is a spore-forming bacterium that causes severe diarrhea and is responsible for 14,000 deaths annually in the U.S. The study is published online in advance of print in the Journal of Molecular Diagnostics.

31 Jan 2014

NeoGenomics validates and launches series of NeoTYPE cancer profiling tests

NeoGenomics, Inc., a leading provider of cancer-focused genetic and molecular testing services, announced today that it has validated and launched a series of NeoTYPE cancer profiling tests covering 22 different categories of cancer. Each of these tests is designed to investigate the most common and actionable genomic abnormalities reported for that particular tumor.

30 Jan 2014

Not all children, young adults treated achieve long-term relief from symptoms of anxiety

Fewer than one in two children and young adults treated for anxiety achieve long-term relief from symptoms, according to the findings of a study by investigators from the Johns Hopkins Children's Center and five other institutions.

30 Jan 2014

Alexion Pharmaceuticals reports full year 2013 GAAP and non-GAAP financial results

Alexion Pharmaceuticals, Inc. today announced financial results for the quarter and year ended December 31, 2013. For the three months ended December 31, 2013, Alexion Pharmaceuticals, Inc. ("Alexion" or the "Company") reported net product sales of Soliris® (eculizumab) of $441.9 million, compared to $320.5 million for the same period in 2012.

30 Jan 2014

AVEO Oncology, Astellas Pharma decide to discontinue BATON breast cancer clinical trial

AVEO Oncology today announced that AVEO and Astellas Pharma Inc. have jointly decided to discontinue the BATON (Biomarker Assessment of Tivozanib in ONcology) breast cancer clinical trial, a Phase 2 study in patients with locally recurrent or metastatic triple negative breast cancer (TNBC), due to insufficient enrollment.

30 Jan 2014

Geranium plant extracts prevent HIV-1 from invading human cells

Extracts of the geranium plant Pelargonium sidoides inactivate human immunodeficiency virus type 1 (HIV-1) and prevent the virus from invading human cells. In the current issue of "PLOS ONE", scientists from the Helmholtz Zentrum München report that these extracts represent a potential new class of anti-HIV-1 agents for the treatment of AIDS.

30 Jan 2014

CTI announces initiation of pacritinib Phase 2 trial in AML patients with FLT3 mutations

Cell Therapeutics, Inc. today announced the initiation of an international cooperative group Phase 2 clinical trial of pacritinib in adult patients with relapsed acute myeloid leukemia (AML) with mutations of the FLT3 gene. Mutation of the FLT3 gene is found in approximately one-third of AML patients and is an independent risk factor for poor prognosis.

30 Jan 2014

Findings could improve clinical management of patients with breast tissue abnormalities

Contrary to existing understanding, long-term follow-up of patients with two types of breast tissue abnormalities suggests that both types of abnormalities have the same potential to progress to breast cancer, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research. Findings from this study could improve clinical management of patients with breast tissue abnormalities.

30 Jan 2014

Scientists receive new awards from CIRM to advance revolutionary stem cell science in medicine

Scientists from UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have received new awards from the California Institute of Regenerative Medicine (CIRM), the state stem cell research agency, that will forward revolutionary stem cell science in medicine.

30 Jan 2014

TCGA Research Network identify new potential therapeutic targets for major form of bladder cancer

Investigators with The Cancer Genome Atlas (TCGA) Research Network have identified new potential therapeutic targets for a major form of bladder cancer, including important genes and pathways that are disrupted in the disease.

30 Jan 2014

Patients receiving APBI after breast-conserving surgery show excellent tumor control, breast cosmesis

Long-term outcomes of breast cancer patients receiving adjuvant accelerated partial breast irradiation after breast-conserving surgery show excellent tumor control and breast cosmesis (cosmetic outcomes) with minimal late toxicity, according to a study published in the February 1, 2014 print edition of the International Journal of Radiation Oncology.

30 Jan 2014

Findings on molecular defects behind bladder cancer may pave way for new, targeted treatments

The once sketchy landscape of the molecular defects behind bladder cancer now resembles a road map to new, targeted treatments thanks to the unified efforts of scientists and physicians at 40 institutions.

30 Jan 2014

Therapy News and Research

RNAi-based screening offers MPM treatment hope

AbbVie's global sales reduce 1.8% to $5.111B in fourth quarter 2013

Researchers pinpoint neural circuitry that promotes stress-induced anxiety

Vitamin A may help keep immune system under control for autoimmune and transplant patients

More than 1/3 of women experience hot flashes for 10 years after menopause

Core stabilization exercise in stroke patients could be enhanced by real-time video feedback

Prediction models can be useful for heart team to determine best treatment strategy

Children with peanut allergies could benefit from oral immunotherapy treatment

Researchers identify components of C. diff bacteria that can be used to develop better treatment

NeoGenomics validates and launches series of NeoTYPE cancer profiling tests

Not all children, young adults treated achieve long-term relief from symptoms of anxiety

Alexion Pharmaceuticals reports full year 2013 GAAP and non-GAAP financial results

AVEO Oncology, Astellas Pharma decide to discontinue BATON breast cancer clinical trial

Geranium plant extracts prevent HIV-1 from invading human cells

CTI announces initiation of pacritinib Phase 2 trial in AML patients with FLT3 mutations

Findings could improve clinical management of patients with breast tissue abnormalities

Scientists receive new awards from CIRM to advance revolutionary stem cell science in medicine

TCGA Research Network identify new potential therapeutic targets for major form of bladder cancer

Patients receiving APBI after breast-conserving surgery show excellent tumor control, breast cosmesis

Findings on molecular defects behind bladder cancer may pave way for new, targeted treatments

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

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Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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