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Scientists discover how cancer-targeting 'Natural Killer' cells are fueled in the body

Scientists have just made an important discovery as to how cancer-targeting 'Natural Killer' cells are fueled in the body, which has significant implications for related therapies.

14 Jun 2018

Researchers show feasibility of stem cell-derived organoids for developing gene therapy vectors

A new study that compared six of the most promising adeno-associated viral gene therapy vectors in human retinal organoid models showed clear distinctions in the efficiency of gene transfer to both retinal pigment epithelial and photoreceptor cells.

14 Jun 2018

Researchers produce snapshots of the cell's 'protein factories'

Berlin-based researchers have produced snapshots of the 'protein factories' of the cell. Their findings could set us on the path towards a new class of antibiotics.

14 Jun 2018

Genetically engineered bacteria shows promise as new treatment for constipation

Genetically engineered bacteria are showing promise as a new treatment for constipation, researchers at the Mayo Clinic Center for Individualized Medicine have discovered in a mouse study.

14 Jun 2018

New studies on fat cell filling, history of biochemistry, and ketogenic diet

There's more than one type of fat cell. Besides the white fat that stores triglycerides in lipid droplets in preparation for lean times later, mammals also have heat-generating brown fat, which acts more like a radiator than a storage closet.

14 Jun 2018

Scientists discover unique feature in the 'antennae' of light-sensing neurons

Scientists at Baylor College of Medicine and Radboud University Medical Center in the Netherlands have discovered that the antennae-like structures on light-sensing neurons, called photoreceptors, have a unique feature not observed in the 'antennae' or cilia of other types of cells.

14 Jun 2018

Music therapy shows promise for improving lives of people with sickle cell disease

A new study published in the Journal of Music Therapy reveals promising findings for the application of improvisational music therapy in assuaging the multidimensional acute pain of adult patients with sickle cell disease.

14 Jun 2018

Study opens new potential avenue for treating ovarian cancer

Researchers at Houston Methodist Research Institute and The University of Texas MD Anderson Cancer Center have found a prescription drug, Calcitriol, approved by the Food and Drug Administration for the treatment of calcium deficiency and kidney diseases, may increase the likelihood of surviving ovarian cancer.

14 Jun 2018

Scientists develop method to determine metabolic activity of neural networks

During the last decade, neurobiologists's attention has been focused on the study of the functioning of neural networks rather than single nerve cells.

14 Jun 2018

New study shows how vitamin A effectively supports lung immunity against TB

Scientists at Trinity College Dublin and St James's Hospital, Dublin, have discovered how vitamin A drives the lung immune system to deal with tuberculosis

14 Jun 2018

Non-invasive optical imaging detects early molecular signatures of disease

Chronic conditions including obesity, cardiovascular disease, and cancer often begin with early, subtle changes in cellular metabolism.

13 Jun 2018

Extensive lipidomics studies reveal signatures of metabolic health and disease

Scientists from EPFL and the University of Wisconsin-Madison have carried out one of the most extensive lipidomics studies to date, connecting almost 150 different lipid species to their respective genetic regulators, revealing signatures of metabolic health and disease.

13 Jun 2018

Cleveland Clinic receives $3.7 million grant from AHA for atrial fibrillation research

The American Heart Association has awarded Cleveland Clinic a $3.7 million grant for atrial fibrillation research. The four-year, competitive award will support three synergistic projects aimed at improving outcomes for patients with atrial fibrillation, a common heart rhythm abnormality.

13 Jun 2018

Researchers develop biomimetic nanosystem to deliver therapeutic proteins to target tumors

A team of Penn State researchers has developed a biomimetic nanosystem to deliver therapeutic proteins to selectively target cancerous tumors.

13 Jun 2018

Study finds higher response to anti-PD1 immunotherapy in older melanoma patients

With each decade of life, the likelihood of progression of melanoma after treatment with anti-PD1 immunotherapy decreased by 13 percent.

13 Jun 2018

Study unravels how nuclear pore complexes transport mRNAs out of the nucleus

Standing guard between a cell's nucleus and its main chamber, called the cytoplasm, are thousands of behemoth protein structures called nuclear pore complexes, or NPCs.

13 Jun 2018

Waste-disposal system of cell appears to play key role in spread of Alzheimer's disease

The waste-disposal system in a cell can spread harmful protein aggregates between neurons in the brain in Alzheimer's disease, according to researchers at Linköping University, Sweden.

13 Jun 2018

New test can identify ICU patients at greatest risk of secondary infections

Patients in intensive care units are at significant risk of potentially life-threatening secondary infections, including from antibiotic-resistant bacteria such as MRSA and C. difficile.

13 Jun 2018

Researchers develop ground-breaking approach for treatment of pneumonia

A chance conversation between researchers at Queen's University Belfast led to their combined expertise in developing a ground-breaking approach for the treatment of pneumonia.

13 Jun 2018

Older melanoma patients fare better on immune checkpoint blockade therapy

Patient age correlates with response to immunotherapy in melanoma and depleting regulatory T cells in young patients may have a therapeutic potential to enhance response in younger patients, according to research from The Wistar Institute. Study results were published online in Clinical Cancer Research.

13 Jun 2018