Genes News and Research

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Researchers discover how hepatic-C virus evades immune system in acute and chronic infections

Researchers at Johns Hopkins have uncovered how a majority of the genetic changes in the hepatic-C virus, the most common cause of liver disease, allow it to evade the body's immune system during infection.

10 Jun 2005

Experimental drug works best in combination with older remedy for Alzheimer's disease and other dementias

An experimental drug combined with an already-popular memory-enhancing compound may further delay memory loss in patients with Alzheimer's disease and other dementias, Johns Hopkins University scientists, in collaboration with researchers from University of North Carolina, have found.

9 Jun 2005

Accumulation of genetic changes is not solely determined by natural selection

New data suggest that the accumulation of genetic changes is not solely determined by natural selection. A study by University of Chicago researchers contradicts conventional theory by showing that the percentage of mutations accepted in evolution is also strongly swayed by the speed at which new mutations arrive at a gene: the faster the speed of new mutations, the greater the percentage of those mutations accepted.

9 Jun 2005

Study of glial cells in the roundworm C. elegans may provide insight into a variety of human brain diseases

The key to understanding our brains may lie within a one-millimeter long worm, new research from Rockefeller University indicates. Reporting in the June issue of Developmental Cell, Shai Shaham, Ph.D., and graduate student Elliot Perens use the roundworm, C. elegans, to investigate the mysterious glial cell, which makes up 90 percent of the human brain and, when it malfunctions, can contribute to diseases like Parkinson's disease and schizophrenia.

9 Jun 2005

MicroRNAs play an important role in human cancer

Over the past few years, scientists have discovered that a new class of genetic regulators called "microRNAs" influences normal human growth and development. Now, researchers have found that microRNAs also play an important role in human cancer. The findings are published in today's issue of the journal Nature (June 9).

9 Jun 2005

New study shows tiny RNAs intimately associated with cancer

In discoveries that may open a new chapter in understanding and diagnosing cancer, Howard Hughes Medical Institute (HHMI) investigators and their colleagues have established that tiny microRNAs provide a novel genetic route to the initiation of some forms of cancer.

9 Jun 2005

Researchers link aberrant 'microRNA' expression to human cancer

8 Jun 2005

New understanding of microRNAs

Ribonucleic acid, or RNA, has long been thought to be important only to translate a gene's DNA into the proteins that are cells' workhorses. But new evidence shows that tiny bits of RNA not used to make proteins actually play central roles in normal biology and in the development of cancers.

8 Jun 2005

Study is the first to identify involvement of chromosome 21 in developmental regression autism

A new Cincinnati Children's Hospital Medical Center study links regions of two chromosomes to susceptibility for a type of autism characterized by regression in development. Developmental regression can include the loss of previously acquired language, social skills or both.

8 Jun 2005

New bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity

Scientists at Lawrence Livermore National Laboratory (LLNL) and the Linnaeus Centre for Bioinformatics (LCB) at Uppsala University in Sweden have developed a new bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity.

8 Jun 2005

Girls who can't orgasm can blame it on their genes

Scientists have discovered that an inability in some women to acheive an orgasm may have a genetic cause.

8 Jun 2005

Diversity of HLA genotypes in humans is shaped to a significant degree by pathogens

The great physical diversity that evolution has forged in human beings is in evidence wherever we look, but the genes exhibiting the greatest diversity at the DNA level happen to function in a wholly invisible process: immunity. Genes encoding the Human Leukocyte Antigen (HLA) proteins are among the most diverse in the human genome, and scientists have proposed a number of hypotheses to explain why.

6 Jun 2005

Gene therapy for arthritis is both feasible and safe

Gene therapy for arthritis and other non-terminal, debilitating conditions and diseases is both feasible and safe, report researchers who conducted the world's first such test on the approach in patients with advanced rheumatoid arthritis.

6 Jun 2005

Statisticians learn how to analyze huge quantities of genetic data

In a conceptual breakthrough, a team of researchers led by statisticians at the Harvard School of Public Health (HSPH) has figured out how to analyze huge quantities of genetic data, surpassing the capabilities of traditional techniques and speeding the quest for understanding the genetic basis of complex diseases such as asthma and diabetes.

6 Jun 2005

Major advances in the global fight against eye disease

Now research offering a better understanding of the genetics controlling endemic eye diseases will be advanced by an international collaboration between Cardiff University’s School of Optometry and Vision Sciences and the Department of Opthalmology, Kyoto Prefectural University of Medicine, Japan.

6 Jun 2005

Intelligence and genetic disease link

A new study by the University of Utah on Ashkenazi Jews has suggested an unusual link between their genetic diseases and their higher intellectual ability.

6 Jun 2005

Toxic chemicals that poisoned your great-grandparents may also damage your health

New U.S. research is suggesting that chemicals can change the way genes work and that toxic chemicals that poisoned your great-grandparents may also damage your health.

5 Jun 2005

Gene research may help explain how adorable children become surly teenagers

University of Utah researchers showed that a fruit fly gene is crucial for determining when juveniles begin to mature into adults, and how the transformation initially proceeds. Understanding this process in humans may help explain how adorable children become surly teenagers.

3 Jun 2005

Genetics may play a role in the effectiveness of chemotherapy drugs

Today, the most common childhood cancer is cured in about 80 percent of patients; only forty years ago, this number was closer to five percent. In efforts to further increase the survival rate, researchers from St. Jude Children's Research Hospital, the University of Tennessee, and the University of Chicago studied how an individual's genetics might play a role in the effectiveness of chemotherapy drugs.

3 Jun 2005

Research shows how a virus uses the gene silencing machinery for its own infectious purposes

In the latest version of the hide-and-seek game between pathogens and the hosts they infect, researchers have found that a virus appears to cloak itself with a recently discovered gene silencing device to evade detection and destruction by immune cells.

3 Jun 2005

Genes News and Research

Researchers discover how hepatic-C virus evades immune system in acute and chronic infections

Experimental drug works best in combination with older remedy for Alzheimer's disease and other dementias

Accumulation of genetic changes is not solely determined by natural selection

Study of glial cells in the roundworm C. elegans may provide insight into a variety of human brain diseases

MicroRNAs play an important role in human cancer

New study shows tiny RNAs intimately associated with cancer

Researchers link aberrant 'microRNA' expression to human cancer

New understanding of microRNAs

Study is the first to identify involvement of chromosome 21 in developmental regression autism

New bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity

Girls who can't orgasm can blame it on their genes

Diversity of HLA genotypes in humans is shaped to a significant degree by pathogens

Gene therapy for arthritis is both feasible and safe

Statisticians learn how to analyze huge quantities of genetic data

Major advances in the global fight against eye disease

Intelligence and genetic disease link

Toxic chemicals that poisoned your great-grandparents may also damage your health

Gene research may help explain how adorable children become surly teenagers

Genetics may play a role in the effectiveness of chemotherapy drugs

Research shows how a virus uses the gene silencing machinery for its own infectious purposes

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