Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Astellas, Potenza collaborate to develop immuno-oncology therapeutics for patients with certain cancers

Astellas, Potenza collaborate to develop immuno-oncology therapeutics for patients with certain cancers

Cantrixil drug granted FDA Orphan Drug Designation for treatment of ovarian cancer

Cantrixil drug granted FDA Orphan Drug Designation for treatment of ovarian cancer

New mathematical model to predict pharmacodynamic activity may help improve drug discovery

New mathematical model to predict pharmacodynamic activity may help improve drug discovery

CiRA, Takeda collaborate to develop clinical applications of iPS cells

CiRA, Takeda collaborate to develop clinical applications of iPS cells

Optibrium to integrate ChemAxon's Plexus with StarDrop software platform

Optibrium to integrate ChemAxon's Plexus with StarDrop software platform

Clyde Biosciences, a leading drug toxicity testing company, closes Series A investment

Clyde Biosciences, a leading drug toxicity testing company, closes Series A investment

New pre-validated fluorinated fragment library boosts drug screening efficiency

New pre-validated fluorinated fragment library boosts drug screening efficiency

JPK reports on the use of the NanoWizard® 3 AFM system at the Hebrew University of Jerusalem

JPK reports on the use of the NanoWizard® 3 AFM system at the Hebrew University of Jerusalem

Scientists identify chemical compounds that block cancer-causing oncoprotein

Scientists identify chemical compounds that block cancer-causing oncoprotein

UQDI reveals that Anisina drug can kill melanoma cells

UQDI reveals that Anisina drug can kill melanoma cells

Vanderbilt researchers join multi-center effort to accelerate development of potential Ebola therapy

Vanderbilt researchers join multi-center effort to accelerate development of potential Ebola therapy

Sanford-Burnham, Daiichi Sankyo sign licensing agreement to expand development of small molecule

Sanford-Burnham, Daiichi Sankyo sign licensing agreement to expand development of small molecule

Aptuit increases API capacity to meet increased demand for integrated candidate-to-IND solutions

Aptuit increases API capacity to meet increased demand for integrated candidate-to-IND solutions

Novogen appoints PCG Advisory to manage investor-awareness program in the US

Novogen appoints PCG Advisory to manage investor-awareness program in the US

Novel molecule inhibits cancer-causing transcription factors

Novel molecule inhibits cancer-causing transcription factors

Selvita commences IND-enabling studies for its first oncology drug candidate

Selvita commences IND-enabling studies for its first oncology drug candidate

Aeterna Zentaris inks Material Transfer Agreement with MUSC

Aeterna Zentaris inks Material Transfer Agreement with MUSC

Broad Institute expands collaboration with Bayer to develop new cardiovascular therapies

Broad Institute expands collaboration with Bayer to develop new cardiovascular therapies

Cantrixil proves highly effective at killing human ovarian stem cells in pre-clinical study

Cantrixil proves highly effective at killing human ovarian stem cells in pre-clinical study

Fujifilm enters into definitive agreement to acquire Cellular Dynamics International

Fujifilm enters into definitive agreement to acquire Cellular Dynamics International

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