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Researchers identify mechanism with which cancer cells protect themselves against damage

Although many cancer drugs have already been in use for decades, their mode of action is still unknown. The new research results now challenge a mechanism of action that was previously proposed for a group of drugs and supported with experiments: the Topoisomerase I-inhibitor Camptothecin (Top1 inhibitor for short) and its derivatives used in chemotherapy, Topotecan and Irinotecan.

5 Mar 2012

Immediate Clinic acquires Doctors Express

The Ensign Group, Inc., the parent company of the Ensign group of skilled nursing, rehabilitative care services, hospice care, assisted living and urgent care companies, today announced that its urgent care joint venture, Immediate Clinic LLC, has acquired Doctors Express, a national urgent care franchise system.

5 Mar 2012

Novel partnership could transform breast cancer diagnosis

An innovative University of Sydney research partnership with private enterprise could see a radical change in how breast cancer is diagnosed, with the possibility to improve detection rates.

4 Mar 2012

Contraception coverage flap becoming key issue in Senate races

Congress can't seem to stop its debate on birth control -- and one reason is that it's bringing in lots of votes and money. ... Republicans are also using the issue to raise money among conservatives and broaden GOP support among Catholics, who are strongly opposed to Obama's contraceptive mandate. But, in general, the flap over birth control is helping Democrats solidify their base and gives them an opening to appeal to independent women, said Jennifer Duffy of the Cook Political Report.

3 Mar 2012

Promising results from initial trial of new ultrasonic breast cancer screening

Scientists have successfully completed an initial trial of a new, potentially more reliable, technique for screening breast cancer using ultrasound. The team at the National Physical Laboratory (NPL), the UK's National Measurement Institute, working with the University Hospitals Bristol NHS Foundation Trust, are now looking to develop the technique into a clinical device.

3 Mar 2012

Critical new details about structure of enterovirus 71

Researchers have discovered critical new details about the structure of a virus that causes potentially fatal brain swelling and paralysis in children, pointing toward designs for antiviral drugs to treat the disease.

3 Mar 2012

Scientists determine chemical features of DHPS enzyme's active site

More than 70 years after the first sulfa drugs helped to revolutionize medical care and save millions of lives, St. Jude Children's Research Hospital scientists have determined at an atomic level the mechanism these medications use to kill bacteria. The discovery provides the basis for a new generation of antibiotics that would likely be harder for bacteria to resist and cause fewer side effects.

2 Mar 2012

Bisphosphonates improve fixation of dental impants in human bones

Millions of people have bad teeth replaced with implants. Often following the procedure, they are unable to chew food for up to six months, until the implant has become fixated in the bone. Now, for the first time, a drug coating that has been tested on humans allows titanium screws to adhere to the bone better and faster. The Link-ping researchers behind the method report that the results are good.

2 Mar 2012

$DXA scan should be done at shorter intervals for women at high risk for fracture$

DXA scan should be done at shorter intervals for women at high risk for fracture

Although a recent study suggests that women with normal results on dual-energy X-ray absorptiometry (DXA) scans at ages 67 and older may wait up to 15 years for a second test, a Viewpoint article published today in the Journal of Bone and Mineral Research (JBMR) cautions that such a lengthy interval is inappropriate for many adults.

2 Mar 2012

Mayo researchers gain insights into function of histone chaperones

Mayo Clinic researchers have gained insights into the function of a member of a family of specialized proteins called histone chaperones. Using nuclear magnetic resonance (NMR) spectroscopy and X-ray crystallography, they have determined the 3-D structure and interactions of the histone chaperone Rtt106 down to the atomic details.

1 Mar 2012

New Fort Collins and Loveland medical offices for Kaiser Permanente Colorado

Kaiser Permanente Colorado, the state's largest non-profit health plan, has announced the locations of its new medical office buildings opening this fall in Fort Collins and Loveland.

23 Feb 2012

Radiation risk from Japan's nuclear disaster debris not a worry, but other aspects might be

The first anniversary is approaching of the March, 2011, earthquake and tsunami that devastated Fukushima, Japan, and later this year debris from that event should begin to wash up on U.S. shores - and one question many have asked is whether that will pose a radiation risk.

23 Feb 2012

Questcor fourth quarter net sales increase to $75.5 million

Questcor Pharmaceuticals, Inc. today reported financial results for the fourth quarter and full year ended December 31, 2011.

22 Feb 2012

Academic and industry leaders team up to develop next generation medical imaging technology

For over a decade, GE Healthcare has partnered with academic researchers from Purdue, Notre Dame and Michigan, and experts from Intel, to develop Veo – the world’s first Model-Based Iterative Reconstruction (MBiR) technique. Available on GE’s Discovery CT750 HD, Veo changes the rules of CT imaging by helping physicians provide accurate diagnoses with high quality images while enabling them to lower patients’ radiation dose levels.

22 Feb 2012

First ever publication with data on head impacts from youth football players

The Virginia Tech - Wake Forest University School of Biomedical Engineering and Sciences (SBES) announces the first ever publication with data on head impacts from youth football players. The paper is published in the Annals of Biomedical Engineering and is available online for free download. The manuscript includes the details of over 700 head impacts measured on 7 and 8 year old youth football players.

22 Feb 2012

New analysis highlights ongoing scale of tobacco problem among children

Every year around 157,000 children aged 11-15 start smoking - that's enough to fill 5,200 classrooms or make up nearly 14,000 junior football teams. These shocking figures, revealed in a new analysis by Cancer Research UK, highlight the ongoing scale of the tobacco problem, and underline the importance of sustained action to discourage young people from starting to smoke, including by introducing plain packaging for all tobacco products as soon as possible.

22 Feb 2012

State roundup: Calif. expands uninsured access, gives adult day care reprieve

Nearly two years before the federal health reform law kicks in, 10 California counties have expanded medical coverage to more than 250,000 people who were previously uninsured, according to new state data.

22 Feb 2012

GTx fourth quarter net loss increases to $10.7 million

GTx, Inc. today provided a Company update and reported financial results for the fourth quarter and full year 2011.

21 Feb 2012

Biochemists determine first crystal structure of an immunoproteasome

Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively kills cells that due to a viral infection present non-self peptides at their surface. In autoimmune diseases this mechanism is deregulated and the immune system also eliminates uninfected cells by mistake.

16 Feb 2012

Injury Prevention in Active Youth

Over the past few decades there has been an increase in injury to youth participating in sport. The issue of youth sport injury has become a conundrum because if there is an increase in injury, then subsequently there is usually an increase in participation. With the insurgence of childhood obesity, youth participation in sporting activities has been encouraged.It has been proven that regularly scheduled physical activity is associated with health improvements and reduced incidence of disease.

16 Feb 2012