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Scientists reveal role of lung scavenger cells in liver cancer spread to the lungs

Hepatocellular carcinoma is the most common form of liver cancer, and the third biggest cause of death from cancer worldwide.

4 Jun 2018

Researchers identify racial differences in breast cancer immune microenvironment

Roswell Park Comprehensive Cancer Center researchers have identified significant differences in the immune microenvironment of breast cancer tumors between African-American and white women, shedding light on the ways in which race can influence cancer development and outcomes.

4 Jun 2018

Detailed structure of protein pair offers blueprint for new medicines

Walter and Eliza Hall Institute researchers have visualized for the first time how the protein SOCS1 'switches off' cell signaling to dampen immune responses and block cancer growth.

4 Jun 2018

Novel programmed shape-morphing scaffolds developed to facilitate facile 3D endothelialization

Recently, a research team led by Dr. DU Xuemin at the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences created a new shape-morphing scaffold, enabling programmed deformation from a 2D planar cell-laden structure to a well-defined 3D tubular shape, which facilitated the facile 3D endothelialization of small-diameter vascular grafts.

4 Jun 2018

Free-floating DNA analysis test may help detect early-stage lung cancer

A test that analyzes free-floating DNA in the blood may be able to detect early-stage lung cancer, a preliminary report from the ongoing Circulating Cell-Free Genome Atlas study suggests.

4 Jun 2018

Researchers develop novel microscopy to observe cellular focal adhesion dynamics

Focal adhesions are large specialized proteins that are located in the area where a cell membrane meets the extracellular matrix, a collection of molecules surrounding the cells that provide support and regulate micromechanical signals to the cells.

4 Jun 2018

Phase I trial shows safety of investigational drug in treating chronic lymphocytic leukemia

Reporting results from a first-in-human phase I clinical trial, researchers at University of California San Diego School of Medicine have found that treatment with cirmtuzumab, an experimental monoclonal antibody-based drug, measurably inhibited the "stemness" of chronic leukemia cancer cells - their ability to self-renew and resist terminal differentiation and senescence.

1 Jun 2018

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Bristol-Myers Squibb Company today announced patient-reported outcomes data from the Phase 3 CheckMate -214 trial in intermediate- and poor-risk patients with advanced renal cell carcinoma treated with the Immuno-Oncology combination Opdivo plus low-dose Yervoy versus sunitinib over a two-year follow-up period.

1 Jun 2018

MD Anderson and Amgen collaborate to accelerate early-stage oncology therapies

The University of Texas MD Anderson Cancer Center and Amgen today announced two multi-year collaboration agreements aimed at accelerating development of a variety of Amgen's early-stage oncology therapies for patients with leukemia, myelodysplastic syndromes, multiple myeloma, small-cell lung cancer, and other non-lung cancers with small-cell histologies.

1 Jun 2018

International respiratory group calls for immediate ban on flavorings and marketing of e-cigarettes

In a statement published in the European Respiratory Journal, a coalition of respiratory doctors and scientists from six continents have warned of the dangers posed to children and adolescents by electronic cigarettes.

1 Jun 2018

Discovering Antibodies with Universal Specificity

Professor Hedda Wardemann discusses our current knowledge of antibody specificity and how her research team are challenging this, through the discovery of anti-bacterial antibodies with universal specificity.

1 Jun 2018

Rockefeller scientists shed new light on the neuroscience of sleep

A good night of sleep entails about eight hours of blissful immobility--a state of near paralysis that, though welcome at night, would be inconvenient during the day. In a recent paper published in Cell Reports, Rockefeller scientists shed new light on the transitions between a wakeful, active state and the stillness of sleep.

1 Jun 2018

Scientists identify three new distinct breast epithelial cell populations

Researchers from the University of California, Irvine School of Medicine, in collaboration with scientists at UCSF and Northwestern University, have profiled human breast epithelial cells, identifying three new distinct epithelial cell populations.

1 Jun 2018

Salk researchers discover molecule that destroys key HIV protein

One of the many challenges in treating HIV is that the virus can lie dormant in cells, quietly evading immune detection until it suddenly roars to life without warning and begins replicating furiously.

1 Jun 2018

Researchers reveal role NAD+ molecule in turning on genes that make fat cells

Glucose is the energy that fuels cells, and the body likes to store glucose for later use. But too much glucose can contribute to obesity, and scientists have long wanted to understand what happens within a cell to tip the balance.

1 Jun 2018

Scientists report involvement of estrogen hormone receptor in autoimmune diseases

Women are more prone to the development of autoimmune diseases. The female hormone estrogen is likely to affect the immune system.

1 Jun 2018

Researchers discover three genes that may have contributed to evolution of large human brain

Three genes involved in nerve cell generation in the brain emerged roughly 3.5 million years ago and may have contributed to the rapid evolution of the large human brain, Howard Hughes Medical Institute (HHMI) Investigator David Haussler and colleagues report on May 31, 2018, in the journal Cell.

1 Jun 2018

Cancer cells can use lipid molecules as fuel for growth, shows study

Cancer cells can when the blood supply is low use lipid molecules as fuel instead of blood glucose. This has been shown in animal tumor models by researchers at Karolinska Institutet in Sweden in a study published in Cell Metabolism.

1 Jun 2018

Hunger peptides sent through the brain's fluid cause appetite, shows study

A USC study shows the brain's plumbing system serves double duty, flushing waste and channeling a hunger molecule that tells you when you should eat.

1 Jun 2018

Study could open up new treatment approaches for neurodegenerative diseases

Cell biologists have deepened understanding of proteins associated with neurodegenerative diseases. The findings could open up new treatment approaches for disorders including Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis (ALS), among others.

31 May 2018

B Cell News and Research

Scientists reveal role of lung scavenger cells in liver cancer spread to the lungs

Researchers identify racial differences in breast cancer immune microenvironment

Detailed structure of protein pair offers blueprint for new medicines

Novel programmed shape-morphing scaffolds developed to facilitate facile 3D endothelialization

Free-floating DNA analysis test may help detect early-stage lung cancer

Researchers develop novel microscopy to observe cellular focal adhesion dynamics

Phase I trial shows safety of investigational drug in treating chronic lymphocytic leukemia

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

MD Anderson and Amgen collaborate to accelerate early-stage oncology therapies

International respiratory group calls for immediate ban on flavorings and marketing of e-cigarettes

Discovering Antibodies with Universal Specificity

Rockefeller scientists shed new light on the neuroscience of sleep

Scientists identify three new distinct breast epithelial cell populations

Salk researchers discover molecule that destroys key HIV protein

Researchers reveal role NAD+ molecule in turning on genes that make fat cells

Scientists report involvement of estrogen hormone receptor in autoimmune diseases

Researchers discover three genes that may have contributed to evolution of large human brain

Cancer cells can use lipid molecules as fuel for growth, shows study

Hunger peptides sent through the brain's fluid cause appetite, shows study

Study could open up new treatment approaches for neurodegenerative diseases

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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