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Prolonged exposure therapy shows greater benefit adolescent girls with sexually abused PTSD

Adolescents girls with sexual abuse-related posttraumatic stress disorder (PTSD) experienced greater benefit from prolonged exposure therapy (a type of therapy that has been shown effectiveness for adults) than from supportive counseling, according to a study appearing in the December 25 issue of JAMA.

26 Dec 2013

CAC screening plays more prominent role in determining risk for heart attack and stroke

A new study shows that coronary artery calcium (CAC) screening, an assessment tool that is not currently recommended for people considered at low risk, should play a more prominent role in helping determine a person’s risk for heart attack and heart disease-related death, as well as the need for angioplasty or bypass surgery.

26 Dec 2013

Researchers complete genomic analysis of cervical cancer in two patient populations

Researchers from the Boston area, Mexico, and Norway have completed a comprehensive genomic analysis of cervical cancer in two patient populations. The study identified recurrent genetic mutations not previously found in cervical cancer, including at least one for which targeted treatments have been approved for other forms of cancer.

25 Dec 2013

Madison Dearborn Partners signs definitive agreement to acquire Ikaria

Madison Dearborn Partners announced today that it has signed a definitive agreement under which it will acquire a majority ownership position in Ikaria, Inc., a leading provider of proprietary and innovative therapies for the critical care units in hospitals.

25 Dec 2013

Cognitive behavioral therapy reduces headache frequency, migraine-related disability in children

Among children and adolescents with chronic migraine, the use of cognitive behavioral therapy resulted in greater reductions in headache frequency and migraine-related disability compared with headache education, according to a study appearing in the December 25 issue of JAMA.

25 Dec 2013

Prolonged exposure therapy shows greater success for treating adolescent PTSD patients

Researchers at Penn Medicine report in the December 25 issue of JAMA that a modified form of prolonged exposure therapy - in which patients revisit and recount aloud their trauma-related thoughts, feelings and situations - shows greater success than supportive counseling for treating adolescent PTSD patients who have been sexually abused.

25 Dec 2013

Cell transplantation, gene therapy combination to open new therapeutic avenues for Alzheimer's disease

In a recent study published in the Neural Regeneration Research (Vol. 8, No. 33, 2013), Prof. Feng Li and team from Zhongshan School of Medicine, Sun Yat-sen University in China, synthesized a 19-nt oligonucleotide targeting BACE1, the key enzyme in amyloid beta protein (Aβ) production, and introduced it into the pSilenCircle vector to construct a short hairpin (shRNA) expression plasmid against the BACE1 gene.

24 Dec 2013

Concordia Healthcare acquires Pinnacle Biologics

Concordia Healthcare Corp., an integrated, specialty healthcare company focused on the acquisition of legacy pharmaceutical products and medical devices and the acquisition and/or development of orphan drugs, announced today that it has acquired Pinnacle Biologics, Inc., a U.S.-based biopharmaceutical company specializing in legacy pharmaceuticals which have the potential for development as orphan drugs to treat cancer indications in addition to those for which they have previously been approved.

24 Dec 2013

Healthcare workers' hands contaminated with C. difficile after routine care, study shows

A new study finds nearly one in four healthcare workers' hands were contaminated with Clostridium difficile spores after routine care of patients infected with the bacteria. The study was published in the January issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

24 Dec 2013

Treating depression fails to reverse cognitive deficits in bipolar disorder

Successful treatment of depression with total sleep deprivation does not improve neuropsychologic deficits in bipolar patients, despite improving clinical symptoms, Italian researchers report.

24 Dec 2013

Transplanting self-donated Schwann cells aids hind limb functional recovery

A study carried out at the University of Miami Miller School of Medicine for "The Miami Project to Cure Paralysis" has found that transplanting self-donated Schwann cells (SCs, the principal ensheathing cells of the nervous system) that are elongated so as to bridge scar tissue in the injured spinal cord, aids hind limb functional recovery in rats modeled with spinal cord injury.

24 Dec 2013

Researchers identify potential therapy for meibomian gland dysfunction

Meibomian gland dysfunction is the leading cause of dry eye disease, which affects tens of millions of Americans. However, there is no FDA-approved treatment for MGD. Researchers from the Schepens Eye Research Institute/Massachusetts Eye and Ear and Harvard Medical School have just identified a potential therapy.

24 Dec 2013

Researchers report new gene delivery method that targets tumor blood vessels

Working in mice, researchers at Washington University School of Medicine in St. Louis report developing a gene delivery method long sought in the field of gene therapy: a deactivated virus carrying a gene of interest that can be injected into the bloodstream and make its way to the right cells.

24 Dec 2013

Research review examines effectiveness of treatments for chronic skin wounds

A systematic review of 66 research papers focused on the treatment of skin ulcers suggests that most are so technically flawed that their results are unreliable. And even of those that pass muster, there is only weak evidence that some treatments work better than standard compression therapy or special stockings.

24 Dec 2013

Preoperative antibiotics within two hours of cardiac surgery decrease risk of developing SSIs

A new study found preoperative antibiotic therapy administered within two hours of cardiac surgery decreased the risk of developing surgical site infections (SSIs) significantly. The study was published in the January issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

23 Dec 2013

Reflux disease diagnosis: an interview with Professor Peter Dettmar, Managing Director of RD Biomed Limited

Generally speaking, reflux has been a major chronic issue for probably the last 40 or 50 years. When you look at the global population, depending on which country we're talking about, around 20% to 40% of individuals have reflux disease within their populations.

23 Dec 2013

European Commission approves update of Erbitux to treat patients with RAS wild-type mCRC

Merck Serono, the biopharmaceutical division of Merck, today announced that the European Commission has approved the Type II variation to amend the Erbitux(cetuximab) product information, updating the indication for Erbitux to the treatment of patients with RAS wild-type metastatic colorectal cancer (mCRC).

23 Dec 2013

Study shows CAC screening plays prominent role in determining person's risk for heart attack and stoke

A new study shows that coronary artery calcium (CAC) screening, an assessment tool that is not currently recommended for people considered at low risk, should play a more prominent role in helping determine a person's risk for heart attack and heart disease-related death, as well as the need for angioplasty or bypass surgery.

23 Dec 2013

Finding suggests new route for packaging RNA molecules of interest into nanovesicles

The role of microRNAs is fundamental for the correct moment-to-moment adjustment in the expression of target genes. "Before this study, we already knew that these small molecules could be packaged into small vesicles and exported to the extracellular space, to be later captured by other cells and in this way play an important role in intercellular communication," explains CNIC researcher Carolina Villarroya, the first author on the study.

23 Dec 2013

RaySearch receives 2 orders for RayStation treatment planning system from proton treatment centers

RaySearch Laboratories AB has received two orders for its RayStation® treatment planning system from the proton treatment centers Seattle ProCure Management LLC in Seattle, Washington, and Princeton ProCure Management LLC in Princeton, New Jersey. The two centers will use RayStation® for treatment planning of proton radiation therapy.

23 Dec 2013

Therapy News and Research

Prolonged exposure therapy shows greater benefit adolescent girls with sexually abused PTSD

CAC screening plays more prominent role in determining risk for heart attack and stroke

Researchers complete genomic analysis of cervical cancer in two patient populations

Madison Dearborn Partners signs definitive agreement to acquire Ikaria

Cognitive behavioral therapy reduces headache frequency, migraine-related disability in children

Prolonged exposure therapy shows greater success for treating adolescent PTSD patients

Cell transplantation, gene therapy combination to open new therapeutic avenues for Alzheimer's disease

Concordia Healthcare acquires Pinnacle Biologics

Healthcare workers' hands contaminated with C. difficile after routine care, study shows

Treating depression fails to reverse cognitive deficits in bipolar disorder

Transplanting self-donated Schwann cells aids hind limb functional recovery

Researchers identify potential therapy for meibomian gland dysfunction

Researchers report new gene delivery method that targets tumor blood vessels

Research review examines effectiveness of treatments for chronic skin wounds

Preoperative antibiotics within two hours of cardiac surgery decrease risk of developing SSIs

Reflux disease diagnosis: an interview with Professor Peter Dettmar, Managing Director of RD Biomed Limited

European Commission approves update of Erbitux to treat patients with RAS wild-type mCRC

Study shows CAC screening plays prominent role in determining person's risk for heart attack and stoke

Finding suggests new route for packaging RNA molecules of interest into nanovesicles

RaySearch receives 2 orders for RayStation treatment planning system from proton treatment centers

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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