Therapy News and Research

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How do people become depressed? An interview with Anna Watters and Professor Lea Williams, University of Sydney

A clinical diagnosis of depression (i.e. major depressive disorder) is currently defined on the basis of reported symptoms.

19 Feb 2014

Ticks infected with the bacterium that causes Lyme disease widespread in San Francisco Bay Area

As winter turns to spring and many Northern Californians plan outdoor adventures, a mysterious, potentially debilitating threat looms.

19 Feb 2014

Study shows one-quarter of high risk patients do not receive anticoagulants after ablation of AF

One-quarter of high risk patients do not receive anticoagulants after ablation of atrial fibrillation (AF), according to the latest survey of European practice.

19 Feb 2014

FDA approves CSC’s Phase II clinical trial for cancer immunotherapy in women with ovarian cancer

California Stem Cell, Inc. (CSC) announced today that the U.S. Food and Drug Administration (FDA) has approved the Company's application to begin a Phase II clinical trial exploring the potential of a patient-specific cancer immunotherapy in women with Stage III or IV ovarian, fallopian tube or primary peritoneal cancer.

19 Feb 2014

Study examines brain activity of alcohol-dependent women

A new Indiana University study that examines the brain activity of alcohol-dependent women compared to women who were not addicted found stark and surprising differences, leading to intriguing questions about brain network functions of addicted women as they make risky decisions about when and what to drink.

19 Feb 2014

Duke researchers getting closer to generate replacement cartilage

By combining a synthetic scaffolding material with gene delivery techniques, researchers at Duke University are getting closer to being able to generate replacement cartilage where it's needed in the body.

19 Feb 2014

Majority of women who undergo mastectomy go on to get breast reconstruction

A new study finds that the majority of women who undergo mastectomy for breast cancer go on to get breast reconstruction, a practice that has increased dramatically over time.

19 Feb 2014

CytoDyn submits PRO 140 Phase 2b trial protocol to FDA for treatment substitution in HIV patients

CytoDyn Inc., a biotechnology company focused on the development of new therapies for combating infection with immune deficiency viruses, announced today that the Company has submitted a Phase 2b clinical trial protocol, for its lead product candidate, PRO 140, to the U.S. Food and Drug Administration for treatment substitution in patients with Human Immunodeficiency Virus (HIV).

19 Feb 2014

Scientists develop mathematical method for classifying forms of glioblastoma

Scientists at The Wistar Institute have developed a mathematical method for classifying forms of glioblastoma, an aggressive and deadly type of brain cancer, through variations in the way these tumor cells "read" genes. Their system was capable of predicting the subclasses of glioblastoma tumors with 92 percent accuracy. With further testing, this system could enable physicians to accurately predict which forms of therapy would benefit their patients the most.

18 Feb 2014

Viamet announces positive interim results from VT-1161 Phase 2 study in patients with AVVC

Viamet Pharmaceuticals Inc. today reported positive interim results from an ongoing Phase 2 study of VT-1161, the Company's novel oral antifungal compound, in patients with moderate to severe acute vulvovaginal candidiasis (AVVC). This study is intended as a precursor to a Phase 2b study in patients with recurrent vulvovaginal candidiasis (RVVC).

18 Feb 2014

FDA grants accelerated approval to NORTHERA (droxidopa) for patients with symptomatic NOH

Chelsea Therapeutics International, Ltd. today announced that the U.S. Food and Drug Administration granted accelerated approval of NORTHERA (droxidopa) for the treatment of symptomatic neurogenic orthostatic hypotension (NOH). NORTHERA is the first and only therapy approved by the FDA which demonstrates symptomatic benefit in patients with NOH.

18 Feb 2014

Study shows how immune system reconstitutes itself following immune-depleting therapy

A new study describes the complexity of the new T cell repertoire following immune-depleting therapy to treat multiple sclerosis, improving our understanding of immune tolerance and clinical outcomes.

18 Feb 2014

New therapeutic target may help repair muscle damage

Researchers at the Stanford University School of Medicine have pinpointed why normal aging is accompanied by a diminished ability to regain strength and mobility after muscle injury: Over time, stem cells within muscle tissues dedicated to repairing damage become less able to generate new muscle fibers and struggle to self-renew.

18 Feb 2014

Study reveals overall success rate of AF ablation in Europe

One-quarter of high risk patients do not receive anticoagulants after ablation of atrial fibrillation (AF), according to the latest survey of European practice.

18 Feb 2014

Researchers detail how psoralen blocks signaling pathway of HER2-positive cancers

A common compound known to fight lymphoma and skin conditions actually has a second method of action that makes it particularly deadly against certain aggressive breast tumors, researchers at Duke Medicine report.

18 Feb 2014

Valproic acid metabolism and obesity: an interview with Dr. Namandjé Bumpus, Johns Hopkins Medicine

Valproic acid is one of the most widely prescribed drugs for the treatment of epilepsy. It has also been shown to be effective for the treatment of mood disorders and migraine headaches.

17 Feb 2014

Advanced Accelerator Applications successfully completes capital increase of €41 million

Advanced Accelerator Applications, a fast growing international specialist in Molecular Nuclear Medicine (MNM), announced today that it had successfully completed a capital increase of €41 million.

17 Feb 2014

Researchers identify new type of regulatory blood cells that can combat brain inflammation

Hyperactivity of our immune system can cause a state of chronic inflammation. If chronic, the inflammation will affect our body and result in disease. In the devastating disease multiple sclerosis, hyperactivity of immune cells called T-cells induce chronic inflammation and degeneration of the brain. Researchers at BRIC, the University of Copenhagen, have identified a new type of regulatory blood cells that can combat such hyperactive T-cells in blood from patients with multiple sclerosis. By stimulating the regulatory blood cells, the researchers significantly decreased the level of brain inflammation and disease in a biological model.

17 Feb 2014

Study shows vitamin D may provide some relief for patients with chronic hives

A study by researchers at the University of Nebraska Medical Center shows vitamin D as an add-on therapy could provide some relief for chronic hives, a condition with no cure and few treatment options.

17 Feb 2014

Scientists discover novel antibody-based therapy that targets progression of kidney fibrosis

Scientists from the University of Sheffield have developed a novel antibody-based therapy which targets the progression of life threating kidney fibrosis.

16 Feb 2014

Therapy News and Research

How do people become depressed? An interview with Anna Watters and Professor Lea Williams, University of Sydney

Ticks infected with the bacterium that causes Lyme disease widespread in San Francisco Bay Area

Study shows one-quarter of high risk patients do not receive anticoagulants after ablation of AF

FDA approves CSC’s Phase II clinical trial for cancer immunotherapy in women with ovarian cancer

Study examines brain activity of alcohol-dependent women

Duke researchers getting closer to generate replacement cartilage

Majority of women who undergo mastectomy go on to get breast reconstruction

CytoDyn submits PRO 140 Phase 2b trial protocol to FDA for treatment substitution in HIV patients

Scientists develop mathematical method for classifying forms of glioblastoma

Viamet announces positive interim results from VT-1161 Phase 2 study in patients with AVVC

FDA grants accelerated approval to NORTHERA (droxidopa) for patients with symptomatic NOH

Study shows how immune system reconstitutes itself following immune-depleting therapy

New therapeutic target may help repair muscle damage

Study reveals overall success rate of AF ablation in Europe

Researchers detail how psoralen blocks signaling pathway of HER2-positive cancers

Valproic acid metabolism and obesity: an interview with Dr. Namandjé Bumpus, Johns Hopkins Medicine

Advanced Accelerator Applications successfully completes capital increase of €41 million

Researchers identify new type of regulatory blood cells that can combat brain inflammation

Study shows vitamin D may provide some relief for patients with chronic hives

Scientists discover novel antibody-based therapy that targets progression of kidney fibrosis

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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