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Atrial fibrillation diagnosis associated with 45% increased risk of mild cognitive impairment

Atrial fibrillation (AF) diagnosis was associated with a 45% increased risk of mild cognitive impairment (MCI) among a cohort of 4.3 million individuals in the UK, according to a new study published in JACC: Advances.

25 Oct 2023

Global clinical trial provides new evidence on simvastatin and vitamin C for COVID-19

The Global Coalition for Adaptive Research (GCAR) in collaboration with the University of Pittsburgh and UPMC, on behalf of the REMAP-CAP Investigator Network, announce clinical trial results examining the use of vitamin C and simvastatin to treat severely ill patients with COVID-19.

25 Oct 2023

Brain-computer interface helps ALS patient control devices, navigate communication board

It's the day after the Baltimore Orioles clinched the American League East Championship with their 100th win of the season, and lifelong fan Tim Evans is showing his pride on his sleeve.

25 Oct 2023

Could the microbiome hold the key to diagnosing and treating biliary tract cancer?

A recent study in "Microorganisms" delves into the relationship between the microbiome and biliary tract cancer, revealing distinct microbial compositions in patients compared to healthy individuals. This research highlights potential diagnostic biomarkers and suggests that altering gut microbial composition might enhance responses to cancer immunotherapy.

24 Oct 2023

Blood test detects cancer earlier in individuals with Li-Fraumeni syndrome

Researchers from The Hospital for Sick Children (SickKids), the Ontario Institute for Cancer Research (OICR) and University Health Network (UHN) have demonstrated that by analyzing patients' blood samples, they are able to detect cancer earlier in individuals with Li-Fraumeni syndrome, an inherited condition with an almost 100 percent life-time risk of developing cancer.

24 Oct 2023

Biofilm probiotic effective in preventing necrotizing enterocolitis in piglet model

Necrotizing enterocolitis (NEC) is a debilitating and deadly condition that affects infants who were born preterm.

24 Oct 2023

HIF-2α inhibitor belzutifan significantly reduces progression of clear cell renal cell carcinoma

Belzutifan significantly reduced the risk of progression of clear cell renal cell carcinoma (ccRCC), the most common type of kidney cancer, in patients previously treated with immune checkpoint inhibitors and anti-angiogenic therapies compared with everolimus in a phase 3 clinical trial.

24 Oct 2023

Finding and targeting dormant tumor cells to prevent breast cancer recurrence

While breast cancer survival continues to improve, thanks to advances in detection and treatment, when breast cancer recurs – or returns after initial treatment – it is incurable.

24 Oct 2023

Neoadjuvant pembrolizumab achieves major pathologic response in more than half of patients with resectable melanoma

In exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major pathologic response in more than half of surgical specimens taken from patients who had been treated with neoadjuvant (pre-operative) pembrolizumab.

24 Oct 2023

Heated yoga sessions linked to greater reductions in depressive symptoms

In a randomized controlled clinical trial of adults with moderate-to-severe depression, those who participated in heated yoga sessions experienced significantly greater reductions in depressive symptoms compared with a control group.

24 Oct 2023

Resistant potato starch usage found to be feasible and safe for hematopoietic stem cell transplantation patients

The use of resistant potato starch (RPS), to modify gut microbial metabolism.

24 Oct 2023

Study shows TAVR as a good alternative to open-heart surgery in younger patients with aortic stenosis

Patients with a dysfunctional aortic heart valve who received a new, prosthetic valve through a minimally invasive procedure had similar outcomes at five years as those who underwent open-heart surgery, a new study shows.

24 Oct 2023

Quick genetic test offers hope for sick, undiagnosed kids. but few insurers offer to pay.

Just 48 hours after her birth in a Seattle-area hospital in 2021, Layla Babayev was undergoing surgery for a bowel obstruction.

23 Oct 2023

Million Hearts model cuts heart attack and stroke risk without hiking Medicare costs

The Million Hearts payment model, which incentivizes healthcare organizations to reduce cardiovascular risk among Medicare beneficiaries, led to a modest but significant reduction in new-onset myocardial infarctions and strokes over five years. The model did not result in a significant increase in Medicare spending, suggesting a cost-effective way to improve cardiovascular health.

23 Oct 2023

Chemotherapy plus immunotherapy improves survival in patients with metastatic urothelial cancer

A clinical trial co-led by Mount Sinai researchers is the first to show that using chemotherapy with immunotherapy resulted in improved survival in patients with an advanced type of bladder cancer.

22 Oct 2023

Short course of induction chemotherapy can reduce cervical cancer relapse and death by 35%

The INTERLACE phase III trial, funded by Cancer Research UK and UCL Cancer Trials Centre, assessed whether a short course of induction chemotherapy (IC) prior to chemoradiation (CRT) could reduce the rate of relapse and death among patients with locally advanced cervical cancer.

22 Oct 2023

Dual-action drug produces shows promising results in neuroendocrine tumor trial

A drug that simultaneously strikes cancer cells' growth circuits and pipeline to the bloodstream produced encouraging results in a clinical trial involving patients with advanced neuroendocrine tumors, according to a study led by Dana-Farber Cancer Institute investigators.

22 Oct 2023

Everolimus after surgery may benefit patients with very-high-risk clear cell renal cell carcinoma

A secondary analysis from the SWOG S0931 EVEREST trial has found that in the subgroup of patients with clear-cell renal cell carcinoma (RCC) who were at very-high risk of recurrence, those who were treated with everolimus after surgery had a statistically significant improvement in recurrence-free survival compared to patients getting placebo after surgery.

22 Oct 2023

Pupil size may predict response to TMS treatment for depression

New findings from researchers at UCLA Health suggest that measuring changes in how pupils react to light could help predict recovery from depression and personalize transcranial magnetic stimulation (TMS) treatment of major depressive disorder.

20 Oct 2023

Mediterranean diet and exercise: A powerful combo for transforming body composition

The Mediterranean diet coupled with physical activity may help achieve a clinically improved body composition

20 Oct 2023

Clinical Trial News and Research

Atrial fibrillation diagnosis associated with 45% increased risk of mild cognitive impairment

Global clinical trial provides new evidence on simvastatin and vitamin C for COVID-19

Brain-computer interface helps ALS patient control devices, navigate communication board

Could the microbiome hold the key to diagnosing and treating biliary tract cancer?

Blood test detects cancer earlier in individuals with Li-Fraumeni syndrome

Biofilm probiotic effective in preventing necrotizing enterocolitis in piglet model

HIF-2α inhibitor belzutifan significantly reduces progression of clear cell renal cell carcinoma

Finding and targeting dormant tumor cells to prevent breast cancer recurrence

Neoadjuvant pembrolizumab achieves major pathologic response in more than half of patients with resectable melanoma

Heated yoga sessions linked to greater reductions in depressive symptoms

Resistant potato starch usage found to be feasible and safe for hematopoietic stem cell transplantation patients

Study shows TAVR as a good alternative to open-heart surgery in younger patients with aortic stenosis

Quick genetic test offers hope for sick, undiagnosed kids. but few insurers offer to pay.

Million Hearts model cuts heart attack and stroke risk without hiking Medicare costs

Chemotherapy plus immunotherapy improves survival in patients with metastatic urothelial cancer

Short course of induction chemotherapy can reduce cervical cancer relapse and death by 35%

Dual-action drug produces shows promising results in neuroendocrine tumor trial

Everolimus after surgery may benefit patients with very-high-risk clear cell renal cell carcinoma

Pupil size may predict response to TMS treatment for depression

Mediterranean diet and exercise: A powerful combo for transforming body composition

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