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Posaconazole found to be effective as a small molecule fusion inhibitor against SARS-CoV-2 variants

Researchers evaluated the importance of the Ex3Lx6L motif in SARS-CoV-2 entry into host cells mediated by the spike protein syncytium formation and membrane fusion.

22 Mar 2022

Research characterizes efficacy of various COVID vaccines against Omicron BA.1 and BA.2

A recent study posted to the bioRxiv* preprint server demonstrated the neutralizing capacity of existing SARS-CoV-2 vaccines against the severe acute respiratory coronavirus 2 (SARS-CoV-2) Omicron BA.2 and BA.1 sublineages.

22 Mar 2022

Environmental surveillance for early detection of COVID-19 outbreaks

A recent study posted to the medRxiv* preprint server investigated whether environmental samples could serve as early indicators for detecting severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in large communities.

22 Mar 2022

Multiple inter-variant recombination events identified in Omicron subvariants

Newly emerging and circulating Omicron subvariants have originated partially through recombination with other variants.

20 Mar 2022

Cov2clusters: Novel method for producing stable genomic clusters of SARS-CoV-2 cases

Researchers present a novel method for producing stable genomic clustering of SARS-CoV-2 cases, Cov2clusters.

20 Mar 2022

Omicron BA.1.1 and BA.2 subvariants with new mutations in New Zealand and Hong Kong

A new study describes mutations found in the SARS-CoV-2 BA.1 variant in Hong Kong and New Zealand.

20 Mar 2022

Hypoxia-inducible factors and SARS-CoV-2 manifestations

Researchers assessed the role of hypoxia-inducible factors in SARS-CoV-2 infection, respiratory symptoms, and epithelial damage.

18 Mar 2022

Innate and adaptive immune responses to BNT162b2 vaccination in mice

Researchers analyzed the innate and adaptive responses to the mRNA-based BNT162b2 COVID-19 vaccine in mice.

18 Mar 2022

New 'Shared Commitments' set out priority actions across the UK to improve healthcare through genomics

The UK government, Welsh and Scottish Governments and Northern Ireland Assembly have today (Friday 18 march) agreed a series of commitments to improve outcomes for patients through better genomic testing and access to clinical trials.

18 Mar 2022

Why does the SARS-CoV-2 Omicron variant escape immunity?

Researchers reveal the underlying mechanism associated with the Omicron variant’s increased transmissibility and ability to evade immunity.

17 Mar 2022

Novel screening method detects new N501T SARS-CoV-2 variant

Researchers develop two SARS-CoV-2 Mutation Discrimination assays that have been designed to detect 501 and 484 mutations on the spike protein.

17 Mar 2022

RNA-chopping enzyme Dicer stabilizes mammalian chromosomes with the help of BRD4 activator

Cells use RNA as a versatile tool to regulate the activity of their genes. Small snippets of RNA can fine-tune how much protein is produced from various genes; some small RNAs can shut genes off altogether.

17 Mar 2022

Study reports thiopurines inhibit the replication of the betacoronaviruses HCoV-OC43 and SARS-CoV-2

Researchers demonstrated that the thiopurines block coronaviruses spike protein assembly and integration into progeny virions.

17 Mar 2022

Study finds co-infected individuals carrying two distinct lineages of SARS-CoV-2 in Argentina

Researchers used molecular surveillance to identify cases of co-infection with SARS-CoV-2 variants of concern Delta and Omicron reported in Argentina during December 2021 and January 2022.

17 Mar 2022

Study reports reduced disease severity in Syrian hamsters during re-infection with SARS-CoV-2 Delta variant

Researchers studied the immune responses in Syrian hamsters re-infected with SARS-CoV-2 Delta and B.1 variants three months after the primary infection.

17 Mar 2022

Mayo Clinic researchers report differences in genomic data quality among racial groups

Mayo Clinic researchers studied the differences in genomic data quality among racial groups in one of the largest and most widely used cancer research datasets, The Cancer Genome Atlas.

17 Mar 2022

Study suggests single nucleotide polymorphism in interferon receptor impacts COVID-19 outcomes

Researchers reported the association of a single nucleotide polymorphism rs9984273 in the interferon-alpha/beta receptor gene with outcomes of acute respiratory distress syndrome and COVID-19.

17 Mar 2022

Exploring the connection between SARS-CoV-2 infection and the human gut microbiome

A recent study assessed the relationship between the human microbiome and COVID-19.

17 Mar 2022

Brain-wide association studies need thousands of people to achieve higher reproducibility

As brain scans have become more detailed and informative in recent decades, neuroimaging has seemed to promise a way for doctors and scientists to "see" what's going wrong inside the brains of people with mental illnesses or neurological conditions.

16 Mar 2022

The effects of anti-SARS-CoV-2 monoclonal antibodies on pregnant and postpartum women

Researchers examine the safety and efficacy of mAbs in pregnant and postpartum women with COVID-19.

16 Mar 2022

Genomic News and Research

Posaconazole found to be effective as a small molecule fusion inhibitor against SARS-CoV-2 variants

Research characterizes efficacy of various COVID vaccines against Omicron BA.1 and BA.2

Environmental surveillance for early detection of COVID-19 outbreaks

Multiple inter-variant recombination events identified in Omicron subvariants

Cov2clusters: Novel method for producing stable genomic clusters of SARS-CoV-2 cases

Omicron BA.1.1 and BA.2 subvariants with new mutations in New Zealand and Hong Kong

Hypoxia-inducible factors and SARS-CoV-2 manifestations

Innate and adaptive immune responses to BNT162b2 vaccination in mice

New 'Shared Commitments' set out priority actions across the UK to improve healthcare through genomics

Why does the SARS-CoV-2 Omicron variant escape immunity?

Novel screening method detects new N501T SARS-CoV-2 variant

RNA-chopping enzyme Dicer stabilizes mammalian chromosomes with the help of BRD4 activator

Study reports thiopurines inhibit the replication of the betacoronaviruses HCoV-OC43 and SARS-CoV-2

Study finds co-infected individuals carrying two distinct lineages of SARS-CoV-2 in Argentina

Study reports reduced disease severity in Syrian hamsters during re-infection with SARS-CoV-2 Delta variant

Mayo Clinic researchers report differences in genomic data quality among racial groups

Study suggests single nucleotide polymorphism in interferon receptor impacts COVID-19 outcomes

Exploring the connection between SARS-CoV-2 infection and the human gut microbiome

Brain-wide association studies need thousands of people to achieve higher reproducibility

The effects of anti-SARS-CoV-2 monoclonal antibodies on pregnant and postpartum women

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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