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Study: Environmental pollutants affect male reproduction in many species, including humans

In the St. Lawrence River near Montreal's sewage discharge site, male spottail shiners show the effects of pollution with more than one third of the fish having oocytes in their testes.

10 May 2018

Researchers identify six genes that predispose carriers to develop medulloblastoma

Researchers have identified six genes that predispose carriers to develop the brain tumor medulloblastoma and have used the discovery to craft genetic counseling and screening guidelines. The study appears today in the journal The Lancet Oncology.

10 May 2018

FDA seeks order of permanent injunction to stop two stem cell clinics from marketing stem cell products

The U.S. Food and Drug Administration, in two complaints filed today in federal court, is seeking permanent injunctions to stop two stem cell clinics from marketing stem cell products without FDA approval and for significant deviations from current good manufacturing practice requirements.

10 May 2018

Study finds neuroinflammation in spinal cord, nerve roots of patients with chronic sciatica

A study by Massachusetts General Hospital investigators has found, for the first time in humans, that patients with chronic sciatica - back pain that shoots down the leg - have evidence of inflammation in key areas of the nervous system.

10 May 2018

New case study shows CAR T therapy as viable option for AML patients

Chimeric Antigen Receptor T-cell therapy, also known as CAR T therapy, was named the biggest research breakthrough of 2017 by the American Society of Clinical Oncology. The personal gene therapy utilizes a patient's own immune cells to fight cancer.

9 May 2018

Study: Stigmatizing language in medical records may play a role in how the patient is treated

A Johns Hopkins study found that physicians who use stigmatizing language in their patients' medical records may affect the care those patients get for years to come.

9 May 2018

International research collaboration aims to prevent heart arrhythmias with gene therapy

The most common and potentially lethal complication following a heart attack is the heart's inability to do one of its most basic jobs: beat at a normal rate.

9 May 2018

Scripps Research professor wins 2018 RSC Bioorganic Chemistry Award

Floyd Romesberg, PhD, professor at The Scripps Research Institute, has won the 2018 Royal Society of Chemistry Bioorganic Chemistry Award for his ground-breaking contributions to the expansion of the genetic alphabet.

9 May 2018

New research may help elucidate racial differences in prostate cancer

New research published in Molecular Oncology may help explain why African American men are at a higher risk of being diagnosed with prostate cancer and a higher risk of dying from the disease compared with European American men.

9 May 2018

£4 million project seeks to find new therapies for promoting tissue repair

Stem cell scientists are to join forces with doctors to investigate methods of promoting tissue repair in the liver, lungs and joints.

9 May 2018

Advances in Cell Lineage Analysis

Dr. Jan Phillip Junker discusses the applications of CRISPR-Cas9 in cell lineage analysis and the development of tomo-seq; a method to study the spatial organization of cells within whole organisms.

9 May 2018

Johns Hopkins researchers identify protein clumps in diseased hearts

Similar to how protein clumps build up in the brain in people with some neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, protein clumps appear to accumulate in the diseased hearts of mice and people with heart failure, according to a team led by Johns Hopkins University researchers.

9 May 2018

Changing metabolic states of intestinal bacteria have an effect on MAIT defense cells

A little-explored group of immune cells plays an important role in the regulation of intestinal bacteria.

9 May 2018

Disruption of the body's circadian rhythm linked to increased risk of breast cancer

For years, doctors have associated the BRCA1 and BRCA2 gene mutations with an increased risk of breast cancer.

9 May 2018

Tissue-engineered islets used to treat sudden-onset type 1 diabetes in mice

Researchers tissue-engineered human pancreatic islets in a laboratory that develop a circulatory system, secrete hormones like insulin and successfully treat sudden-onset type 1 diabetes in transplanted mice.

9 May 2018

Research findings could lead to new therapies to curb ovarian cancer metastasis

In order to spread their destruction, ovarian cancer cells must break free from their tumor home, travel through the fluid in the peritoneal cavity and attach to the outside of the abdominal organs--surfaces that are, by necessity, not sticky.

9 May 2018

Scientists develop computer algorithm that reveals gene networks activated in cancer cell

Recent headlines have cast suspicion on social network analysis, which can mine data from the internet to target advertisements or potentially influence elections.

9 May 2018

Potential stem cell treatment aids regeneration of heart muscle cells following heart attack

New research published in The Journal of Physiology has indicated a potential new stem cell treatment following a heart attack, by encouraging the regeneration of heart muscle cells. The low retention and survival rate of stem cells implanted in the heart had previously proven a sticking point for stem cell therapy following a heart attack.

9 May 2018

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

TRAIL, a member of the TNF family of ligands, causes caspase-dependent apoptosis through activation of its receptors, death receptor 4 and DR5.

9 May 2018

Findings confirm analytical principle that describes mutational processes and cancer development

When a cell develops into a tumor, something has gone terribly wrong: the uncontrolled growth, invasion of nearby tissues and finally metastasis are the result of many consecutive DNA mutations.

9 May 2018

B Cell News and Research

Study: Environmental pollutants affect male reproduction in many species, including humans

Researchers identify six genes that predispose carriers to develop medulloblastoma

FDA seeks order of permanent injunction to stop two stem cell clinics from marketing stem cell products

Study finds neuroinflammation in spinal cord, nerve roots of patients with chronic sciatica

New case study shows CAR T therapy as viable option for AML patients

Study: Stigmatizing language in medical records may play a role in how the patient is treated

International research collaboration aims to prevent heart arrhythmias with gene therapy

Scripps Research professor wins 2018 RSC Bioorganic Chemistry Award

New research may help elucidate racial differences in prostate cancer

£4 million project seeks to find new therapies for promoting tissue repair

Advances in Cell Lineage Analysis

Johns Hopkins researchers identify protein clumps in diseased hearts

Changing metabolic states of intestinal bacteria have an effect on MAIT defense cells

Disruption of the body's circadian rhythm linked to increased risk of breast cancer

Tissue-engineered islets used to treat sudden-onset type 1 diabetes in mice

Research findings could lead to new therapies to curb ovarian cancer metastasis

Scientists develop computer algorithm that reveals gene networks activated in cancer cell

Potential stem cell treatment aids regeneration of heart muscle cells following heart attack

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

Findings confirm analytical principle that describes mutational processes and cancer development

Immunology eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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