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Researchers show how unusual properties of A3G protein help fight HIV infection

A collaborative team led by a Northeastern University professor may have altered the way we look at drug development for HIV by uncovering some unusual properties of a human protein called APOBEC3G.

27 Nov 2013

Treatments based on behavioral or non-invasive physiological stimulation show greatest potential

Because the concept of permanent neurological injury has given way to recognition of the brain's potential for long-term regeneration ad reorganization, rehabilitations strategies are undergoing radical changes. The potential for five new translational interventions was examined in an article published ahead of print on November 13 by Neurology Clinical Practice: Barrett AM, Oh-Park M, Chen P, Ifejika NL: Five New Things in Neurorehabilitation.

27 Nov 2013

Restoring helpful bacteria of the gut and intestines may treat patients with RCDI, find scientists

Scientists at the Institute for Genome Sciences at the University of Maryland School of Medicine and physicians at Sinai Hospital, Baltimore, MD, have found that restoring the normal, helpful bacteria of the gut and intestines may treat patients suffering from recurrent Clostridium difficile infections. Transplanting fecal matter of healthy donors into patients with recurrent C. difficile infection appears to restore normal bacterial composition and resolve infection.

27 Nov 2013

Breakthrough discovery could lead to development of future therapeutics for prostate cancer

Drs. Andrew Goldstein, Owen Witte, and Tanya Stoyanova and their colleagues from UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have found that prostate cancer can develop in one type of stem cell, then evolve to be maintained by a stem cell that looks very different, making prostate cancer stem cells a "moving target" for treatments. The breakthrough discovery connects directly to the development of future therapeutics that target cancer and was published online ahead of print in the Proceedings of the National Academy of Sciences.

27 Nov 2013

Merck announces approval of NOXAFIL delayed-release tablets by FDA

Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved NOXAFIL® (posaconazole) 100 mg delayed-release tablets.

27 Nov 2013

EU-funded project develops new type of vaccine to tackle HIV virus infection

AIDS research has attempted many strategies to tackle the HIV virus infection. Now, a new type of vaccine developed within an EU-funded project, called EuroNeut-41, is based on one of the envelope proteins of the HIV virus, called the gp41 protein. What makes it interesting it that it is directly responsible for the fusion of the HIV virus into human cells. By integrating the gp41 protein into the vaccine, researchers try to trigger the production of antibodies that would block the entrance of HIV into human cells

27 Nov 2013

Research: Human neural stem cells could improve blood flow in critical limb ischemia

New research has shown human neural stem cells could improve blood flow in critical limb ischemia through the growth of new vessels. Critical limb ischemia is a disease that severely obstructs arteries and reduces the blood flow to legs and feet. CLI remains an unmet clinical problem and with an ageing population and the rise in type II diabetes, the incidence of CLI is expected to increase.

27 Nov 2013

Biochemist receives grant to identify pathway to regulate DNA damage repair in cancer cells

Chemotherapy and radiation therapy are often used to kill cancer cells by causing irreparable DNA damage. However, some cancer patients resist chemotherapy and radiation due to a highly active DNA damage repair system.

26 Nov 2013

Bruker receives FDA clearance to market MALDI Biotyper CA System in the U.S.

Bruker Corporation today announced that it has been granted U.S. FDA clearance under Section 510(k) to market its MALDI Biotyper CA System in the United States for the identification of Gram negative bacterial colonies cultured from human specimens.

26 Nov 2013

MSF launches film series to counterbalance rhetoric presenting the fight against HIV/AIDS as almost won

The fight against HIV/AIDS has been hailed as one of the most successful public health projects in human history, but teams from the international medical humanitarian organisation Médecins Sans Frontières/Doctors Without Borders (MSF) see the revolution as unfulfilled for millions of people excluded from treatment.

26 Nov 2013

SIMM and Crown Bioscience collaborate to build MCT center in China

Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences (CAS) and Crown Bioscience, Inc., announced today that they have reached an agreement to form a strategic collaboration focused on translational oncology and to join forces to build a mouse clinical trial (MCT) center at Crown Taicang campus, Taicang, Jiangsu province, China --SIMM-Crown Mouse Clinical Trial Center, or SCMC.

26 Nov 2013

HIV patients face higher risk of virologic failure than previously thought

People with human immunodeficiency virus (HIV) run a higher risk of virologic failure than previously thought, even when their number of RNA copies of the retrovirus per millilitre of blood is slightly above the detection threshold, according to a study by Claudie Laprise at the University of Montreal's Department of Social and Preventative Medicine.

26 Nov 2013

Researchers successfully target T lymphocytes which play key role in body's immune response

Researchers at the University of California, San Diego School of Medicine have successfully targeted T lymphocytes - which play a central role in the body's immune response - with another type of white blood cell engineered to synthesize and deliver bits of non-coding RNA or microRNA (miRNA).

26 Nov 2013

Viewpoints: Senate should reconsider treaty on protections for people with disabilities; HHS treading wrong way on payments for bone marrow donors

About a year ago the Senate fell five votes short of ratifying an international treaty that would improve protections for the disabled. It was an ignoble spectacle as the opponents rebuffed Bob Dole, a former colleague and disabled veteran, who came to the Senate floor to lobby for it.

26 Nov 2013

Alternative treatment for autism focuses on controlling the 'fight or flight' response

A novel approach to treating children diagnosed with autism spectrum disorder could help them navigate their world by teaching them to turn their symptoms into strengths.

26 Nov 2013

Researcher receives $225,000 grant to study epigenetic changes associated with chemotherapy

Western University cancer researcher Shun-Cheng (Shawn) Li, PhD, has been awarded a China-Canada Joint Health Research Initiative grant from the Canadian Institutes of Health Research (CIHR).

26 Nov 2013

Principal investigators at Nationwide Children's Hospital elected as AAAS Fellows

Brian K. Kaspar, PhD, and Veronica J. Vieland, PhD, principal investigators in The Research Institute at Nationwide Children's Hospital, have been named Fellows of the American Association for the Advancement of Science (AAAS).

26 Nov 2013

Occupational therapy can benefit children with autism

In one of the first randomized control trials studying an intervention for sensory problems in children with autism, researchers found that occupational therapy using the principles of sensory integration (OT-SI) provided better outcomes on parent-identified goals than standard care, according to results published November 10th in the Journal of Autism and Developmental Disorders.

26 Nov 2013

AATS, cardiovascular professional societies release overview of transcatheter therapies for mitral regurgitation

AATS and three cardiovascular professional societies today released an overview of transcatheter therapies for mitral regurgitation.

26 Nov 2013

Icahn School of Medicine receives $2.7M to investigate narrow pathway targeted immune therapy

The National Institutes of Health has awarded a research team at the Icahn School of Medicine at Mount Sinai $2.7 million to study systemic treatments for patients with moderate to severe atopic dermatitis (AD), also known as eczema.

26 Nov 2013

Therapy News and Research

Researchers show how unusual properties of A3G protein help fight HIV infection

Treatments based on behavioral or non-invasive physiological stimulation show greatest potential

Restoring helpful bacteria of the gut and intestines may treat patients with RCDI, find scientists

Breakthrough discovery could lead to development of future therapeutics for prostate cancer

Merck announces approval of NOXAFIL delayed-release tablets by FDA

EU-funded project develops new type of vaccine to tackle HIV virus infection

Research: Human neural stem cells could improve blood flow in critical limb ischemia

Biochemist receives grant to identify pathway to regulate DNA damage repair in cancer cells

Bruker receives FDA clearance to market MALDI Biotyper CA System in the U.S.

MSF launches film series to counterbalance rhetoric presenting the fight against HIV/AIDS as almost won

SIMM and Crown Bioscience collaborate to build MCT center in China

HIV patients face higher risk of virologic failure than previously thought

Researchers successfully target T lymphocytes which play key role in body's immune response

Viewpoints: Senate should reconsider treaty on protections for people with disabilities; HHS treading wrong way on payments for bone marrow donors

Alternative treatment for autism focuses on controlling the 'fight or flight' response

Researcher receives $225,000 grant to study epigenetic changes associated with chemotherapy

Principal investigators at Nationwide Children's Hospital elected as AAAS Fellows

Occupational therapy can benefit children with autism

AATS, cardiovascular professional societies release overview of transcatheter therapies for mitral regurgitation

Icahn School of Medicine receives $2.7M to investigate narrow pathway targeted immune therapy

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