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Scientists discover potential therapeutic target for devastating premature aging disease

Scientists from the University of Cambridge have identified a potential therapeutic target in the devastating genetic disease Hutchinson-Gilford Progeria Syndrome (HGPS), which is characterized by premature aging.

27 Apr 2018

Specific type of RNA editing plays key role in protein variation in cancer cells, shows research

A multi-center study led by The University of Texas MD Anderson Cancer Center has shed light on why proteins, the seedlings that serve as the incubator for many cancers, can vary from cancer to cancer and even patient to patient, a discovery that adds to a growing base of knowledge important for developing more effective precision therapies.

27 Apr 2018

Researchers use CRISPR/Cas9 technique to turn off gene that regulates cholesterol levels in adult mice

Biomedical engineers at Duke University have used a CRISPR/Cas9 genetic engineering technique to turn off a gene that regulates cholesterol levels in adult mice, leading to reduced blood cholesterol levels and gene repression lasting for six months after a single treatment.

27 Apr 2018

Western diets promote bacterial growth in the small intestine, increase fat digestion and absorption

A researcher at Midwestern University led a new study showing that Western diets, high in fat and simple sugar, promote the growth of bacteria in the small intestine that increase fat digestion and absorption.

27 Apr 2018

New CAR-T therapy could provide safer, more effective cancer treatment

There have been few cancer treatments with such a promising future as using the patient's own immune system.

27 Apr 2018

Zika virus can be used for treating aggressive human central nervous system tumors, shows study

A Brazilian study published April 26 in the journal Cancer Research shows for the first time in vivo that Zika virus can be used as a tool to treat aggressive human central nervous system (CNS) tumors.

27 Apr 2018

Study shows nitric oxide inhibits S. aureus bacteria from transforming to its virulent form

According to the U.S. Centers for Disease Control and Prevention, about one in three humans carries Staphylococcus aureus, or "staph," in our noses, and 2 percent of us carry the dreaded methicillin-resistant (MRSA) strain that thwarts common antibiotics.

27 Apr 2018

Study to examine whether cannabidiol provides therapeutic benefit to children with autism

Researchers at University of California San Diego School of Medicine are preparing a first-of-its-kind, multidisciplinary investigation to determine if and how cannabidiol, a non-psychoactive compound found in the cannabis plant, provides therapeutic benefit to children with severe symptoms of autism spectrum disorder.

27 Apr 2018

Researchers target and kill disease-causing bacteria using cocktail of viruses

Imagine that you have become ill because you have eaten some food that contained pathogenic bacteria. You keep running to the toilet and you may also throw up. You go to the doctor and are prescribed broad-spectrum antibiotics, which - in addition to killing the bad bacteria in your intestinal flora - carpet bomb the complex community of commensal bacteria forming a healthy intestinal flora.

26 Apr 2018

Researchers discover unique mechanism that drives spread of deadly infection

Scientists at the University of Birmingham have discovered a unique mechanism that drives the spread of a deadly infection.

26 Apr 2018

Chronic inflammation in middle age may increase risk of frailty decades later

A study of nearly 6,000 Americans followed for 24 years from middle to late adulthood found that having chronic inflammation in middle age may be linked to an increased risk of frailty and overall poorer health decades later.

26 Apr 2018

Research leads to new potential treatment for Hereditary Hemorrhagic Telangiectasia

The work of researchers Francesc Viñals and Mariona Graupera at the Bellvitge Biomedical Research Institute - Catalan Institute of Oncology - University of Barcelona, together with Dr. Antoni Riera-Mestre, has led to a new potential treatment for Hereditary Hemorrhagic Telangiectasia or Rendu-Osler Syndrome, a rare disease that affects blood vessels and had no described treatment.

26 Apr 2018

Advances in genetic testing give new insights to parents of children with epileptic encephalopathy

Advances in genetic testing offer new insights to parents who have a child with a rare but serious form of epilepsy, epileptic encephalopathy (EE), found in one of about every 2,000 births and characterized by developmental disabilities as well as horrible seizures.

26 Apr 2018

Researchers uncover how obesity leads to cancer in epithelial cells

A new study led by researchers at Hokkaido University has shown that obesity may enhance the progression of cancer, while aspirin may protect against it.

26 Apr 2018

New UCLA study could elucidate certain causes of infertility and miscarriage

A new study in the journal Nature Cell Biology has uncovered information about a key stage that human embryonic cells must pass through just before an embryo implants. The research, led by UCLA biologist Amander Clark, could help explain certain causes of infertility and spontaneous miscarriage.

26 Apr 2018

Researchers target telomerase for killing NRAS-mutant melanoma cells

Targeting telomerase was effective at killing NRAS-mutant melanoma cells, and the impact was further enhanced when the strategy was paired with an inhibitor of mitochondrial function, according to study results by The Wistar Institute published in Oncogene.

26 Apr 2018

Scientists improve growth of 3d brain models to better understand autism, dementia, schizophrenia

Salk Institute scientists recently have developed a method to make micro brain structures in the lab. These microbrain tissues are designated to be used in research for treatment of neurological diseases such as Alzheimer’s disease or Parkinson’s disease.

26 Apr 2018

B Cell News and Research

Scientists discover potential therapeutic target for devastating premature aging disease

Specific type of RNA editing plays key role in protein variation in cancer cells, shows research

Researchers use CRISPR/Cas9 technique to turn off gene that regulates cholesterol levels in adult mice

Western diets promote bacterial growth in the small intestine, increase fat digestion and absorption

New CAR-T therapy could provide safer, more effective cancer treatment

Zika virus can be used for treating aggressive human central nervous system tumors, shows study

Study shows nitric oxide inhibits S. aureus bacteria from transforming to its virulent form

Study to examine whether cannabidiol provides therapeutic benefit to children with autism

Researchers target and kill disease-causing bacteria using cocktail of viruses

Researchers discover unique mechanism that drives spread of deadly infection

Chronic inflammation in middle age may increase risk of frailty decades later

Research leads to new potential treatment for Hereditary Hemorrhagic Telangiectasia

Advances in genetic testing give new insights to parents of children with epileptic encephalopathy

Researchers uncover how obesity leads to cancer in epithelial cells

New UCLA study could elucidate certain causes of infertility and miscarriage

Researchers target telomerase for killing NRAS-mutant melanoma cells

Scientists improve growth of 3d brain models to better understand autism, dementia, schizophrenia

Exploiting rabies virus machinery to usher Parkinson's disease drug directly to the brain

Bacteria enhance antifungal drug resistance in early childhood caries

Scientists discover culprit in reducing effectiveness of insulin

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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