Clinical Trial News and Research

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How ketamine treatment elicits long-lasting anti-depressive effects

Researchers discuss the mechanisms responsible for the sustained antidepressant effects of ketamine by examining ketamine-NMDAR interactions.

20 Oct 2023

Study finds more mature gut microbiome in malnourished Nigerien children after antibiotic treatment

Malnutrition threatens the lives of millions of children under age 5, causing about 500,000 deaths per year in low- and middle-income countries.

19 Oct 2023

First-of-its kind hormone replacement therapy improves symptoms in patients with adrenal conditions

A first-of-its kind hormone replacement therapy that more closely replicates the natural circadian and ultradian rhythms of our hormones has shown to improve symptoms in patients with adrenal conditions.

19 Oct 2023

Potato starch supplement may help prevent gvhd in bone marrow transplant patients

Researchers at Baylor College of Medicine and the University of Michigan conducted a phase I pilot study to assess the feasibility of using potato starch as a dietary intervention to modify the gut microbiome in bone marrow transplant patients.

19 Oct 2023

Brain natriuretic peptide plays a role in activating atopic dermatitis

Researchers from North Carolina State University have pinpointed a particular peptide's role in activating atopic dermatitis, or eczema. The work could lead to more effective treatments for the condition.

19 Oct 2023

"Two-for-one" cancer immunotherapy more effective and at least as safe as standard treatments

A "two-for-one" cancer immunotherapy is potentially more effective and at least as safe as standard immunotherapies, physician-scientists from UPMC Hillman Cancer Center who led an international, early-phase clinical trial report today in the journal Nature Medicine.

19 Oct 2023

CAR T-cell therapy for multiple myeloma shows no difference in survival outcomes by race and ethnicity

Patients with multiple myeloma treated with idecabtagene vicleucel, known as "ide-cel," a chimeric antigen receptor (CAR) T-cell therapy, had no difference in overall survival outcomes regardless of race and ethnicity, according to a study published in Blood Advances.

19 Oct 2023

Study adds two new strains to the list of potential antihypertensive probiotics

An estimated 40% of the global adult population have high blood pressure, or hypertension, which puts people at risk of cardiovascular disease and other dangerous health conditions.

19 Oct 2023

Common challenges when seeking market access for rare disease therapies

In this interview, News Medical speaks to Donovan Quill, Executive Vice President of Growth & Strategy at AscellaHealth about the recurring challenges met when seeking market access for rare disease therapies.

From AscellaHealth, LLC. 19 Oct 2023

Can selenium and vitamin E supplementation prevent recurrence and progression of non–muscle-invasive bladder cancer?

The use of vitamin E and selenium in preventing the recurrence and progression of NMIBC.

19 Oct 2023

Study compares two widely used statins for treating patients with coronary artery disease

Two widely used statins, rosuvastatin and atorvastatin, are equally effective at preventing heart attacks, strokes and death in people with coronary artery disease.

18 Oct 2023

New institute to integrate food-based nutrition interventions into health care

A newly launched, first-of-its-kind institute aims to address a glaring gap in the medical system by working to integrate food-based nutrition interventions into health care to treat disease and advance health equity.

18 Oct 2023

Scientists identify two promising new treatment options for men with recurrent prostate cancer

Cedars-Sinai Cancer investigators have identified two promising new treatment options for men with recurrent prostate cancer - both of which helped patients live longer without their disease progressing than the current standard treatment.

18 Oct 2023

Surgery to straighten a crooked septum more effective than nasal sprays, trial suggests

Surgery to straighten a crooked septum (the thin wall of bone and cartilage dividing the space between the two nostrils) is more effective than nasal sprays, and should be offered to adults with at least moderate symptoms such as breathing disruption, suggests a UK trial published by The BMJ today.

18 Oct 2023

Precision oncology therapies account for nearly half of new cancer drug approvals since 1998

Of the 198 new oncology drugs approved by the U.S. Food and Drug Administration (FDA) between 1998 and 2022, approximately 43% were precision oncology therapies, the use of which is guided by biomarker testing.

18 Oct 2023

More antibiotics not better for preventing infection after joint replacement surgery, study finds

Knee and hip replacements are increasing globally due to an aging population. In the United States, the number of patients needing a joint replacement will exceed 2.7 million in the next 7 years.

18 Oct 2023

Researchers receive NCI grant for the development of new pancreatic cancer therapies

Researchers at Washington University School of Medicine in St. Louis have received an NCI grant that will provide about $10.9 million to research programs for the development of new therapies for pancreatic ductal adenocarcinoma, the deadliest form of pancreatic cancer.

17 Oct 2023

FAST joins with University of Pennsylvania to develop investigational AAV gene therapy for Angelman syndrome

The Foundation for Angelman Syndrome Therapeutics (FAST) announced today that the non-profit organization has entered into an exclusive global collaborative research and development agreement with the University of Pennsylvania to develop an investigational adeno-associated virus (AAV) gene therapy for Angelman syndrome (AS).

17 Oct 2023

New brain-wave cap diagnoses stroke in the ambulance, saving lives

A special brain-wave cap can diagnose stroke in the ambulance, allowing the patient to receive appropriate treatment faster.

17 Oct 2023

Promising breakthroughs ignite hope for a novel and effective Tuberculosis vaccine

The success and challenges of developing different tuberculosis (TB) vaccine types.

17 Oct 2023

Clinical Trial News and Research

How ketamine treatment elicits long-lasting anti-depressive effects

Study finds more mature gut microbiome in malnourished Nigerien children after antibiotic treatment

First-of-its kind hormone replacement therapy improves symptoms in patients with adrenal conditions

Potato starch supplement may help prevent gvhd in bone marrow transplant patients

Brain natriuretic peptide plays a role in activating atopic dermatitis

"Two-for-one" cancer immunotherapy more effective and at least as safe as standard treatments

CAR T-cell therapy for multiple myeloma shows no difference in survival outcomes by race and ethnicity

Study adds two new strains to the list of potential antihypertensive probiotics

Common challenges when seeking market access for rare disease therapies

Can selenium and vitamin E supplementation prevent recurrence and progression of non–muscle-invasive bladder cancer?

Study compares two widely used statins for treating patients with coronary artery disease

New institute to integrate food-based nutrition interventions into health care

Scientists identify two promising new treatment options for men with recurrent prostate cancer

Surgery to straighten a crooked septum more effective than nasal sprays, trial suggests

Precision oncology therapies account for nearly half of new cancer drug approvals since 1998

More antibiotics not better for preventing infection after joint replacement surgery, study finds

Researchers receive NCI grant for the development of new pancreatic cancer therapies

FAST joins with University of Pennsylvania to develop investigational AAV gene therapy for Angelman syndrome

New brain-wave cap diagnoses stroke in the ambulance, saving lives

Promising breakthroughs ignite hope for a novel and effective Tuberculosis vaccine

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