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Schizophrenia risk conferred by rare damaging genetic variants is conserved across ethnicities

Researchers have identified two previously unknown genes linked to schizophrenia and newly implicated a third gene as carrying risk for both schizophrenia and autism.

13 Mar 2023

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut's microbial environment.

13 Mar 2023

Redoubling efforts to highlight the importance of colorectal cancer screening

With the arrival of March, Colorectal Cancer Awareness Month, faculty and staff in the Department of Internal Medicine's Section of Digestive Diseases are redoubling their efforts to spread the word about the importance of screening, especially in younger individuals and those with a family history of the disease.

10 Mar 2023

New insights into how spider lily compound kills cancer cells while keeping healthy cells intact

A scientific instrument at the Department of Energy's Oak Ridge National Laboratory could help create a noninvasive cancer treatment derived from a common tropical plant.

10 Mar 2023

New ultrasound method can measure a key indicator of abnormal tissue and disease

A new ultrasound method that can measure the level of tension in human tissue for the first time - a key indicator of disease - has been developed by researchers from the University of Sheffield.

10 Mar 2023

A small protein could provide a revolutionary approach to tackling obesity-related diseases

Research published today shows that a peptide (small protein) called PEPITEM could provide a revolutionary approach to reducing the risk of type 2 diabetes and other obesity-related diseases such as hepatic steatosis (fatty liver).

9 Mar 2023

Inhibition of ACLY by 326E represents a promising strategy for treatment of hypercholesterolemia

This new article publication from Acta Pharmaceutica Sinica B, discusses the development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia.

9 Mar 2023

What is the gastrointestinal impact of Long Covid?

Researchers assessed gastrointestinal outcomes associated with COVID-19.

9 Mar 2023

COVID-19 patients at increased risk of developing gastrointestinal disorders

People who have had COVID-19 are at increased risk of developing gastrointestinal (GI) disorders within a year after infection compared with people who haven't been infected, according to an analysis of federal health data by researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care system.

8 Mar 2023

Discovery could lead to effective treatments for acute alcohol intoxication

A shot of a liver-produced hormone called FGF21 sobered up mice that had passed out from alcohol, allowing them to regain consciousness and coordination much faster than those that didn't receive this treatment, UT Southwestern researchers report in a new study.

8 Mar 2023

A shot of liver-produced hormone sobers up drunk mice

A hormone called fibroblast growth factor 21 (FGF21) protects mice against ethanol-induced loss of balance and righting reflex, according to a study publishing on March 7 in the journal Cell Metabolism.

7 Mar 2023

FDA mandate to limit the dosage of acetaminophen linked to reductions in serious liver injury

A United States Food and Drug Administration mandate to limit the dosage of acetaminophen in pills that combine acetaminophen and opioid medications is significantly associated with subsequent reductions in serious liver injury, according to a study led by investigators at the University of Alabama and Weill Cornell Medicine.

7 Mar 2023

Prevalence and clinical outcomes of viral and bacterial coinfections in hospitalized COVID-19 patients

In a recent study, researchers analyzed the occurrence of bacterial and viral infections in adults hospitalized with coronavirus disease 2019 (COVID-19) to determine the clinical and demographic features, outcomes, and microbial spectrums associated with bacterial coinfections and the prevalence of viral coinfections.

7 Mar 2023

The effect of strawberry, blueberry, and strawberry-blueberry blend decoction-based functional beverages on obesity-related metabolic alterations

Researchers evaluated whether polyphenol-rich strawberry and blueberry decoction-based functional beverages could prevent obesity or related metabolic alterations in high-fat and high-fructose diet-fed rats.

7 Mar 2023

CDC recommendations and clinical considerations for the treatment of severe Mpox

In a recent article published in the United States (U.S.) Centers for Disease Control and Prevention's (CDC) Morbidity and Mortality Weekly Report, a team of researchers discussed the medical countermeasures and clinical considerations for treating severe manifestations of Mpox.

6 Mar 2023

Erratic sleep patterns may increase blood pressure among teens who have more abdominal fat

Staying awake later into the night and sleeping in on the weekends are hallmarks of adolescent behavior, however, erratic sleep patterns may have consequences for future heart health by increasing blood pressure among teens who have more abdominal fat, according to new research published today in Hypertension, an American Heart Association journal.

6 Mar 2023

How does chronic HBV infection affect flu and COVID-19 vaccine responses?

The influenza season marks the beginning of a time of illness, sometimes serious or even fatal, in much of the world. For this reason, flu shots are recommended, especially for individuals with underlying diseases such as chronic hepatitis B (CHB) infection, since they are at higher risk for adverse outcomes.

6 Mar 2023

Virtual or in person: Which kind of doctor’s visit is better, and when it matters

When the covid-19 pandemic swept the country in early 2020 and emptied doctors' offices nationwide, telemedicine was suddenly thrust into the spotlight. Patients and their physicians turned to virtual visits by video or phone rather than risk meeting face-to-face.

6 Mar 2023

Keto-like diet may be associated with elevated risk of cardiovascular events

The ketogenic or "keto" diet, which involves consuming very low amounts of carbohydrates and high amounts of fats, has been gaining popularity.

5 Mar 2023

Naked mRNA delivered using needle-free PYRO injection presents a safe and effective potential vaccination method

Researchers examined the vaccination effects and local antigen expression efficiency of a needle-free vaccination technique involving pyro-drive liquid jet injection (PYRO) to deliver the naked messenger ribonucleic acid (mRNA) to the skin.

3 Mar 2023

Liver News and Research

Schizophrenia risk conferred by rare damaging genetic variants is conserved across ethnicities

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Redoubling efforts to highlight the importance of colorectal cancer screening

New insights into how spider lily compound kills cancer cells while keeping healthy cells intact

New ultrasound method can measure a key indicator of abnormal tissue and disease

A small protein could provide a revolutionary approach to tackling obesity-related diseases

Inhibition of ACLY by 326E represents a promising strategy for treatment of hypercholesterolemia

What is the gastrointestinal impact of Long Covid?

COVID-19 patients at increased risk of developing gastrointestinal disorders

Discovery could lead to effective treatments for acute alcohol intoxication

A shot of liver-produced hormone sobers up drunk mice

FDA mandate to limit the dosage of acetaminophen linked to reductions in serious liver injury

Prevalence and clinical outcomes of viral and bacterial coinfections in hospitalized COVID-19 patients

The effect of strawberry, blueberry, and strawberry-blueberry blend decoction-based functional beverages on obesity-related metabolic alterations

CDC recommendations and clinical considerations for the treatment of severe Mpox

Erratic sleep patterns may increase blood pressure among teens who have more abdominal fat

How does chronic HBV infection affect flu and COVID-19 vaccine responses?

Virtual or in person: Which kind of doctor’s visit is better, and when it matters

Keto-like diet may be associated with elevated risk of cardiovascular events

Naked mRNA delivered using needle-free PYRO injection presents a safe and effective potential vaccination method

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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