Protein C News and Research

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Researchers discover how of EBV virus takes over human cells gene regulating machinery

University of Montreal researchers have discovered how a component of the Epstein Barr (EBV) virus takes over our cells gene regulating machinery, allowing the virus to replicate itself.

10 Apr 2014

IRB Barcelona scientists develop new drug target to prevent muscle deterioration in certain diseases

In the study published today in the Journal of Clinical Investigation (JCI), one of the journals with highest impact in experimental medicine, the researchers associate the activity of the DOR protein with muscle atrophy and point to DOR as a plausible target against which to develop a drug to prevent muscle deterioration in certain diseases.

10 Apr 2014

Researcher develops synthetic hydrogel that promotes natural clotting, heals surgical wounds

Synthetic collagen invented at Rice University may help wounds heal by directing the natural clotting of blood.

10 Apr 2014

Vibrational spectroscopy opens up new ways to diagnose chronic diseases

In today’s ageing population, resulting in a rising prevalence of chronic diseases such as neurodegeneration, the need for simple, non-invasive methods to diagnose or screen for important medical conditions becomes more and more relevant. Objective and cost-effective approaches capable of diagnosing early-stage disease in point-of-care clinical settings are necessary to facilitate the personalising of therapies to prevent or slow down pathology development.

10 Apr 2014

Research finding sheds more light on cancer development and metastasis

The push and pull of physical force can cause profound changes in the behavior of a cell. Two studies from researchers working at the UNC Lineberger Comprehensive Cancer Center reveal how cells respond to mechanical manipulation, a key factor in addressing the underlying causes of cancer and other diseases.

10 Apr 2014

Study shows dabrafenib has no added benefit in comparison with dacarbazine

Dabrafenib (trade name: Tafinlar) has been approved since August 2013 for the treatment of advanced melanoma. In January 2014, in an early benefit assessment pursuant to the "Act on the Reform of the Market for Medicinal Products" (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) had determined that dabrafenib has no added benefit in comparison with dacarbazine.

10 Apr 2014

Moffitt Cancer Center initiates phase I clinical trial of cancer vaccine ID-G305

Moffitt Cancer Center has initiated a phase I clinical trial for a new immunotherapy drug, ID-G305, made by Immune Design. Immunotherapy is a treatment option that uses a person's own immune system to fight cancer. It has several advantages over standard cancer therapies, including fewer side effects and an overall better tolerability. It tends to be most effective in patients who have smaller, localized tumors that have not spread to distant sites.

10 Apr 2014

Novel discovery could lead to new therapy to combat obesity, diabetes

By manipulating a biochemical process that underlies cells' energy-burning abilities, investigators at Beth Israel Deaconess Medical Center have made a novel discovery that could lead to a new therapy to combat obesity and diabetes.

10 Apr 2014

University of Montreal scientists discover molecular details of kissing disease virus attacks

University of Montreal researchers have discovered how a component of the Epstein Barr (EBV) virus takes over our cells gene regulating machinery, allowing the virus to replicate itself.

10 Apr 2014

Rice University research targets Parkinson's, Huntington's and other proteasomal diseases

Synthetic genetic circuitry created by researchers at Rice University is helping them see, for the first time, how to regulate cell mechanisms that degrade the misfolded proteins implicated in Parkinson's, Huntington's and other diseases.

9 Apr 2014

Scientists to develop handheld testing device to provide same day diagnosis from patient's bedside

Scientists at the University of Southampton are aiming to develop a handheld testing device to provide same day diagnosis from a patient's bedside.

9 Apr 2014

Research opens new possibilities for blocking runaway cell division in cancer

The structure of a key part of the machinery that allows cells to divide has been identified by researchers at the University of California, Davis -- opening new possibilities for throwing a wrench in the machine and blocking runaway cell division in cancer.

9 Apr 2014

Research shows blocking DNA repair improves radiation therapy for glioblastomas

UT Southwestern Medical Center researchers have demonstrated in both cancer cell lines and in mice that blocking critical DNA repair mechanisms could improve the effectiveness of radiation therapy for highly fatal brain tumors called glioblastomas.

9 Apr 2014

New lab at the Nencki Institute conducts research on neurodegenerative diseases

The Laboratory of Preclinical Studies of Higher Standard, the newest lab of the Neurobiology Center at the Nencki Institute in Warsaw, Poland, will conduct basic research aimed to explain molecular mechanisms responsible for neurodegenerative diseases.

9 Apr 2014

Researcher wins 2014 Abraham White Distinguished Science Award for contributions in treatment of neurological diseases

Michael Chopp, Ph.D., scientific director of the Henry Ford Neuroscience Institute at Henry Ford Hospital, won the 2014 Abraham White Distinguished Science Award for his discovery of the role of a protein in the treatment of brain injuries and neurodegenerative diseases.

9 Apr 2014

Herpes simplex viral therapy in conjunction with radiation proves effective in treating malignant gliomas

Researchers at the University of Alabama at Birmingham report a genetically engineered herpes simplex viral therapy is safe when used in conjunction with radiation in the treatment of malignant gliomas, one of the most deadly forms of brain cancer.

9 Apr 2014

Study shows critical role of immune system in protecting against viruses and cancer cells

A team of researchers at the IRCM, led by Andr- Veillette, MD, explains how our immune system kills abnormal blood cells. Their discovery, recently published in the Journal of Experimental Medicine, could eventually lead to new treatment avenues for leukemia, lymphoma and certain types of infectious viral diseases.

9 Apr 2014

Study provides insights into why alcohol has negative effect on wound healing

People who are injured while binge drinking are much slower to heal from wounds suffered in car accidents, shootings, fires, etc.

9 Apr 2014

Researchers find new molecular targets for aggressive brain tumor

Researchers from the Geisel School of Medicine at Dartmouth will present a scientific poster on Tuesday, April 8, 2014 at the American Association of Cancer Researchers conference in San Diego, CA. The research identifies a potential characteristic for predicting outcome in a deadly form of brain cancer known as glioblastoma multiforme.

9 Apr 2014

Researchers demonstrate advantages of HOPE fixation strategy

They discovered that the so-called HOPE method allows tissue samples to be treated such that they do not only meet the requirements of clinical histology, but can still be characterised later on by modern methods of proteomics, a technique analysing all proteins at once.

9 Apr 2014

Protein C News and Research

Researchers discover how of EBV virus takes over human cells gene regulating machinery

IRB Barcelona scientists develop new drug target to prevent muscle deterioration in certain diseases

Researcher develops synthetic hydrogel that promotes natural clotting, heals surgical wounds

Vibrational spectroscopy opens up new ways to diagnose chronic diseases

Research finding sheds more light on cancer development and metastasis

Study shows dabrafenib has no added benefit in comparison with dacarbazine

Moffitt Cancer Center initiates phase I clinical trial of cancer vaccine ID-G305

Novel discovery could lead to new therapy to combat obesity, diabetes

University of Montreal scientists discover molecular details of kissing disease virus attacks

Rice University research targets Parkinson's, Huntington's and other proteasomal diseases

Scientists to develop handheld testing device to provide same day diagnosis from patient's bedside

Research opens new possibilities for blocking runaway cell division in cancer

Research shows blocking DNA repair improves radiation therapy for glioblastomas

New lab at the Nencki Institute conducts research on neurodegenerative diseases

Researcher wins 2014 Abraham White Distinguished Science Award for contributions in treatment of neurological diseases

Herpes simplex viral therapy in conjunction with radiation proves effective in treating malignant gliomas

Study shows critical role of immune system in protecting against viruses and cancer cells

Study provides insights into why alcohol has negative effect on wound healing

Researchers find new molecular targets for aggressive brain tumor

Researchers demonstrate advantages of HOPE fixation strategy

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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