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Gene-based method for selecting doses of warfarin no better than standardized dosing methods

A new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania has determined that a gene-based method for selecting patients' doses of the popular heart medication warfarin is no better than standardized dosing methods. The study was presented today at the 2013 Scientific Sessions of the American Heart Association and published simultaneously in the New England Journal of Medicine.

20 Nov 2013

Tasquinimod drug effective for men with metastatic castration-resistant prostate cancer

An investigational prostate cancer treatment slows the disease's progression and may increase survival, especially among men whose cancer has spread to the bones, according an analysis led by the Duke Cancer Institute.

20 Nov 2013

HIPAA-secure social network launched solely for Autism community

Autism Spectrum Disorder is the fastest growing developmental disability in the United States, affecting 1 in 88 children, according to the CDC. As more families struggle to find answers and make sense of a diagnosis, National Autism Network announces the launch of an innovative, HIPAA-secure social network designed specifically and solely for the Autism community. This fully integrated social network offers features not currently found on any social network and was created to fill a void in the community.

20 Nov 2013

First patients enrolled in EF-21 Study of NovoTTF Therapy for brain metastases from NSCLC cancer

Novocure announced today that the first patients have enrolled in the EF-21 Study, a prospective randomized clinical study of NovoTTF Therapy for patients with brain metastases from non-small cell lung carcinoma cancer. NovoTTF Therapy is an anti-mitotic treatment delivered continuously throughout the day by the NovoTTF-100A System.

20 Nov 2013

Serametrix launches new MDSC-based blood test for cancer patients

Serametrix Corporation has announced the launch of an important new blood test for cancer patients. The test measures a patient's level of circulating Myeloid Derived Suppressor Cells (MDSCs) that are known to decrease anti-tumor immunity and are associated with poor survival rates in cancer patients.

20 Nov 2013

Loyola University initiates clinical trial of vaccine that trains immune system to fight melanoma

Loyola University Medical Center is enrolling melanoma patients in the first clinical trial in the Midwest of an experimental vaccine that trains a patient's immune system to fight the deadly cancer.

20 Nov 2013

Researchers report long-term benefits of gene therapy in advanced heart failure patients

Researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai reported the long-term benefits of a single dose of their gene therapy AAV1/SERCA2a in advanced heart failure patients on Nov. 19 at the American Heart Association Scientific Sessions 2013.

20 Nov 2013

Once-daily edoxaban prevents stroke in patients with atrial fibrillation

According to the United States Centers for Disease Control and Prevention, over 800,000 Americans die each year from heart disease and stroke. Stroke is the leading cause of serious long-term disability and death in the US. In addition to lifestyle changes, medications such as anti-blood clotting drugs are helpful in the prevention of stroke.

20 Nov 2013

Study: Most popular apps for iPhones lack some basic strategies to help smokers quit

An estimated 11 million smokers in the United States own a smartphone and increasingly they're turning to apps in an attempt to quit. But many of the most popular anti-smoking apps for iPhones or Androids lack some basic strategies that are known to help smokers quit, according to a new study in the American Journal of Preventive Medicine.

20 Nov 2013

UC San Diego study suggests racial inequality leads to higher mortality in cancer patients

Researchers at the University of California, San Diego School of Medicine say metastatic colorectal cancer patients of African-American descent are less likely to be seen by cancer specialists or receive cancer treatments. This difference in treatment explains a large part of the 15 percent higher mortality experienced by African-American patients than non-Hispanic white patients.

20 Nov 2013

Bipolar disorder treatment nonadherence ‘needs more attention’

More than half of patients with bipolar disorder fail to take their medication as prescribed, a study of Finnish inpatients and outpatients has found.

19 Nov 2013

Brain signals in fibromyalgia patients: an interview with Dr. Marco Loggia from Massachusetts General Hospital and Harvard Medical School in Boston

Fibromyalgia patients suffer from a variety of symptoms, including widespread body pain and myofascial tenderness. They are ‘hyperalgesic’, which means that if you give them a stimulus that in healthy subjects is just mildly painful (or even completely innocuous), they may perceive it as excruciatingly painful.

19 Nov 2013

Heart failure patients receiving LVAD may benefit from injection of powerful cells directly into heart

A multicenter team of researchers within the NIH-funded Cardiothoracic Surgical Trials Network, led by Icahn School of Medicine at Mount Sinai, have found end-stage heart failure patients who receive a surgically implanted left ventricular assist device heart pump may also benefit from a single dose of millions of powerful cells injected directly into their heart during surgery.

19 Nov 2013

First Edition: November 19, 2013

Today's headlines include news that Obama administration officials were warned about the possibility of website difficulties months ago by an outside consulting firm.

19 Nov 2013

Study on women's preferences, decision-making patterns regarding treatment for depression during, after pregnancy

Women with depression in the perinatal period experience a high degree of conflict in deciding whether and how to treat their depression, but strongly prefer treatments other than antidepressant medications, reports a study in the November Journal of Psychiatric Practice®. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

19 Nov 2013

GM-CSF therapy does not improve treadmill walking time in patients with peripheral artery disease

Joseph Poole, M.D., Ph.D., of the Emory University School of Medicine, Atlanta, and colleagues studied whether therapy with granulocyte-macrophage colony stimulating factor (GM-CSF), an agent that functions as a white blood cell growth factor, would improve walking performance in patients with symptomatic peripheral artery disease (a form of vascular disease in which there is partial or total blockage of an artery, usually one leading to a leg or arm).

19 Nov 2013

Study finds patients treated with varespladib drug more likely to experience cardiovascular events

Patients with acute coronary syndrome who were treated with the experimental drug varespladib were more likely to experience additional cardiovascular events - including sudden death, heart attack and stroke - than those treated with placebo, according to research from the Cleveland Clinic Coordinating Center for Clinical Research (C5Research).

19 Nov 2013

Therapy News and Research

Gene-based method for selecting doses of warfarin no better than standardized dosing methods

Tasquinimod drug effective for men with metastatic castration-resistant prostate cancer

HIPAA-secure social network launched solely for Autism community

First patients enrolled in EF-21 Study of NovoTTF Therapy for brain metastases from NSCLC cancer

Serametrix launches new MDSC-based blood test for cancer patients

Loyola University initiates clinical trial of vaccine that trains immune system to fight melanoma

Researchers report long-term benefits of gene therapy in advanced heart failure patients

Once-daily edoxaban prevents stroke in patients with atrial fibrillation

Study: Most popular apps for iPhones lack some basic strategies to help smokers quit

UC San Diego study suggests racial inequality leads to higher mortality in cancer patients

Bipolar disorder treatment nonadherence ‘needs more attention’

Brain signals in fibromyalgia patients: an interview with Dr. Marco Loggia from Massachusetts General Hospital and Harvard Medical School in Boston

Heart failure patients receiving LVAD may benefit from injection of powerful cells directly into heart

First Edition: November 19, 2013

Study on women's preferences, decision-making patterns regarding treatment for depression during, after pregnancy

GM-CSF therapy does not improve treadmill walking time in patients with peripheral artery disease

Study finds patients treated with varespladib drug more likely to experience cardiovascular events

Boston Scientific gets CE Mark approval for Vercise Deep Brain Stimulation System

Orthopaedic specialist offers tips to prevent painful holiday season

University of Wisconsin scientist to present revolutionary stem cell technology to Australian bioindustry

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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