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Scientists find inhibiting action of BRD4 protein may eradicate rare type of soft-tissue cancer

A deadly, rare type of soft-tissue cancer may be completely eradicated simply by inhibiting a key protein involved in its growth, UT Southwestern Medical Center researchers report.

27 Dec 2013

Experts to share insights on the integration of science, psychotherapy and spirituality

Neuroscience is the new buzzword in the world of psychotherapy, yet distinguishing between true innovation and mere speculation can be difficult. In a new program at the 2014 iaedp Symposium in St. Petersburg, Florida (February 26-March 2), keynote speakers, Carolyn Costin, MFt, MA, MEd, CEDS and Joan Borysenko, PhD, will share their insights on the integration of science, psychotherapy and spirituality.

27 Dec 2013

Surgery offers better survival, functional outcomes than chemotherapy for patients with tongue cancer

Patients with tongue cancer who started their treatment with a course of chemotherapy fared significantly worse than patients who received surgery first, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.

27 Dec 2013

Activation of protein P300 plays central role in DNA repair in hippocampal neurons

Various medications have been developed to treat neurodegenerative disorders, and drugs without significant side effects are gaining widespread interest such disorders.

27 Dec 2013

Combination of medication and psychological therapy effective for treating chronic migraines in children

Psychological therapy plus medication appears to be the most effective treatment strategy for chronic migraine in children, but it may take time for the medical system to widely adopt this approach, says an editorial in the current issue of the Journal of the American Medical Association by Mark Connelly, PhD, a pain psychologist and co-director of the Comprehensive Headache Clinic at Children's Mercy Hospital.

26 Dec 2013

Genetics of rheumatoid arthritis contributes to biology and drug discovery

The results of the largest international study to date into the genetic basis of rheumatoid arthritis shed light on the biology of the disease and provide evidence that large-scale genetic studies can assist in the identification of new drugs for complex disorders such as rheumatoid arthritis.

26 Dec 2013

Researchers uncover new genetic clue that contributes to increased risk of type 2 diabetes

An international team of researchers in Mexico and the United States has uncovered a new genetic clue that contributes to an increased risk of developing type 2 diabetes, particularly the elevated risk among Mexican and other Latin American populations.

26 Dec 2013

Prolonged exposure therapy shows greater benefit adolescent girls with sexually abused PTSD

Adolescents girls with sexual abuse-related posttraumatic stress disorder (PTSD) experienced greater benefit from prolonged exposure therapy (a type of therapy that has been shown effectiveness for adults) than from supportive counseling, according to a study appearing in the December 25 issue of JAMA.

26 Dec 2013

CAC screening plays more prominent role in determining risk for heart attack and stroke

A new study shows that coronary artery calcium (CAC) screening, an assessment tool that is not currently recommended for people considered at low risk, should play a more prominent role in helping determine a person’s risk for heart attack and heart disease-related death, as well as the need for angioplasty or bypass surgery.

26 Dec 2013

Researchers complete genomic analysis of cervical cancer in two patient populations

Researchers from the Boston area, Mexico, and Norway have completed a comprehensive genomic analysis of cervical cancer in two patient populations. The study identified recurrent genetic mutations not previously found in cervical cancer, including at least one for which targeted treatments have been approved for other forms of cancer.

25 Dec 2013

Madison Dearborn Partners signs definitive agreement to acquire Ikaria

Madison Dearborn Partners announced today that it has signed a definitive agreement under which it will acquire a majority ownership position in Ikaria, Inc., a leading provider of proprietary and innovative therapies for the critical care units in hospitals.

25 Dec 2013

Cognitive behavioral therapy reduces headache frequency, migraine-related disability in children

Among children and adolescents with chronic migraine, the use of cognitive behavioral therapy resulted in greater reductions in headache frequency and migraine-related disability compared with headache education, according to a study appearing in the December 25 issue of JAMA.

25 Dec 2013

Prolonged exposure therapy shows greater success for treating adolescent PTSD patients

Researchers at Penn Medicine report in the December 25 issue of JAMA that a modified form of prolonged exposure therapy - in which patients revisit and recount aloud their trauma-related thoughts, feelings and situations - shows greater success than supportive counseling for treating adolescent PTSD patients who have been sexually abused.

25 Dec 2013

Cell transplantation, gene therapy combination to open new therapeutic avenues for Alzheimer's disease

In a recent study published in the Neural Regeneration Research (Vol. 8, No. 33, 2013), Prof. Feng Li and team from Zhongshan School of Medicine, Sun Yat-sen University in China, synthesized a 19-nt oligonucleotide targeting BACE1, the key enzyme in amyloid beta protein (Aβ) production, and introduced it into the pSilenCircle vector to construct a short hairpin (shRNA) expression plasmid against the BACE1 gene.

24 Dec 2013

Concordia Healthcare acquires Pinnacle Biologics

Concordia Healthcare Corp., an integrated, specialty healthcare company focused on the acquisition of legacy pharmaceutical products and medical devices and the acquisition and/or development of orphan drugs, announced today that it has acquired Pinnacle Biologics, Inc., a U.S.-based biopharmaceutical company specializing in legacy pharmaceuticals which have the potential for development as orphan drugs to treat cancer indications in addition to those for which they have previously been approved.

24 Dec 2013

Healthcare workers' hands contaminated with C. difficile after routine care, study shows

A new study finds nearly one in four healthcare workers' hands were contaminated with Clostridium difficile spores after routine care of patients infected with the bacteria. The study was published in the January issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

24 Dec 2013

Treating depression fails to reverse cognitive deficits in bipolar disorder

Successful treatment of depression with total sleep deprivation does not improve neuropsychologic deficits in bipolar patients, despite improving clinical symptoms, Italian researchers report.

24 Dec 2013

Transplanting self-donated Schwann cells aids hind limb functional recovery

A study carried out at the University of Miami Miller School of Medicine for "The Miami Project to Cure Paralysis" has found that transplanting self-donated Schwann cells (SCs, the principal ensheathing cells of the nervous system) that are elongated so as to bridge scar tissue in the injured spinal cord, aids hind limb functional recovery in rats modeled with spinal cord injury.

24 Dec 2013

Researchers identify potential therapy for meibomian gland dysfunction

Meibomian gland dysfunction is the leading cause of dry eye disease, which affects tens of millions of Americans. However, there is no FDA-approved treatment for MGD. Researchers from the Schepens Eye Research Institute/Massachusetts Eye and Ear and Harvard Medical School have just identified a potential therapy.

24 Dec 2013

Researchers report new gene delivery method that targets tumor blood vessels

Working in mice, researchers at Washington University School of Medicine in St. Louis report developing a gene delivery method long sought in the field of gene therapy: a deactivated virus carrying a gene of interest that can be injected into the bloodstream and make its way to the right cells.

24 Dec 2013

Therapy News and Research

Scientists find inhibiting action of BRD4 protein may eradicate rare type of soft-tissue cancer

Experts to share insights on the integration of science, psychotherapy and spirituality

Surgery offers better survival, functional outcomes than chemotherapy for patients with tongue cancer

Activation of protein P300 plays central role in DNA repair in hippocampal neurons

Combination of medication and psychological therapy effective for treating chronic migraines in children

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Researchers uncover new genetic clue that contributes to increased risk of type 2 diabetes

Prolonged exposure therapy shows greater benefit adolescent girls with sexually abused PTSD

CAC screening plays more prominent role in determining risk for heart attack and stroke

Researchers complete genomic analysis of cervical cancer in two patient populations

Madison Dearborn Partners signs definitive agreement to acquire Ikaria

Cognitive behavioral therapy reduces headache frequency, migraine-related disability in children

Prolonged exposure therapy shows greater success for treating adolescent PTSD patients

Cell transplantation, gene therapy combination to open new therapeutic avenues for Alzheimer's disease

Concordia Healthcare acquires Pinnacle Biologics

Healthcare workers' hands contaminated with C. difficile after routine care, study shows

Treating depression fails to reverse cognitive deficits in bipolar disorder

Transplanting self-donated Schwann cells aids hind limb functional recovery

Researchers identify potential therapy for meibomian gland dysfunction

Researchers report new gene delivery method that targets tumor blood vessels

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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