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Direct oral anticoagulant does not appear to offer protection against severe COVID-19

DOAC (direct oral anticoagulant) pills are used in the treatment of atrial fibrillation by preventing blood clots. Even though blood clots are thought to contribute to complications from the new coronavirus infection, users of this class of drug do not seem to be protected against severe COVID-19, reports a large Swedish registry study from Karolinska Institutet published in The Journal of Internal Medicine.

1 Dec 2020

Experimental stem cell gene therapy may give a new lease of life for patient with sickle cell disease

"But it's a marathon whereas you keep going, the trail gets rockier and then you lose your shoes," the 27-year-old said. "It gets harder as you get older. Things start to fail and all you can think about is how much worse it's going to get down the road."

1 Dec 2020

Inpatient consultation service could reduce health care costs, hospital admissions in pediatric intensive care

When medically complex children are hospitalized, linking hospitalists to their regular outpatient providers through an inpatient consultation service were more likely to improve outcomes, according to researchers at The University of Texas Health Science Center at Houston (UTHealth).

1 Dec 2020

Researchers successfully edit SIV virus from genomes of non-human primates

Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.

1 Dec 2020

Study demonstrates safety of novel immuno-oncology therapy in patients with advanced solid tumors

A novel therapy designed to help stimulate the body's immune system response against cancer appears to be safe to use as alone or in combination with immune checkpoint inhibitors.

1 Dec 2020

Study shows critically ill patients are not seeking care for fear of COVID-19 infection

During the early days of the COVID-19 pandemic in New England, emergency department visits for medical emergencies - including psychiatric problems, trauma and heart attacks - declined by nearly a third, raising concerns among clinicians that critically ill patients were not seeking the care they needed for fear of coronavirus infection.

1 Dec 2020

Cost of prostate cancer treatment can be a major source of stress for men, their families

For men with early-stage prostate cancer, choices about initial treatment carry varying risks of "financial toxicity," reports a study in The Journal of Urology®, Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.

1 Dec 2020

New reviews provide timely updates for scholars, professionals focused on antimicrobial research

The initial chapter of 'Anti-infective Research and Development: Updates on Infection Mechanisms and Treatments' covers the mode of action of natural antimycobacterial compounds such as nordihydroguaiaretic acid, α-mangostin and allicin, as well as antimicrobial peptides and their role in the innate and adaptive immune response leading to the decrease of microbial resistance.

1 Dec 2020

New study could make chemical syntheses more sustainable for future generations

Pharmaceuticals, plastics, and many other chemical products have transformed human life. To prepare these products, chemists often use a catalyst--frequently based on rare metals--at various points in their syntheses.

1 Dec 2020

Nucleic acid-hydrolyzing scFv 3D8 exhibits potent antiviral effects on SARS-CoV-2

3D8, a 27-kDa recombinant antibody fragment, was found in autoimmune-prone Murphy Roths Large mice. The single-chain variable fragment (scFv) has the nucleic acid hydrolyzing activity and is shown to degrade DNA or mRNA of viruses in infected cells.

30 Nov 2020

Low-income black households disproportionately affected by Covid-19 shutdowns

The alarming rate at which Covid-19 has killed Black Americans has highlighted the deeply embedded racial disparities in the U.S. health care system.

30 Nov 2020

Financial symptoms could be used as early predictors of dementia

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health and the Federal Reserve Board of Governors found that Medicare beneficiaries who go on to be diagnosed with dementia are more likely to miss payments on bills as early as six years before a clinical diagnosis.

30 Nov 2020

Infection control, widespread testing help reduce SARS-CoV-2 transmission in schools, study finds

Now, a team of researchers at the New York University Grossman School of Medicine explored which school policies had the most significant impact on reducing the risk of in-school SARS-CoV-2 transmission.

30 Nov 2020

Researchers reveal how SARS-CoV-2 reaches the brain

Using post-mortem tissue samples, a team of researchers from Charité - Universitätsmedizin Berlin have studied the mechanisms by which the novel coronavirus can reach the brains of patients with COVID-19, and how the immune system responds to the virus once it does.

30 Nov 2020

Wyss Institute’s eRapid technology licensed to The iQ Group Global

Today, the Wyss Institute for Biologically Inspired Engineering at Harvard University announced that its eRapid technology has been licensed to The iQ Group Global for COVID-19 diagnostic applications.

30 Nov 2020

Researchers reveal link between gut bacteria and vitamin D levels

Our gut microbiomes -- the many bacteria, viruses and other microbes living in our digestive tracts -- play important roles in our health and risk for disease in ways that are only beginning to be recognized.

30 Nov 2020

SARS-CoV-2 immunity in the U.S. remains low

Seroprevalence studies indicate that less than 10% of people in the U. S. have detectable antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from July to September 2020.

30 Nov 2020

Study: Plant-based diet boosts metabolism

A plant-based diet boosts after-meal burn, leads to weight loss, and improves cardiometabolic risk factors in overweight individuals, according to a new randomized control trial published in JAMA Network Open by researchers with the Physicians Committee for Responsible Medicine.

30 Nov 2020

HIV and TB laboratory systems used to scale up COVID-19 testing in Africa

Many countries in resource-limited settings have high HIV, malaria, tuberculosis, hepatitis, and/or sexually transmitted infection (STI) burdens.

30 Nov 2020

Review highlights huge inconsistencies in palliative care provision across the globe

A major review of palliative care services around the world has highlighted huge inconsistencies in provision, with patients in some countries receiving a fraction of the support provided elsewhere.

30 Nov 2020

Medicine News and Research

Direct oral anticoagulant does not appear to offer protection against severe COVID-19

Experimental stem cell gene therapy may give a new lease of life for patient with sickle cell disease

Inpatient consultation service could reduce health care costs, hospital admissions in pediatric intensive care

Researchers successfully edit SIV virus from genomes of non-human primates

Study demonstrates safety of novel immuno-oncology therapy in patients with advanced solid tumors

Study shows critically ill patients are not seeking care for fear of COVID-19 infection

Cost of prostate cancer treatment can be a major source of stress for men, their families

New reviews provide timely updates for scholars, professionals focused on antimicrobial research

New study could make chemical syntheses more sustainable for future generations

Nucleic acid-hydrolyzing scFv 3D8 exhibits potent antiviral effects on SARS-CoV-2

Low-income black households disproportionately affected by Covid-19 shutdowns

Financial symptoms could be used as early predictors of dementia

Infection control, widespread testing help reduce SARS-CoV-2 transmission in schools, study finds

Researchers reveal how SARS-CoV-2 reaches the brain

Wyss Institute’s eRapid technology licensed to The iQ Group Global

Researchers reveal link between gut bacteria and vitamin D levels

SARS-CoV-2 immunity in the U.S. remains low

Study: Plant-based diet boosts metabolism

HIV and TB laboratory systems used to scale up COVID-19 testing in Africa

Review highlights huge inconsistencies in palliative care provision across the globe

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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