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Researchers identify novel protein that explains how biological clocks regulate human sleep

In a series of experiments sparked by fruit flies that couldn't sleep, Johns Hopkins researchers say they have identified a mutant gene - dubbed "Wide Awake" - that sabotages how the biological clock sets the timing for sleep.

17 Mar 2014

Study suggests effective therapeutics for IBD may hinge on targeting GM-CSF axis

The protein GM-CSF plays a critical role in maintaining immune tolerance in the gut, with defects in the protein increasing the susceptibility to inflammatory bowel diseases (IBD), according to a new mouse study by a team of researchers from the Icahn School of Medicine at Mount Sinai.

17 Mar 2014

Scientists discover gene variation that makes humans have healthier blood lipid levels, reduced risk of heart attacks

Scientists have discovered a previously unrecognized gene variation that makes humans have healthier blood lipid levels and reduced risk of heart attacks -- a finding that opens the door to using this knowledge in testing or treatment of high cholesterol and other lipid disorders.

17 Mar 2014

Professor wins Paul Ehrlich and Ludwig Darmstaedter Prize for research on immune system

Michael Reth has won the Paul Ehrlich and Ludwig Darmstaedter Prize, awarded by the Paul Ehrlich Foundation, for his research on the immune system. For the first time since 1996, the prize goes to a scientist working in Germany.

17 Mar 2014

UC Davis MIND Institute named Intellectual and Developmental Disabilities Research Center

The UC Davis MIND Institute has been named an Intellectual and Developmental Disabilities Research Center, through a prestigious grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health - a distinction held by only a handful of neurodevelopmental centers nationwide committed to the diagnosis, prevention, treatment and amelioration of developmental disorders such as autism, fragile X syndrome and Down syndrome.

14 Mar 2014

Study shows effect of oral fungal yeast in inhibiting thrush

Scientists at Case Western Reserve School of Medicine and University Hospitals (UH) Case Medical Center have discovered how the beneficial fungal yeast, Pichia, holds at bay a harmful fungal yeast, Candida.

14 Mar 2014

Researchers link heart attack and stroke biological events that lead to cardioprotection

Heart attack and stroke are among the most serious threats to health. But novel research at UT Southwestern Medical Center has linked two major biological processes that occur at the onset of these traumatic events and, ultimately, can lead to protection for the heart.

14 Mar 2014

Researchers Study how Marburg virus and host protein interaction help in developing inhibitors of virus

A protein that normally protects cells from environmental stresses has been shown to interact Marburg virus VP24, allowing the deadly Marburg virus to live longer and replicate better, according to a cell culture study led by scientists at the Icahn School of Medicine at Mount Sinai.

14 Mar 2014

Researcher detects higher rate of seizures among children with autism who were fed soy formula

A University of Wisconsin-Madison researcher has detected a higher rate of seizures among children with autism who were fed infant formula containing soy protein rather than milk protein.

14 Mar 2014

Study: Blocking body's immune response greatly reduces disability after stroke

A new study in animals shows that using a compound to block the body's immune response greatly reduces disability after a stroke.

14 Mar 2014

Researchers discover effective way of tuning muscle elasticity

How does yoga improve your flexibility? In the Mar 13 cover story of Cell, Columbia University biological sciences professor Julio Fernandez and team report the discovery of a new form of mechanical memory that adjusts the elasticity of muscles to their history of stretching.

14 Mar 2014

Researchers use computer-aided design tool to create genetic languages of biological systems

Researchers at Virginia Tech and the Massachusetts Institute of Technology have used a computer-aided design tool to create genetic languages to guide the design of biological systems.

14 Mar 2014

CNIO scientist wins 2014 Stewart Rahr-PCF Young Investigator Award from Prostate Cancer Foundation

David Olmos, the Spanish National Cancer Research Centre's Head of the Prostate Cancer and Genitourinary Tumours Clinical Research Unit, has won the 2014 Stewart Rahr-PCF Young Investigator Award, endowed by the Prostate Cancer Foundation - the leading philanthropic organisation for cutting-edge research into prostate cancer.

14 Mar 2014

Researchers find effective strategy to eliminate cancer stem-like cells

Combining nanodrug-based chemotherapy and cryoablation provides an effective strategy to eliminate cancer stem-like cells (CSCs) the root of cancer resistance and metastasis, which will help to improve the safety and efficacy of treating malignancies that are refractory to conventional therapies.

14 Mar 2014

A diet rich in animal protein may protect against age-related decline

Elderly individuals who consume higher levels of animal protein may be reducing their risk of physical, social and intellectual decline in the future, show study findings.

13 Mar 2014

Study: NGF-containing fibrin glue membrane can promote peripheral nerve regeneration

Complete regeneration is usually very difficult following peripheral nerve damage, though microsurgical techniques have vastly increased the success rate of surgery to repair the injured nerve.

13 Mar 2014

Study provides insight into the mechanisms underlying diabetic peripheral neuropathy

Iron overload can lead to cytotoxicity, and it is a risk factor for diabetic peripheral neuropathy. However, the underlying mechanism remains unclear.

13 Mar 2014

Researchers examine role of alpha-synuclein in neuronal cells

Alpha-synuclein is a principal component of Lewy bodies and Lewy neurites, which are pathologic hall-marks of Parkinson's disease. Alpha-synuclein is generally considered to play a role in synaptic activity, although its function remains largely unknown.

13 Mar 2014

Duke-NUS researchers shed light on process that inhibits tumor development

A team of researchers from Duke-NUS Graduate Medical School have discovered a protein complex that disrupts the process known as dedifferentiation, known to promote tumor development.

13 Mar 2014

Blocking function of enzyme slows spread of pancreatic cancer, say researchers

A research team from Imperial College London has shown that blocking the function of an enzyme known as Hhat slows the growth and spread of pancreatic cancer, by preventing a protein called Hedgehog from stimulating nearby normal cells to help the cancer.

13 Mar 2014

Protein C News and Research

Researchers identify novel protein that explains how biological clocks regulate human sleep

Study suggests effective therapeutics for IBD may hinge on targeting GM-CSF axis

Scientists discover gene variation that makes humans have healthier blood lipid levels, reduced risk of heart attacks

Professor wins Paul Ehrlich and Ludwig Darmstaedter Prize for research on immune system

UC Davis MIND Institute named Intellectual and Developmental Disabilities Research Center

Study shows effect of oral fungal yeast in inhibiting thrush

Researchers link heart attack and stroke biological events that lead to cardioprotection

Researchers Study how Marburg virus and host protein interaction help in developing inhibitors of virus

Researcher detects higher rate of seizures among children with autism who were fed soy formula

Study: Blocking body's immune response greatly reduces disability after stroke

Researchers discover effective way of tuning muscle elasticity

Researchers use computer-aided design tool to create genetic languages of biological systems

CNIO scientist wins 2014 Stewart Rahr-PCF Young Investigator Award from Prostate Cancer Foundation

Researchers find effective strategy to eliminate cancer stem-like cells

A diet rich in animal protein may protect against age-related decline

Study: NGF-containing fibrin glue membrane can promote peripheral nerve regeneration

Study provides insight into the mechanisms underlying diabetic peripheral neuropathy

Researchers examine role of alpha-synuclein in neuronal cells

Duke-NUS researchers shed light on process that inhibits tumor development

Blocking function of enzyme slows spread of pancreatic cancer, say researchers

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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