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Gene mutated in rare hereditary disorder also prevents mTORC1 pathway activation

Whitehead Institute scientists report that the gene mutated in the rare hereditary disorder known as Birt-Hogg-Dub- cancer syndrome also prevents activation of mTORC1, a critical nutrient-sensing and growth-regulating cellular pathway.

5 Nov 2013

Obese people experience substantial weight loss three years after bariatric surgery

In 3-year follow-up after bariatric surgery, substantial weight loss was observed among individuals who were severely obese, with most of the change occurring during the first year; however, there was variability in the amount of weight loss, as well as in diabetes, blood pressure, and lipid outcomes, according to a study published online by JAMA.

5 Nov 2013

Reviva announces successful completion of End-of-Phase 2 meeting for RP5063 drug

Reviva Pharmaceuticals, Inc., a privately held pharmaceutical company focused on the discovery and development of new, safer and highly effective therapies for chronic indications, announced today the successful completion of an End-of-Phase 2 meeting with the Food and Drug Administration for its lead, new investigational antipsychotic drug, RP5063.

5 Nov 2013

Researchers identify factor that promotes metastasis of colon tumors

Tumors become highly malignant when they acquire the ability to colonize other tissues and form metastases. Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have identified a factor that promotes metastasis of colon tumors - and presents a possible target for therapy.

5 Nov 2013

Computer-aided image analysis provides "second opinion" to identify breast tumor

Researchers at the University of Chicago are developing computer-aided diagnosis (CADx) and quantitative image analysis (QIA) methods for mammograms, ultrasounds and magnetic resonance images (MRIs) to identify specific tumor characteristics, including size, shape and sharpness, said lead researcher Maryellen Giger, A.N. Pritzker Professor of Radiology/Medical Physics and director of the Imaging Research Institute at the University of Chicago.

5 Nov 2013

Disruption of brain signals contributes to increased pain sensitivity in fibromyalgia patients

New research indicates that a disruption of brain signals for reward and punishment contributes to increased pain sensitivity, known as hyperalgesia, in fibromyalgia patients. Results published in Arthritis & Rheumatism, a journal of the American College of Rheumatology, suggest that this altered brain processing might contribute to widespread pain and lack of response to opioid therapy in patients with fibromyalgia.

5 Nov 2013

Children's Hospital to participate in drug study to evaluate effects of metformin for treating type 2 diabetes

Children's Hospital Los Angeles will participate in a nationwide drug study evaluating the effects of metformin, a medication that has been shown to be safe and effective for treating type 2 diabetes.

5 Nov 2013

Neurosurgeons use minimally-invasive technique to remove brain tumor

More than two decades ago, Ryan Vincent had open brain surgery to remove a malignant brain tumor, resulting in a lengthy hospital stay and weeks of recovery at home.

5 Nov 2013

The Princess Margaret Cancer Foundation launches innovative Fall advertising campaign

The Princess Margaret Cancer Foundation launches an innovative Fall advertising campaign this month which focuses on the extraordinary team of 63 surgeons, all of whom who are integral reasons why the Princess Margaret Cancer Centre is one of the top 5 cancer research centres in the world.

5 Nov 2013

Stem cell therapy after traumatic brain injury promotes lasting cognitive improvement

A stem cell therapy previously shown to reduce inflammation in the critical time window after traumatic brain injury also promotes lasting cognitive improvement, according to preclinical research led by Charles Cox, M.D., at The University of Texas Health Science Center at Houston (UTHealth) Medical School.

4 Nov 2013

Gene sequencing reveals mutations in estrogen receptor

Researchers at the University of Michigan Comprehensive Cancer Center have identified a type of mutation that develops after breast cancer patients take anti-estrogen therapies. The mutations explain one reason why patients often become resistant to this therapy.

4 Nov 2013

LMU researchers identify a factor that promotes metastasis of colon tumors

Tumors become highly malignant when they acquire the ability to colonize other tissues and form metastases. Researchers at Ludwig-Maximilians-Universitaet in Munich have identified a factor that promotes metastasis of colon tumors - and presents a possible target for therapy.

4 Nov 2013

RaySearch Laboratories, Hitachi sign long-term distribution agreement

RaySearch Laboratories AB has entered into a long-term distribution agreement with Hitachi Medical Corporation based in Tokyo, Japan. The agreement means that Hitachi will be fully responsible for marketing, sales and service of RaySearch's proprietary treatment planning system RayStation® on the Japanese market from April 1, 2014.

4 Nov 2013

Acoustic diode may improve future ultrasound images

Most people know about ultrasound through its role in prenatal imaging: those grainy, grey outlines of junior constructed from reflected sound waves. A new technology called an "acoustic diode," envisioned by researchers in China's Nanjing University, may dramatically improve future ultrasound images by changing the way sound waves are transmitted.

4 Nov 2013

Study in mice may help in the development of more effective treatments for anxiety disorders

Excessive fear can develop after a traumatic experience, leading to anxiety disorders such as post-traumatic stress disorder and phobias. During exposure therapy, an effective and common treatment for anxiety disorders, the patient confronts a fear or memory of a traumatic event in a safe environment, which leads to a gradual loss of fear.

4 Nov 2013

Heart failure patients may benefit from advanced treatment by heart specialists

New research from Karolinska Institutet in Sweden shows that patients with heart failure have high mortality and often are undertreated. According to a study, published in the scientific periodical JACC, many more of these patients would benefit from advanced treatment by heart specialists - something that could be decided by a simple evaluation of five common risk factors for early death due to heart failure.

4 Nov 2013

$IOF outlines guidelines to help prevent osteoporosis and fractures in cancer patients$

IOF outlines guidelines to help prevent osteoporosis and fractures in cancer patients

Cancer is a health burden of increasing importance which affects close to 13 million people globally. Bone is often affected in these patients, frequently because of bone metastases, or as a result of anti-cancer therapies which can contribute to bone loss and fragility.

4 Nov 2013

Discovery may lead to curing of Alzheimer's and Parkinson's disease via photo therapy

Researchers at Chalmers University of Technology in Sweden, together with researchers at the Polish Wroclaw University of Technology, have made a discovery that may lead to the curing of diseases such as Alzheimer's, Parkinson's and Creutzfeldt-Jakob disease (the so called mad cow disease) through photo therapy.

3 Nov 2013

Toxicity limits benefits of bevacizumab–erlotinib NSCLC maintenance therapy

Two targeted anticancer drugs used together after first-line chemotherapy for advanced stage non-small-cell lung cancer improve progression-free survival, the results of a large, prospective study show.

31 Oct 2013

New therapeutic approach for treating type 2 diabetes

Scientists from the Helmholtz Zentrum München (HMGU) and the Technische Universität München (TUM), together with scientists in the USA, have developed a new therapeutic approach for treatment of type 2 diabetes.

31 Oct 2013

Therapy News and Research

Gene mutated in rare hereditary disorder also prevents mTORC1 pathway activation

Obese people experience substantial weight loss three years after bariatric surgery

Reviva announces successful completion of End-of-Phase 2 meeting for RP5063 drug

Researchers identify factor that promotes metastasis of colon tumors

Computer-aided image analysis provides "second opinion" to identify breast tumor

Disruption of brain signals contributes to increased pain sensitivity in fibromyalgia patients

Children's Hospital to participate in drug study to evaluate effects of metformin for treating type 2 diabetes

Neurosurgeons use minimally-invasive technique to remove brain tumor

The Princess Margaret Cancer Foundation launches innovative Fall advertising campaign

Stem cell therapy after traumatic brain injury promotes lasting cognitive improvement

Gene sequencing reveals mutations in estrogen receptor

LMU researchers identify a factor that promotes metastasis of colon tumors

RaySearch Laboratories, Hitachi sign long-term distribution agreement

Acoustic diode may improve future ultrasound images

Study in mice may help in the development of more effective treatments for anxiety disorders

Heart failure patients may benefit from advanced treatment by heart specialists

IOF outlines guidelines to help prevent osteoporosis and fractures in cancer patients

Discovery may lead to curing of Alzheimer's and Parkinson's disease via photo therapy

Toxicity limits benefits of bevacizumab–erlotinib NSCLC maintenance therapy

New therapeutic approach for treating type 2 diabetes

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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