Cytoplasm News and Research

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Little-known protein found to play a role in common neurodegenerative disorder

Scientists have known for years that amyloid fibrils - fibrous, ropelike structures formed by closely linked protein molecules - are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

20 Apr 2022

The involvement of the skeletal muscles in long COVID-19

Researchers reviewed the mechanisms of muscle tissue injury, aggravating conditions, and associated sequelae in long COVID‐19.

18 Apr 2022

Role of cGAS-STING in SARS-CoV-2 infection

A new study analyzes the activation of cGAS and STING can induce a type I IFN response due to SARS-CoV-2 infection.

15 Apr 2022

Development of 18 monoclonal antibodies against 9 SARS-CoV-2 proteins

A new study aimed to generate, characterize, and optimize Abs against SARS-CoV-2 proteins.

12 Apr 2022

Scientists find critical role for Hippo signaling pathway in COVID-19 pathogenesis

A recent article posted to the bioRxiv* preprint server illustrated that the activation of the Hippo signaling pathway upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection aids the host antiviral response.

11 Apr 2022

Evidence of an increased risk of neurodegeneration after SARS-CoV-2 infection

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11 Apr 2022

Nanocell COVID-19 vaccine elicits potent neutralizing response

A new study describes the high level of neutralizing antibodies elicited by a nanocell vaccine against SARS-CoV-2 in vitro, in vivo, and human studies.

11 Apr 2022

Substantial SARS-CoV-2 infection in perivascular cells of inflamed blood vessels

A new study demonstrated that vascular inflammation leads to heightened SARS-CoV-2 infection in perivascular cells.

8 Apr 2022

Evidence SARS-CoV-2 undergoes ADAR-mediated A-to-I RNA editing in human cells

In a recent study published in the journal PLOS Genetics, researchers explored severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) ribonucleic acid (RNA) editing in host cells.

4 Apr 2022

Study analyzed several naturally-occurring amino acid variations found in the extended loop harboring the SARS-CoV-2 S1/S2 cleavage site

A recent study analyzed the polymorphisms in the SARS-CoV-2 spike proteins' S1/S2 subunits.

30 Mar 2022

Investigating SARS-CoV-2 detection using Raman microscopy

Researchers investigated the specific intracellular signature of SARS-CoV-2 infection using Raman microscopy.

29 Mar 2022

Chaperone-mediated autophagy needed to protect against atherosclerosis

Revving up a process that slows down as we age may protect against atherosclerosis, a major cause of heart attacks and strokes.

28 Mar 2022

How malaria drugs could play a part in treating chemotherapy-resistant head and neck cancers

In this interview, we speak to Kirill Kiselyov, Ph.D, and Umamaheswar Duvvuri, M.D, Ph.D, from the University of Pittsburgh, about their latest research into hydroxychloroquine, a drug widely used to prevent and treat malaria, as a potential treatment for head and neck cancers.

28 Mar 2022

Study explores macrophage susceptibility to SARS-CoV-2 virions

A new study investigated the susceptibility of macrophages to SARS-CoV-2 virions.

25 Mar 2022

People who consume sugar for extended periods have increased risk of autoimmune disease

People who consume sugar and other carbohydrates in excess over a long period of time have an increased risk of developing an autoimmune disease.

23 Mar 2022

New York Blood Center and Columbia University partner to advance the use of mRNA technology in HIV vaccine study

New York Blood Center’s Project ACHIEVE and Columbia University’s Columbia Research Unit are working in partnership for the New York City effort to advance the use of messenger ribonucleic acid (mRNA) technology in an HIV preventive vaccine study – HVTN 302.

23 Mar 2022

Cytoplasm News and Research

Little-known protein found to play a role in common neurodegenerative disorder

The involvement of the skeletal muscles in long COVID-19

Role of cGAS-STING in SARS-CoV-2 infection

Development of 18 monoclonal antibodies against 9 SARS-CoV-2 proteins

Scientists find critical role for Hippo signaling pathway in COVID-19 pathogenesis

Evidence of an increased risk of neurodegeneration after SARS-CoV-2 infection

Nanocell COVID-19 vaccine elicits potent neutralizing response

Substantial SARS-CoV-2 infection in perivascular cells of inflamed blood vessels

Evidence SARS-CoV-2 undergoes ADAR-mediated A-to-I RNA editing in human cells

Study analyzed several naturally-occurring amino acid variations found in the extended loop harboring the SARS-CoV-2 S1/S2 cleavage site

Investigating SARS-CoV-2 detection using Raman microscopy

Chaperone-mediated autophagy needed to protect against atherosclerosis

How malaria drugs could play a part in treating chemotherapy-resistant head and neck cancers

Study explores macrophage susceptibility to SARS-CoV-2 virions

People who consume sugar for extended periods have increased risk of autoimmune disease

New York Blood Center and Columbia University partner to advance the use of mRNA technology in HIV vaccine study

Function of glycolytic enzyme depends on its cellular localization

Study reveals how to identify and avoid risks related to mitochondrial therapeutic interventions

In silico screening and testing of FDA approved drugs inhibiting SARS-CoV-2 spike protein cleavage

Study shows SARS-CoV-2 infection induces global alterations of the host endomembrane system

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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