Malignant News and Research

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A-HIPI decision model can predict survival in adults with advanced-stage Hodgkin lymphoma

Investigators from Rutgers Cancer Institute of New Jersey, the state's only NCI-designated Comprehensive Cancer Center and leading cancer program along with Tufts Medical Center in Boston, developed and validated the Advanced-stage Hodgkin lymphoma International Prognostication Index (A-HIPI).

12 Dec 2022

Study may allow patients with multiple breast lesions to consider breast-conserving therapy as treatment option

Patients with multiple tumors in the same breast who underwent a lumpectomy followed by radiation therapy had local recurrence rates comparable to those historically observed in patients with a single tumor, according to results from the ACOSOG Z11102 (Alliance) prospective phase II clinical trial, which were presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

9 Dec 2022

Therapeutic activation of p53 could offer new treatment option for salivary gland cancer

Researchers at the University of Michigan Rogel Cancer Center and School of Dentistry found that certain drugs can change the fundamental makeup of cancer stem cells in mouse models of mucoepidermoid carcinoma – a lethal form of salivary gland cancer that currently has no treatment options.

8 Dec 2022

Research explores how alignment of endothelial cells plays a role in cancer metastasis

Preventing metastasis – the development of cancer cells beyond their original location – remains one of the major goals of current cancer research.

6 Dec 2022

The critical role of flow cytometry in CAR+ T-Cell trials

In this interview, Ryan Muise talks to AZoNetwork about the added value of using flow cytometry in CAR T-Cell clinical trials.

From Cerba Research 6 Dec 2022

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

Researchers evaluated blood plasma proteins to identify new targets for COVID-19 treatment approaches and prevent complications associated with severe illness.

5 Dec 2022

Researchers develop potent yet low-inflammatory mRNA cancer vaccine vectors

Lipid nanoparticle (LNP)-based messenger ribonucleic acid (mRNA) vaccines have recently emerged as a promising strategy for the prevention and treatment of cancers, as well as infectious diseases.

4 Dec 2022

The potential of grape consumption to modulate UV-induced skin erythema

A recent Antioxidants study evaluated the effect of grape consumption on reducing UV-induced skin erythema.

2 Dec 2022

The importance of early cancer screening

In this interview, Thomas Qiu, Senior Product Manager from BGI Genomics, talks to NewsMedical about current global cancer rates, and the importance of early cancer screening.

From BGI Genomics 1 Dec 2022

Human fetal cerebellar cell atlas reveals the origin of aggressive medulloblastomas

Studying mice has filled encyclopedias with breakthrough medical discoveries. But when it comes to brain cancers, the little rodents have long exhibited fundamental limitations.

30 Nov 2022

Stem cell crosstalk with the microenvironment creates a loop of tumor-promoting factors

What drives tumor growth? Is it a few rogue cells imposing their will upon healthy tissue, or diseased tissue bringing out the worst in otherwise peaceable cells? Or is it a back-and-forth, a dialogue between the two?

30 Nov 2022

Review: Phenotypes and origins of myeloid-derived suppressor cells

A new review was published in Oncotarget's Volume 13 on November 17, 2022, entitled, "Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more."

30 Nov 2022

New machine learning fusion model for better diagnosis of ovarian lesions

Although ovarian cancer is the deadliest type of cancer for women, only about 20% of cases are found at an early stage, as there are no real screening tests for them and few symptoms to prompt them.

29 Nov 2022

AI tool can reliably classify difficult-to-diagnose nasal cavity tumors

Although tumors in the nasal cavity and the paranasal sinus are confined to a small space, they encompass a very broad spectrum with many tumor types.

29 Nov 2022

Frequent surveillance imaging not linked to better outcomes following lung cancer surgery

Regular postsurgical screening is critical for patients with lung cancer, the United States' second most prevalent type of cancer and leading cause of cancer deaths.

28 Nov 2022

Researchers highlight the importance of localizing BRCA gene mutations for better ovarian cancer treatment

Mutations of BRCA1 and BRCA2 genes, which are inherited by 1 in 400 and 1 in 800 people respectively, significantly increase the risk of certain cancers such as ovarian, breast, pancreatic and prostate cancer.

28 Nov 2022

The potential for automatic diagnosis of palpable breast lumps without a radiologist or sonographer

A new study evaluated the efficacy of the volume sweep imaging ultrasound scans and artificial intelligence in providing fully automated and inexpensive breast ultrasound scans and interpretation without the need for experienced radiologists or sonographers.

28 Nov 2022

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

BGI has currently published over 440 SCI (Science Citation Index) papers in the field of cancer research, with a cumulative impact factor of over 4,000 points.

From BGI Genomics 23 Nov 2022

The role of bacteria in cancer growth

Tumor-associated microbiota is an important component of the tumor microenvironment (TME) across 33 types of human cancer. However, little evidence is available regarding the spatial distribution and localization of these microbes in tumor cells.

20 Nov 2022

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

A Ludwig Cancer Research study has revealed a single protein expressed at high levels by cancer cells across a broad range of malignancies that erects a multifaceted barrier to anti-cancer immune responses in mouse models of cancer and so shields tumors from immune detection and destruction.

20 Nov 2022

Malignant News and Research

A-HIPI decision model can predict survival in adults with advanced-stage Hodgkin lymphoma

Study may allow patients with multiple breast lesions to consider breast-conserving therapy as treatment option

Therapeutic activation of p53 could offer new treatment option for salivary gland cancer

Research explores how alignment of endothelial cells plays a role in cancer metastasis

The critical role of flow cytometry in CAR+ T-Cell trials

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

Researchers develop potent yet low-inflammatory mRNA cancer vaccine vectors

The potential of grape consumption to modulate UV-induced skin erythema

The importance of early cancer screening

Human fetal cerebellar cell atlas reveals the origin of aggressive medulloblastomas

Stem cell crosstalk with the microenvironment creates a loop of tumor-promoting factors

Review: Phenotypes and origins of myeloid-derived suppressor cells

New machine learning fusion model for better diagnosis of ovarian lesions

AI tool can reliably classify difficult-to-diagnose nasal cavity tumors

Frequent surveillance imaging not linked to better outcomes following lung cancer surgery

Researchers highlight the importance of localizing BRCA gene mutations for better ovarian cancer treatment

The potential for automatic diagnosis of palpable breast lumps without a radiologist or sonographer

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

The role of bacteria in cancer growth

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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