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Study reveals how medulloblastoma spreads and grows on the leptomeninges

Researchers at Baylor College of Medicine, Texas Children's Hospital, the Hospital for Sick Children in Toronto and collaborating institutions reveal in Nature Cell Biology a strategy that helps medulloblastoma, the most prevalent malignant brain tumor in children, spread and grow on the leptomeninges, the membranes surrounding the brain and spinal cord.

22 Apr 2025

DNA origami structures enable targeted imaging of pancreatic cancer

One of the challenges of fighting pancreatic cancer is finding ways to penetrate the organ's dense tissue to define the margins between malignant and normal tissue.

22 Apr 2025

Vitamin D curbs colorectal cancer by boosting immunity and blocking tumor growth

Review highlights how vitamin D, particularly its active form calcitriol, modulates immune responses, inflammation, and tumor progression to help prevent colorectal cancer (CRC). Evidence suggests adequate vitamin D levels and supplementation reduce CRC risk and improve outcomes.

21 Apr 2025

Differentiating cancerous and healthy cells through motion analysis

Researchers from Tokyo Metropolitan University have found that the motion of unlabeled cells can be used to tell whether they are cancerous or healthy.

20 Apr 2025

Unmasking Nrf2 as a key driver of treatment resistance in osteosarcoma

A deeper understanding of osteosarcoma, the most common primary malignant bone tumor affecting children and adolescents, is reshaping strategies for overcoming treatment resistance.

20 Apr 2025

Assessing the effectiveness of azvudine and paxlovid in hospitalized COVID-19 patients aged over 60

This new article publication from Acta Pharmaceutica Sinica B, discusses a retrospective cohort study of the efficacy and safety of oral azvudine versus nirmatrelvir/ritonavir in elderly hospitalized COVID-19 patients aged over 60 years.

14 Apr 2025

Understanding the complex spectrum of Castleman disease

Castleman disease (CD) is a rare, non-clonal lymphoproliferative disorder that manifests with a wide range of histologic and clinical features.

11 Apr 2025

New method uses sugar molecules to identify pancreatic cancer subtypes

Van Andel Institute scientists and collaborators have developed a new method for identifying and classifying pancreatic cancer cell subtypes based on sugars found on the outside of cancer cells.

9 Apr 2025

FGFR2 identified as key driver in KRAS-mutated pancreatic cancer progression

Precancerous pancreatic lesions and some pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS mutations had higher-than-normal expression of the FGFR2 protein, and FGFR2 inactivation delayed KRAS-mutated PDAC development in mice.

2 Apr 2025

AI-powered model improves prediction of bladder cancer treatment outcomes

Leveraging the power of AI and machine learning technologies, researchers at Weill Cornell Medicine developed a more effective model for predicting how patients with muscle-invasive bladder cancer will respond to chemotherapy.

28 Mar 2025

He had short-term health insurance. His colonoscopy bill: $7,000.

Tim Winard knew he needed to buy health insurance when he left his management job in manufacturing to launch his own business.

28 Mar 2025

Enhancing skin cancer screening with 3D imaging technology

The potential for 3D photography to improve melanoma early detection is a topic of increasing interest in the medical community.

27 Mar 2025

Study identifies PDGFRA as a potential target for pediatric high-grade gliomas

Pediatric high-grade gliomas, particularly H3K27M diffuse midline gliomas (DMG), are aggressive malignant brain tumors with a poor prognosis.

26 Mar 2025

City of Hope researchers uncover the two-step process of tumor formation

Researchers at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, have found that cell mutations are necessary but not always sufficient for tumors to form.

26 Mar 2025

Study explores the link between diet, blood glucose, and cancer risk

Researchers explore the relationship between diet, blood glucose levels, and cancer incidence across vertebrate species.

19 Mar 2025

In the Thymus We Trust: ProTcell Therapy & the Future of Allogeneic Immunotherapy

In this interview, News Medical speaks with Olivier Negre, Chief Scientific Officer at Smart Immune, about how immunotherapy is being revolutionized.

From Hanson Wade Group - 7th Allogeneic Cell Therapies Summit 18 Mar 2025

Pitt study uncovers a novel trigger of deadly form of ovarian cancer

Researchers at the University of Pittsburgh have identified a novel trigger of a deadly form of ovarian cancer: a subset of progenitor cells that reside in fallopian tube supportive tissue, or stroma.

14 Mar 2025

Special class of RNA molecules may provide a new target to treat gastric cancer

Researchers at Case Western Reserve University have discovered molecules that present the potential to drive the development of gastric cancer-among the world's deadliest forms of the disease.

13 Mar 2025

New technique effectively identifies aggressive medulloblastoma

Canadian researchers have developed an effective new technique for identifying aggressive medulloblastoma-the most common type of malignant brain tumour in children-and potentially sparing young patients from unnecessary treatments and their harmful long-term side effects.

12 Mar 2025

Study links Doomsday Clock to mortality and mental health

Since 1947, the Bulletin of the Atomic Scientists (BAS) has used the metaphor of the Doomsday Clock as a means of communicating how close the human species is to self-imposed annihilation, represented as midnight.

12 Mar 2025