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Sequenom CMM, CombiMatrix sign collaboration agreement to market CMA testing for NIPT

Sequenom, Inc., a life sciences company providing innovative diagnostic testing and genetic analysis solutions, and CombiMatrix Corporation, a molecular diagnostics laboratory performing DNA-based testing services for developmental disorders and cancer, today jointly announced that the Sequenom Center for Molecular Medicine LLC and CombiMatrix have entered into a collaboration agreement to market chromosomal microarray analysis testing services to broaden and confirm the results of noninvasive, prenatal testing to physicians and their patients.

1 Aug 2013

OGT to release new CytoSure Consortium Cancer +SNP array for CNV and LOH detection

Oxford Gene Technology (OGT), provider of innovative genetics research and biomarker solutions to advance molecular medicine, will launch its new CytoSure™ Consortium Cancer +SNP array (4x180k) at the Cancer Cytogenomics Microarray Consortium (CCMC) and Cytogenomics Array Group (CAGdb) combined meeting in Chicago on the 5th- 7th August, booth 4.

From Oxford Gene Technology 30 Jul 2013

Astrocytes can protect brain tissue and reduce disability due to stroke

One of regenerative medicine's greatest goals is to develop new treatments for stroke. So far, stem cell research for the disease has focused on developing therapeutic neurons - the primary movers of electrical impulses in the brain - to repair tissue damaged when oxygen to the brain is limited by a blood clot or break in a vessel. New UC Davis research, however, shows that other cells may be better suited for the task.

24 Jul 2013

Researchers distinguish viral and bacterial infections in children with fever

In children with fever but no other symptoms of illness, it is difficult to know whether a child has a viral infection that will resolve on its own or a potentially serious bacterial infection that requires antibiotics.

16 Jul 2013

Duke researchers solve some mysteries related to the use of aspirin

Aspirin has been widely used for more than 50 years as a common, inexpensive blood thinner for patients with heart disease and stroke, but doctors have little understanding of how it works and why some people benefit and others don't.

4 Jul 2013

Chromosomal deletion associated with changes in brain's white matter and delays language acquisition

A chromosomal deletion is associated with changes in the brain's white matter and delayed language acquisition in youngsters from Southeast Asia or with ancestral connections to the region, said an international consortium led by researchers at Baylor College of Medicine.

28 Jun 2013

Newly developed palm-sized microarray platform could enable faster, more efficient drug discovery

A new palm-sized microarray that holds 1,200 individual cultures of fungi or bacteria could enable faster, more efficient drug discovery, according to a study published in mBio-, the online open-access journal of the American Society for Microbiology.

25 Jun 2013

UT candidate wins AHA fellowship to support research in cardiovascular, stroke discoveries

University of Texas at San Antonio biomedical engineering Ph.D. candidate Anand Srinivasan has been awarded a $25,000, one-year doctoral fellowship from the American Heart Association (AHA).

20 Jun 2013

Genomic instability in new molecular pathway may predict worse outcomes in breast cancer patients

A new molecular pathway involving the gene ZNF365 has been identified and abnormalities in that pathway may predict worse outcomes for patients with breast cancer, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

18 Jun 2013

New technique offers potential to screen patients for viruses

In research published in Biochemical and Biophysical Research Communications, Saint Louis University researchers describe a technology that can detect new, previously unknown viruses. The technique offers the potential to screen patients for viruses even when doctors have not identified a particular virus as the likely source of an infection.

18 Jun 2013

Abnormal metabolic pathway drives cancer-cell growth in glioblastoma subtype

A study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) has identified an abnormal metabolic pathway that drives cancer-cell growth in a particular glioblastoma subtype. The finding might lead to new therapies for a subset of patients with glioblastoma, the most common and lethal form of brain cancer.

14 Jun 2013

Prostate cancer and DNA: an interview with Dr. Jianfeng Xu, Wake Forest School of Medicine

Prostate cancer development is associated with both inherited and acquired genetic alterations. More than 70 inherited genetic variants have been consistently identified in human DNA that may contribute to susceptibility or risk of prostate cancer.

11 Jun 2013

New non-invasive test measures methylation of SDC2 gene, detects 87% of colorectal cancer

The average 5-year survival for colorectal cancer (CRC) is less than 10% if metastasis occurs, but can reach 90% if detected early. A new non-invasive test has been developed that measures methylation of the SDC2 gene in tissues and blood sera.

10 Jun 2013

Study: Individuals with ASDs show decrease metabolism of amino acid L-tryptophan

Researchers at the JC Self Research Institute of the Greenwood Genetic Center (GGC), along with collaborators from Biolog, Inc. in California, have reported an important discovery in the understanding of autism which was published this week in Molecular Autism.

7 Jun 2013

New study reveals another duet played by Notch and BMP signals

A small ensemble of musicians can produce an infinite number of melodies, harmonies and rhythms. So too, do a handful of workhorse signaling pathways that interact to construct multiple structures that comprise the vertebrate body.

15 May 2013

Idera to present data from Phase 2 trial of IMO-3100 in patients with psoriasis at IID 2013

Idera Pharmaceuticals today announced presentation of data from its randomized, double-blind, placebo-controlled Phase 2 trial that showed improvements from baseline of up to 90% in Psoriasis Area Severity Index scores in patients with moderate to severe plaque psoriasis following four weeks of treatment with the Toll-like Receptor antagonist IMO-3100.

8 May 2013

Measurement variation influences gene expression profiles of breast cancer

An important new study has revealed the clearest picture yet of precisely how much measurement variation influences gene expression profiles of breast cancer.

3 May 2013

Cancer Genetics introduces proprietary urogenital cancer array for diagnosing kidney cancer

Cancer Genetics, Inc., a leader in oncology-focused personalized medicine, has launched a proprietary urogenital cancer array, UroGenRA, intended for kidney cancer diagnosis and subtyping in its own laboratory.

3 May 2013

EventusDx receives CE mark designation for Octava Pink breast cancer test

Eventus Diagnostics, Inc. today announced that it has received CE mark designation for its Octava Pink™ breast cancer test intended for confirmatory use in women who have received negative mammography results.

2 May 2013

Research shows how pregnancy lowers risk of breast cancer

Being pregnant while young is known to protect a women against breast cancer. But why? Research in BioMed Central's open access journal Breast Cancer Research finds that Wnt/Notch signalling ratio is decreased in the breast tissue of mice which have given birth, compared to virgin mice of the same age.

29 Apr 2013