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New treatment boosts pluripotent stem cell production in mice

Researchers at the Centre for Genomic Regulation (CRG) have discovered a treatment which accelerates the production and quality of pluripotent stem cells in mice.

7 Aug 2024

Decoding glioblastoma: New insights into molecular subtypes and mesenchymal transition mechanisms

Glioblastoma multiforme (GBM) stands as a formidable adversary in oncology, characterized by its molecular complexity and relentless progression.

7 Aug 2024

Understanding the age gap in leukemia survival rates

Acute lymphoblastic leukemia (ALL) affects both children and adults, but children have better chances to be cured, with long-term survival rates over 85% compared to 50-75% in adults. Scientists at St. Jude Children's Research Hospital conducted a comprehensive study to understand the biological causes driving this difference. The work, published today in the Journal of Clinical Oncology, provides a blueprint for understanding B-cell acute lymphoblastic leukemia (B-ALL), the most common form of the disease.

7 Aug 2024

Advancing risk stratification for DSP cardiomyopathy with postmortem genetic testing

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Both DSP cardiomyopathy and plakophilin 2 are associated with arrhythmogenic right ventricular cardiomyopathies via a desmosomal mechanism.

6 Aug 2024

UVA professor wins NIH Maximizing Investigator's Research Award for breakthrough biomedicine research

University of Virginia assistant engineering professor Liheng Cai has earned the Maximizing Investigator's Research Award from the National Institutes of Health.

5 Aug 2024

New frontiers in organ regeneration with 3D bioprinting

In a latest review published in Engineering, an international team of scientists from China and the United States has presented a comprehensive analysis of the latest advancements in 3D organ bioprinting. This innovative technology holds the potential to revolutionize regenerative medicine and tackle some of the most pressing issues in organ transplantation.

2 Aug 2024

Innovative tissue slicing method for improved clinical outcomes

In a pioneering development for the biomedical field, a research team led by Yuanjin Zhao from Nanjing Drum Tower Hospital, China, has published a research article in Engineering. The article, titled "Controllable Histotomy Based on Hierarchical Magnetic Microneedle Array Robots," introduces a novel technique for tissue slicing and cultivation that could revolutionize the way primary tissues are handled in clinical settings.

30 Jul 2024

New guidelines expand BRCA testing and screening for men

More and more studies show that men face risks of cancer from BRCA1 and BRCA2 genetic mutations that are most often associated with breast and ovarian cancers in women.

27 Jul 2024

Insilico Medicine's PandaOmics Box enhances drug discovery with advanced AI capabilities

The development of innovative medicines is an expensive, time-consuming and risky business. On average, it usually takes at least a decade and billions of dollars to bring a new drug from project initiation to approval.

25 Jul 2024

Gene variant predicts cognitive decline after stroke

New research led by UCLA Health has found that specific genes may be related to the trajectory of recovery for stroke survivors, providing doctors insights useful for developing targeted therapies.

25 Jul 2024

Understanding Consumer-Consented Data to Optimize Clinical Trials and Digital Health Programs

In this interview, News Medical speaks with the Healthcare Business of LexisNexis® Risk Solutions about optimizing clinical trial screening and digital health programs through a better understanding of consumer-consented data.

From LexisNexis® Risk Solutions 22 Jul 2024

Elite Controllers: Do their genomes hold the key to curing HIV?

Although South Africa has the largest number of people living with HIV worldwide, strides have been made in controlling the epidemic, especially in the reduction of HIV incidence, testing, and treatment. Equipped with MGI’s advanced sequencing tools and technologies, researchers from the South African Medical Research Council (SAMRC) and University of KwaZulu-Natal (UKZN) are inching closer to finding the answer to the natural control of HIV infection, leading to improved health outcomes and quality of life amongst South Africans.

From MGI 19 Jul 2024

Accelerate Your Research: Dispen3D Harnesses the Power of 3D Models

Dispen3D is setting new standards in single-cell biology, enabling researchers to conduct high-precision experiments that drive advancements in drug discovery, personalized medicine, and regenerative therapies.

From SEED Biosciences 12 Jul 2024

Protein nanocages: A promising frontier in mRNA therapeutics

In recent years, messenger RNA (mRNA) has emerged as a promising avenue for accurate and potent therapeutic interventions. Unlike DNA drugs, mRNA can express genetic information without the risk of integrating into the host genome.

3 Jul 2024

New techniques revolutionize muscle strength assessment

Understanding individual muscle strength is crucial for optimizing physical therapy and enhancing athletic performance. Traditional methods, however, often fall short in precision. The newly introduced technique by Zuming Xiao and colleagues from the Beijing Institute of Technology and Shenyang Sport University bridges this gap by integrating direct muscle strength measurements with dynamic simulations.

28 Jun 2024

A unifying marker streamlines macrophage research across age and sex

Macrophages play a critical role in the immune system by fighting infections and aiding in tissue repair. Understanding how these cells are activated in different scenarios is important for developing new medical treatments. However, identifying and studying macrophage activation has been challenging due to the complex nature of these cells and their responses.

27 Jun 2024

CSF1R marker enables study of Macrophage Activation Mosaicism

Macrophages play a critical role in the immune system by fighting infections and aiding in tissue repair.

26 Jun 2024

Liquid core fibers offer long-term drug delivery in medical textiles

Treating a wound or an inflammation directly where it occurs has clear advantages: The active ingredient reaches its target immediately, and there are no negative side effects on uninvolved parts of the body.

26 Jun 2024

New insights into signaling pathways and resistance mechanisms in colorectal cancer

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. The complexity of its pathogenesis, involving genetic mutations, dysregulated signaling pathways, and compromised immune surveillance, presents significant challenges for effective treatment.

21 Jun 2024

Laser-based 3D bioprinting of corneas for vision restoration

Printing a new cornea during an operation to restore a patient's eyesight: This groundbreaking step in the fight against corneal disorders is set to become reality with a laser based process using personalized bioink.

19 Jun 2024