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Study reveals conserved and divergent host responses to infections with SARS-CoV-2 variants of concern

Researchers analyzed the phenotypes of the SARS-CoV-2 variants of concern (VOCs), the molecular responses to infections from these VOCs, and the evolving virus-host interactions using a comparative genomic and proteomic approach.

26 Oct 2022

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

In a recent study posted to the bioRxiv* server, researchers in the United States demonstrated how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame 6 (ORF6) protein contributes to viral pathogenesis and modulates the host's immune responses.

23 Oct 2022

Review on Panax ginseng therapeutic efficacy for COVID-19-associated neurological diseases

In a new study, researchers discussed the therapeutic potential of Panax ginseng for COVID-19 (coronavirus disease 2019)-induced neurological diseases.

14 Oct 2022

Multiomic comparison shows a reduction in circulating monocytes correlated with persistent post-COVID-19 pulmonary fibrosis

In a new study, researchers identified distinguishing immune features of coronavirus disease 2019 (COVID-19) in patients with late-resolving pulmonary fibrosis (LR COVID-PF) and early-resolving (ER COVID-PF).

4 Oct 2022

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

Researchers explored the in vivo efficacy of SARS-CoV-2-encoded proteins against neuromuscular degeneration associated with ribosome stalling.

3 Oct 2022

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Researchers discuss a robust method to identify mutations that improve the expression and stabilize the conformation of the SARS-CoV-2 spike protein.

29 Sep 2022

What is the impact of SARS-CoV-2 infection on semen parameters and sex hormones?

A new study aimed to systematically review studies investigating sex hormones and semen parameters in COVID-19 patients to provide a better understanding and treatment approach.

27 Sep 2022

LncDACH1 may be a potential therapeutic target for pulmonary fibrosis

This new article publication from Acta Pharmaceutica Sinica B, discusses how LncRNA DACH1 protects against pulmonary fibrosis by binding to SRSF1 to suppress CTNNB1 accumulation.

26 Sep 2022

Exercise hormone irisin blocks Parkinson's-associated α-synuclein aggregation and related neuronal toxicity

A new paper discusses the hope held out by recent results on a compound called irisin, a short protein secreted by skeletal muscle that produces some exercise-related effects on the brain.

15 Sep 2022

COVID-19's future is uncertain as infections increase and tracking decreases

Researchers review how the SARS-CoV-2 genome has changed throughout the COVID-19 pandemic.

14 Sep 2022

What is the impact of COVID-19 treatments targeting intracellular Neu1?

In a new study, researchers assessed the impact of targeting intracellular Neu1 on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

14 Sep 2022

Signal transduction via the EGFR pathway likely to be involved in lenvatinib resistance

The multitargeted tyrosine kinase inhibitor (MKI), lenvatinib, is widely used to treat advanced and metastatic thyroid cancer. However, the molecular mechanisms by which thyroid cancer cells become resistant to lenvatinib remain poorly understood. In this study, we demonstrated, for the first time, that activation of the epidermal growth factor receptor (EGFR)-mediated signaling pathway is involved in lenvatinib resistance in thyroid cancer cells.

14 Sep 2022

Photocatalyst-based ViraMap platform maps SARS-CoV-2 spike protein interactions on the cell surface

Researchers performed the photocatalytic mapping of the SARS-CoV-2 spike protein-host cell membrane interactions.

7 Sep 2022

Novel mechanism identified that SARS-CoV-2 uses to suppress antiviral responses to make the cell more permissive to infection

Researchers assessed the impact of SARS-CoV-2 ORF-6 on innate immune signaling.

30 Aug 2022

Protein Expression News and Research

Study reveals conserved and divergent host responses to infections with SARS-CoV-2 variants of concern

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

Review on Panax ginseng therapeutic efficacy for COVID-19-associated neurological diseases

Multiomic comparison shows a reduction in circulating monocytes correlated with persistent post-COVID-19 pulmonary fibrosis

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

What is the impact of SARS-CoV-2 infection on semen parameters and sex hormones?

LncDACH1 may be a potential therapeutic target for pulmonary fibrosis

Exercise hormone irisin blocks Parkinson's-associated α-synuclein aggregation and related neuronal toxicity

COVID-19's future is uncertain as infections increase and tracking decreases

What is the impact of COVID-19 treatments targeting intracellular Neu1?

Signal transduction via the EGFR pathway likely to be involved in lenvatinib resistance

Photocatalyst-based ViraMap platform maps SARS-CoV-2 spike protein interactions on the cell surface

Novel mechanism identified that SARS-CoV-2 uses to suppress antiviral responses to make the cell more permissive to infection

New study provides comparison of replicating and non-replicating vaccines against SARS-CoV-2

Non-invasive biomarker could aid with earlier diagnosis of breast cancer metastasis

Insights into the products and services of Azenta

Researchers delve deeper into the structure of protein receptor crucial for cardiovascular health

Scientists develop a novel, highly-efficient sample preparation method for single-cell proteomics

A combined influenza and COVID-19 mRNA vaccine

Industry Focus eBook - Protein Analysis (3rd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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