p53 Protein News and Research

RSS

The TP53 is a gene that instructs the cell to produce tumor protein (p53) ; a vital transcription factor and tumor suppressor. P53 is known as the “guardian of the genome” as it helps in regulating the cell cycle and acts as a tumor suppressor.

New compound, ZK-CDK combines the inhibition of tumour cell growth as well as inhibition of tumour angiogenesis in one single molecule

Treatment with a new dual cell cycle and angiogenesis pathway inhibitor blocks VEGF-induced vascular permeability, inhibits tumour angiogenesis and induces apoptosis in human tumour models

7 Jul 2004

African-American women less likely to survive breast cancer than white women

A new study led by investigators at Fred Hutchinson Cancer Research Center may help explain why African-American women with breast cancer are more likely to be diagnosed with advanced disease and are less likely to survive the disease than white women.

15 Jun 2004

New way by which cells can become cancerous may solve mystery with lung cancer

Researchers at The University of Texas M. D. Anderson Cancer Center are describing an entirely new way by which cells can become cancerous. And they say their finding provides an answer to a mystery in lung and other cancers.

8 May 2004

Researchers find an entirely new way by which cells can become cancerous

Finding provides an answer to a mystery in lung and other cancers: why a potent tumor suppressor gene called FUS1 functions as it should, yet none of the protein it produces can be found anywhere in a cancer cell.

6 May 2004

World's first gene therapy trial aimed at preventing cancer

The concept seems straightforward. If, at its heart, cancer is a disease of genes, then giving patients new genes should disarm cancer. Such treatment would replace missing or faulty genes that keep cell growth in check, or would flush the body with "super genes" that could attack and destroy cancer.

5 May 2004

UK scientists have discovered cancer cells life and death scenario following anti-cancer treatment

CANCER Research UK scientists have discovered how some cancer cells choose to live and others die following anti-cancer treatment, unveiling their findings in the prestigious journal PNAS today.

26 Apr 2004

p53 protein peptide stops cancer in its tracks

Researchers have dreamed of thwarting cancer by using proteins that halt cell growth and kill the tumor. In theory, the approach should work. In practice, however, scientists have not had an easy time of getting tumor suppressor proteins into cells where they can block growth effectively.

26 Mar 2004