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Study clarifies the effect of aging on hematopoietic stem cells

By transferring mouse aged hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was demonstrated that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic stem cells.

24 Dec 2020

Researcher discovers seven DNA fingerprints that define cancer risk

Lifestyle, or put another way 'bad habits', is one of the textbook explanations for why some people are at higher risk for cancer.

23 Dec 2020

New results challenge prevailing dogma regarding brain plasticity following limb loss

Advances in neuroscience and engineering have generated great hope for Luke Skywalker-like prosthetics: robotic devices that are almost indistinguishable from a human limb.

23 Dec 2020

Modulating BST2 expression on blood stem cells may help regulate cell activation during chronic infections

When a person has an infection, the body activates immune responses to fight it. IFNγ is an inflammatory molecule produced by the immune system that helps fight infections.

23 Dec 2020

Researchers use massive sequencing methods to identify rare genetic bone disorder

Researchers of the "Cell Biology and Physiology-LABRET" group of the University of Malaga (UMA), together with the Networking Biomedical Research Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), have described a new genetic skeletal disorder based on a precision medicine strategy.

22 Dec 2020

Researchers establish BRIDGES program to synergize diagnostic efforts, patient outcome management

For over 20 years, the Genetics Service at the KK Women's and Children's Hospital (KKH) has been providing clinical care to patients with genetic disorders.

22 Dec 2020

Researchers use precision medicine strategy to identify a new genetic skeletal disorder

21 Dec 2020

South Korean city shows SARS-CoV-2 clade shift from V to GH over time

A new paper from South Korea describes the evolving SARS-CoV-2 genome in a single city, that of Gwangju, in the southwestern region of this country.

21 Dec 2020

Researchers find the "true" rate of dislocation following total hip replacement

The cumulative incidence of hip dislocation following total hip replacement is about 50 percent higher than suggested by simple analysis of hospital data, reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.

21 Dec 2020

New understanding of physical properties of chromatin may show how genome is encoded and decoded

University of Alberta researchers have found an answer to a fundamental question in genomic biology that has eluded scientists since the discovery of DNA: Within the nucleus of our cells, is the complex package of DNA and proteins called chromatin a solid or a liquid?

20 Dec 2020

FDA approves first implant system for adults who have above-the-knee amputations

The U.S. Food and Drug Administration today approved the Osseoanchored Prostheses for the Rehabilitation of Amputees (OPRA) Implant System, the first implant system marketed in the U.S. for adults who have transfemoral—or above-the-knee—amputations and who have or are anticipated to have rehabilitation problems with, or cannot use, a conventional socket prosthesis.

18 Dec 2020

Landmark study finds how often cancer patients develop osteonecrosis of the jaw

A landmark study by researchers from the SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute, part of the National Institutes of Health, has found that 2.8 percent of patients on average develop osteonecrosis of the jaw, or ONJ, within three years of starting a common treatment for cancer that has spread to the bone.

17 Dec 2020

Study shows benefits of integrated palliative and oncology care for patients with advanced AML

A first-of-its-kind intervention integrating palliative care early in the course of cancer therapy for patients with advanced acute myeloid leukemia (AML), a highly aggressive cancer of the blood and bone marrow, resulted in substantial improvements in patients' quality of life, mood and end-of-life care, a team of investigators has found.

17 Dec 2020

Scientists demonstrate a promising strategy for treating lymphomas

Scientists at Scripps Research have demonstrated a promising new strategy for treating lymphomas, a group of cancers that begin in infection-fighting cells of the immune system called lymphocytes.

16 Dec 2020

Study shows highest risk of vitamin D deficiency in BAME babies

A third of all babies and half of Black, Asian and Minority Ethnic (BAME) babies are vitamin D deficient, a large study of 3000 newborn's in the West Midlands has shown, highlighting potential shortfalls in the current UK antenatal supplementation program.

16 Dec 2020

FDA grants marketing authorization for new ACL implant

Today, the U.S. Food and Drug Administration granted marketing authorization—under the De Novo premarket review pathway—for an anterior cruciate ligament (ACL) implant, intended to serve as an alternative to ACL reconstruction to treat ACL tears.

16 Dec 2020

Regulatory policies block transgender and gender diverse individuals from accessing care

The Endocrine Society and the Pediatric Endocrine Society oppose legislative efforts to block transgender and gender diverse individuals from accessing gender-affirming medical and surgical care, the two medical societies said in a joint policy perspective published in The Journal of Clinical Endocrinology & Metabolism.

16 Dec 2020

Bone News and Research

Study clarifies the effect of aging on hematopoietic stem cells

Researcher discovers seven DNA fingerprints that define cancer risk

New results challenge prevailing dogma regarding brain plasticity following limb loss

Modulating BST2 expression on blood stem cells may help regulate cell activation during chronic infections

Researchers use massive sequencing methods to identify rare genetic bone disorder

Researchers establish BRIDGES program to synergize diagnostic efforts, patient outcome management

Researchers use precision medicine strategy to identify a new genetic skeletal disorder

South Korean city shows SARS-CoV-2 clade shift from V to GH over time

Researchers find the "true" rate of dislocation following total hip replacement

New understanding of physical properties of chromatin may show how genome is encoded and decoded

FDA approves first implant system for adults who have above-the-knee amputations

Landmark study finds how often cancer patients develop osteonecrosis of the jaw

Study shows benefits of integrated palliative and oncology care for patients with advanced AML

Scientists demonstrate a promising strategy for treating lymphomas

Study shows highest risk of vitamin D deficiency in BAME babies

FDA grants marketing authorization for new ACL implant

Regulatory policies block transgender and gender diverse individuals from accessing care

Novel MRI contrast agent shows strong potential as safer alternative to current products

New class of targeted cancer drugs may prove effective in treating common types of leukemia

Abnormalities in bone microarchitecture linked to risk of complications after spinal fusion surgery

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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