Central Nervous System News and Research

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Preclinical study reveals pomalidomide shows promising results for treatment of CNS lymphoma

A drug recently approved for use in multiple myeloma is now being tested for its ability to fight central nervous system (CNS) lymphoma, a deadly cancer of the immune system that can affect the brain, spinal cord and fluid, and eyes.

13 Aug 2013

Cedars-Sinai launches Phase I clinical trial to study tolerability of immunization to treat Alzheimer's disease

Cedars-Sinai Medical Center has launched a Phase I clinical trial to study the safety and tolerability of an experimental immunization to treat Alzheimer's disease. The treatment is based on Copaxone (glatiramer acetate), a drug often prescribed to reduce the frequency of multiple sclerosis relapses.

13 Aug 2013

Omeros announces financial results for second quarter of 2013

Omeros Corporation, a clinical-stage biopharmaceutical company committed to discovering, developing and commercializing products targeting inflammation, coagulopathies and disorders of the central nervous system, today announced its financial results for the second quarter of 2013.

12 Aug 2013

Drug-related emergency department visits increase among younger adults

A new report by the Substance Abuse and Mental Health Services Administration shows that some drug-related emergency department visits increased by 300 percent -- from 5,605 visits in 2005 to 22,949 visits in 2011. These visits, made by adults aged 18 to 34, were related to the nonmedical use of central nervous system stimulants. On average, about 30 percent of these visits also involved alcohol.

9 Aug 2013

Harmful toxins found in food may put developing babies at risk

Pregnant women regularly consume food and beverages containing toxins believed to pose potential risks to developing fetuses, according to researchers at the University of California in Riverside and San Diego, suggesting that health care providers must do more to counsel their patients about the dangers of hidden toxins in the food supply.

8 Aug 2013

Research suggests treadmill training after spinal cord injury can have positive effects on recovery

New research suggests that treadmill training soon after a spinal cord injury can have long-lasting positive effects on recovery - as long as the training is accompanied by efforts to control inflammation in the lower spinal cord.

8 Aug 2013

SmartTots announces recipients of pediatric anesthesia research grants

SmartTots announces Lena Sun, MD and Jeffrey William Sall, PhD, MD as the recipients of its 2013/2014 round of pediatric anesthesia research grants. The research grants are intended to support investigations into the existence of a clinical signal suggesting poor neurocognitive outcomes as the result of early exposure to anesthesia.

7 Aug 2013

Sensor-based motion tracking system can be used to evaluate neurorehabilitation of upper limbs

Upper limb function impairment is one of the most common sequelae of central nervous system injury. Conventional assessment methods cannot provide objective evaluation of patient performance and the effectiveness of therapies.

6 Aug 2013

Transmembrane protein NG2 controls orientation of cell migration toward the wound

When the central nervous system is injured, oligodendrocyte precursor cells migrate to the lesion and synthesize new myelin sheaths on demyelinated axons. Scientists at the Institute of Molecular Cell Biology at Johannes Gutenberg University Mainz have now discovered that a distinct protein regulates the direction and movement of OPC toward the wound. The transmembrane protein NG2, which is expressed at the surface of OPCs and down-regulated as they mature to myelinating oligodendrocytes, plays an important role in the reaction of OPC to wounding.

1 Aug 2013

Naurex receives new U.S. patent for its lead compound, GLYX-13

Naurex Inc., a clinical-stage company developing innovative treatments to address unmet needs in psychiatry and neurology, today announced issuance of a new U.S. patent for its lead compound, GLYX-13.

31 Jul 2013

Research finds that aging elicits changes in taste preferences

Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, found that aging elicits changes in taste preferences and that such changes appear to be independent of taste nerve activity.

31 Jul 2013

METH use can make person more susceptible to fungal lung infection

Methamphetamine use can make a person more susceptible to the lung infection cryptococcosis, according to a study published in mBio-, the online open-access journal of the American Society for Microbiology.

30 Jul 2013

FDA grants orphan-drug designation to Convergence's CNV1014802 for treatment of TN

Convergence Pharmaceuticals Limited, the company focused on the development of novel and high value analgesic medicines for the treatment of chronic pain, is pleased to announce that its novel sodium channel blocker, CNV1014802 ('802), has been granted orphan-drug designation by the US Food and Drug Administration for the treatment of trigeminal neuralgia.

30 Jul 2013

Emergency physicians correctly identify nearly 100% of patients with Bell's palsy

Emergency physicians correctly identified nearly 100 percent of patients with Bell's palsy, the symptoms of which are nearly identical to potentially life-threatening diseases such as stroke and brain tumors.

26 Jul 2013

AANS, CNS commend House committee efforts to repeal Medicare's flawed SGR payment formula

The American Association of Neurological Surgeons and Congress of Neurological Surgeons joined 11 other medical societies in commending the U.S. House Energy and Commerce Committee for its bipartisan efforts to repeal and replace Medicare's flawed sustainable growth rate payment formula.

24 Jul 2013

Researchers develop reliable way to use finger-stick blood sample to detect fibromyalgia syndrome

Researchers have developed a reliable way to use a finger-stick blood sample to detect fibromyalgia syndrome, a complicated pain disorder that often is difficult to diagnose.

24 Jul 2013

Digital versions of standard molecular biology tool to detect common tumor-associated mutation in CSF

Massachusetts General Hospital (MGH) researchers and their colleagues have used digital versions of a standard molecular biology tool to detect a common tumor-associated mutation in the cerebrospinal fluid (CSF) of patients with brain tumors. In their report being published in the open-access journal Molecular Therapy - Nucleic Acids, the investigators describe using advanced forms of the gene-amplification technology polymerase chain reaction (PCR) to analyze bits of RNA carried in membrane-covered sacs called extracellular vesicles for the presence of a tumor-associated mutation in a gene called IDH1.

24 Jul 2013

Researchers develop microbial washing technique to decontaminate fetal tissues

The use of central nervous system fetal tissues derived from routine elective abortions to provide stem cells for transplantation procedures aimed at restoring damage done by neurodegenerative diseases is an established therapy.

23 Jul 2013

Findings show oxytocin strengthens bad memories and increases fear, anxiety

It turns out the love hormone oxytocin is two-faced. Oxytocin has long been known as the warm, fuzzy hormone that promotes feelings of love, social bonding and well-being. It's even being tested as an anti-anxiety drug. But new Northwestern Medicine- research shows oxytocin also can cause emotional pain, an entirely new, darker identity for the hormone.

23 Jul 2013

Quickly clearing out damaged proteins may help prevent neurodegenerative disorders: Study

Recycling is not only good for the environment, it's good for the brain. A study using rat cells indicates that quickly clearing out defective proteins in the brain may prevent loss of brain cells.

22 Jul 2013

Central Nervous System News and Research

Preclinical study reveals pomalidomide shows promising results for treatment of CNS lymphoma

Cedars-Sinai launches Phase I clinical trial to study tolerability of immunization to treat Alzheimer's disease

Omeros announces financial results for second quarter of 2013

Drug-related emergency department visits increase among younger adults

Harmful toxins found in food may put developing babies at risk

Research suggests treadmill training after spinal cord injury can have positive effects on recovery

SmartTots announces recipients of pediatric anesthesia research grants

Sensor-based motion tracking system can be used to evaluate neurorehabilitation of upper limbs

Transmembrane protein NG2 controls orientation of cell migration toward the wound

Naurex receives new U.S. patent for its lead compound, GLYX-13

Research finds that aging elicits changes in taste preferences

METH use can make person more susceptible to fungal lung infection

FDA grants orphan-drug designation to Convergence's CNV1014802 for treatment of TN

Emergency physicians correctly identify nearly 100% of patients with Bell's palsy

AANS, CNS commend House committee efforts to repeal Medicare's flawed SGR payment formula

Researchers develop reliable way to use finger-stick blood sample to detect fibromyalgia syndrome

Digital versions of standard molecular biology tool to detect common tumor-associated mutation in CSF

Researchers develop microbial washing technique to decontaminate fetal tissues

Findings show oxytocin strengthens bad memories and increases fear, anxiety

Quickly clearing out damaged proteins may help prevent neurodegenerative disorders: Study

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