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Autism treatment: Social impairments can be corrected by brain stimulation

Scientists are examining the feasibility of treating autistic children with neuromodulation after a new study showed social impairments can be corrected by brain stimulation.

13 Dec 2017

Researchers suggest role for MKL1 protein in development of inflammatory bowel disease

Inflammatory bowel disease (IBD), including the two conditions ulcerative colitis and Crohn's disease, results in long-term inflammation of the gut and is associated with dysregulation of the immune system.

13 Dec 2017

Cellular self-digestion process plays role in development of autoimmune diseases

Autophagy allows cells to degrade and recycle their cellular components. Researchers at UZH have now demonstrated that the autophagy machinery in certain immune cells leads to the immune system attacking the central nervous system.

13 Dec 2017

UQ researchers create new and improved version of ‘love hormone’

A new and improved version of the ‘love hormone’ oxytocin has been developed by University of Queensland researchers.

13 Dec 2017

Canola oil linked to worsening of Alzheimer’s

Canola oil has been marketed as a healthy cooking oil choice because of the low levels of saturated fats that is seen in it. Now a new study has revealed that consumption of canola oil could be linked to worsening of memory functions and learning ability in patients with Alzheimer’s disease.

11 Dec 2017

Study finds mechanism of resistance to checkpoint inhibitors and way to reverse it

Researchers have discovered a mechanism of resistance to checkpoint inhibitors and how to reverse it. The biomarker results from the IMvigor210 study are reported at the ESMO Immuno Oncology Congress 2017.

8 Dec 2017

Researchers seek to understand role of novel protein in tumor metastasis

Metastasis, the process in which a tumor spreads to other parts of the body, is responsible for 90% of deaths from tumors. It is the greatest challenge to a cancer patient's survival. Metastatic spread occurs in several steps, these include that tumor cells become mobile and cross into and out of blood vessels.

8 Dec 2017

Study links canola oil consumption with worsened memory, learning ability in Alzheimer's

Canola oil is one of the most widely consumed vegetable oils in the world, yet surprisingly little is known about its effects on health.

7 Dec 2017

Hyperbaric oxygen therapy can improve pathology of Alzheimer's disease, study shows

A new Tel Aviv University study reveals that hyperbaric oxygen treatments may ameliorate symptoms experienced by patients with Alzheimer's disease.

6 Dec 2017

TUM scientists discover emergency shut-off switch for T cell Non-Hodgkin's lymphoma

Safety switches that automatically stop the device for example before it overheats are built into many electrical appliances. Cells are also equipped with such "emergency stop" functions. They make sure that a defective cell doesn't become a tumor cell.

6 Dec 2017

UT Southwestern researchers identify potential approach to suppress lethal parasitic infections

UT Southwestern Medical Center researchers have identified a chemical that suppresses the lethal form of a parasitic infection caused by roundworms that affects up to 100 million people and usually causes only mild symptoms.

5 Dec 2017

Immune-boosting drug combination may hold promise for treating ovarian cancer

Johns Hopkins Kimmel Cancer Center researchers demonstrated that mice with ovarian cancer that received drugs to reactivate dormant genes along with other drugs that activate the immune system had a greater reduction of tumor burden and significantly longer survival than those that received any of the drugs alone.

5 Dec 2017

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

An international team of researchers has shown that a new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease.

5 Dec 2017

Novel drug combination could enhance immunotherapy responses in patients with lung cancer

Johns Hopkins Kimmel Cancer Center researchers and colleagues have identified a novel drug combination therapy that could prime nonsmall cell lung cancers to respond better to immunotherapy.

30 Nov 2017

Study elucidates how lymphocytes regulate immune response after heart attacks

The damage caused by a heart attack triggers an inflammatory reaction which degrades the affected tissue. This response is orchestrated by immune cells that reside in the nearby pericardial adipose tissue, as a study by a team of Ludwig-Maximilians-Universitaet) in Munich shows.

30 Nov 2017

UT Southwestern researchers develop improved gene-editing technique to correct DMD mutations

Regenerative medicine researchers at UT Southwestern Medical Center developed an improved and simplified gene-editing technique using CRISPR/Cas9 tools to correct a common mutation that causes Duchenne muscular dystrophy.

30 Nov 2017

Scientists identify new strategies used by Helicobacter pylori to target mitochondria

Helicobacter pylori is a bacterial pathogen that colonizes the stomach of approximately half of the world's population. Infection with H. pylori is acquired in childhood and lasts for decades.

29 Nov 2017

Study provides potential explanation for increased prevalence of asthma in adult women

In childhood, asthma is more common in boys than girls. But around the time of puberty, that picture reverses. By midlife women are twice as likely as men to have asthma.

29 Nov 2017

Low levels of miR-29 could reduce susceptibility to cardiac fibrosis

Cardiac fibrosis involves an increase of connective tissue in the cardiac muscle, causing a loss of function. A team of researchers at the Technical University of Munich has now discovered that microRNA 29 (miR-29) plays an important role in the formation of tissue fibrosis.

23 Nov 2017

Research findings offer prime drug targets to treat rare liver cancer that strikes young people

After years of rigorous research, a team of scientists has identified the genetic engine that drives a rare form of liver cancer. The findings offer prime targets for drugs to treat the usually lethal disease, fibrolamellar hepatocellular carcinoma (FL-HCC), which mainly strikes adolescents and young adults.

22 Nov 2017

Mouse Model News and Research

Autism treatment: Social impairments can be corrected by brain stimulation

Researchers suggest role for MKL1 protein in development of inflammatory bowel disease

Cellular self-digestion process plays role in development of autoimmune diseases

UQ researchers create new and improved version of ‘love hormone’

Canola oil linked to worsening of Alzheimer’s

Study finds mechanism of resistance to checkpoint inhibitors and way to reverse it

Researchers seek to understand role of novel protein in tumor metastasis

Study links canola oil consumption with worsened memory, learning ability in Alzheimer's

Hyperbaric oxygen therapy can improve pathology of Alzheimer's disease, study shows

TUM scientists discover emergency shut-off switch for T cell Non-Hodgkin's lymphoma

UT Southwestern researchers identify potential approach to suppress lethal parasitic infections

Immune-boosting drug combination may hold promise for treating ovarian cancer

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

Novel drug combination could enhance immunotherapy responses in patients with lung cancer

Study elucidates how lymphocytes regulate immune response after heart attacks

UT Southwestern researchers develop improved gene-editing technique to correct DMD mutations

Scientists identify new strategies used by Helicobacter pylori to target mitochondria

Study provides potential explanation for increased prevalence of asthma in adult women

Low levels of miR-29 could reduce susceptibility to cardiac fibrosis

Research findings offer prime drug targets to treat rare liver cancer that strikes young people

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