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Lack of contraception data could conceal pandemic’s impact on women’s reproductive health

Limited data on the uptake of contraception prior to and during crises such as the Covid-19 pandemic could mean unforeseen issues for sexual and reproductive health services, research from the University of Warwick concludes.

17 Jun 2021

Toxicant profile of BAT's modern oral products is comparable to nicotine replacement therapies

New research published today indicates that BAT's modern oral (MO) products in the form of tobacco-free nicotine pouches have a toxicant profile that is comparable to nicotine replacement therapies (NRTs) and much lower than traditional oral snus, a category of products that, when used as the sole nicotine product is already established as a reduced risk product compared with cigarettes.

17 Jun 2021

Increased viral replication and shedding in nonhuman primates carrying SARS-CoV-2 B.1.1.7 variant

A team of researchers from the US and UK used the AGM intranasal model of SARS-CoV-2 infection to determine differences between a contemporary SARS-CoV-2 D614G variant circulating in summer 2020 and the B.1.1.7 UK variant of concern that emerged in late 2020.

16 Jun 2021

SARS-CoV-2 oral vaccine booster shows promise in animal tests

In a recent study published on the pre-print bioRxiv* server, a group of Israeli researchers discusses their progress towards developing an oral multi-antigen SARS-CoV-2 vaccine.

15 Jun 2021

Lower income and educational levels may correlate with inequalities in seeking dental care

Inequitable access to health care is a pressing global health concern, and care of our teeth is no exception. In fact, the World Health Organization established the Global Goals for Oral Health 2020 in its efforts to help counter socioeconomic-related imbalances.

14 Jun 2021

Robust immunity against SARS-CoV-2 with Pfizer vaccine is mediated by memory B cells

A reassuring study, released as a preprint on the medRxiv* server, from a multi-institutional team of researchers in Italy suggests that with the Pfizer-BioNTech BNT162b2 vaccine, post-vaccination immunity against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is both robust and durable.

14 Jun 2021

SARS-CoV-2 infection detected in a poodle living with a COVID-19 positive family

Researchers in Italy identified a case of reverse zoonosis wherein animals contract the virus from humans. The team detected SARS-CoV-2 in a healthy poodle living with four family members who had COVID-19.

11 Jun 2021

Leaders call for renewed global solidarity to eradicate polio

Today, the Global Polio Eradication Initiative (GPEI) will launch the Polio Eradication Strategy 2022-2026: Delivering on a Promise at a virtual event, to overcome the remaining challenges to ending polio, including setbacks caused by COVID-19.

11 Jun 2021

Largest U.S. study shares first results on effects of COVID-19 on cancer patients

In the largest study of its kind to date, researchers analyzing national data from more than 63,000 patients with cancer and a positive COVID-19 diagnosis report an increased risk of death among those who were older, male, had a higher number of comorbidities, and had hematologic cancers and recent chemotherapy treatments.

11 Jun 2021

Local anesthetic procaine inhibits SARS-CoV-2 in vitro

Research has shown that procaine and procaine-hydrochloride can reduce replication of SARS-CoV-2 and influenza A viruses in infected cells and reduce the production of cytokines by the viruses, making them potentially useful for treating COVID-19.

10 Jun 2021

Childhood stress associated with early emergence of permanent molars

Early in her career neuroscientist Allyson Mackey began thinking about molars. As a researcher who studies brain development, she wanted to know whether when these teeth arrived might indicate early maturation in children.

9 Jun 2021

Researchers review the therapeutic potential of resveratrol nasal formulations in COVID-19

In a recently published article in the journal Frontiers in Immunology, scientists have reviewed the existing literature on antiviral and anti-inflammatory efficacy of resveratrol-based inhaled formulations in preventing SARS-CoV-2 infection and reducing COVID-19 severity.

9 Jun 2021

Youth with a history of foster care have less access to oral health care

According to estimates from the Children's Bureau, an agency within the U.S. Department of Health and Human Services, there were 673,000 children in or entering foster care in the United States in 2019.

9 Jun 2021

Cyperus rotundus medicinal plant shows promise for novel COVID-19 therapeutics

Cyperus rotundus is a plant with a history as herbal medicine, containing many chemical substances frequently found to be drug-like in character: flavonoids, terpenoids, and the like. Compounds sourced from the plant have demonstrated some inhibitory activity against HIV by modulation of the CYP3A4 enzyme, and thus in a drug lead discovery effort, Kumar et al. (July 2021) computationally screened these natural compounds against MPRO in a paper recently published to Computers in Biology and Medicine.

9 Jun 2021

Sleep characteristics associated with cannabis use and binge drinking in teens, young adults

A recent study of teens and young adults found that several factors related to sleep timing and sleep duration are associated with an increased risk of cannabis use and binge drinking of alcohol during the following year.

8 Jun 2021

Study reveals mechanisms by which SGLT2 inhibitors produce renoprotective effect

SGLT2 inhibitors (gliflozins) were developed as oral antidiabetics. They enhance urinary glucose excretion by inhibiting SGLT-2 (sodium-dependent glucose co-transporter-2) in the renal tubuli.

8 Jun 2021

Study reports safety, efficacy of targeted treatment for IgA nephropathy

IgA nephropathy (IgAN) is a chronic kidney disease occurring in young adults and is one of the most common reasons for kidney transplantation in this age group.

7 Jun 2021

Oral antidiabetic medication provides kidney protection in focal segmental glomerulosclerosis

Focal segmental glomerulosclerosis (FSGS) is a rare form of kidney inflammation (glomerulonephritis) in which the glomeruli become increasingly scarred (sclerotic), leading to progressive loss of kidney function.

7 Jun 2021

Redhill Biopharma announces completion of enrollment for oral opaganib phase 2/3 COVID-19 study

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced that it has completed enrollment and randomized the last patient in the global Phase 2/3 study with opaganib (Yeliva, ABC294640) in patients hospitalized with severe COVID-19 pneumonia (NCT04467840).

7 Jun 2021

Potential leptin therapy for nonalcoholic steatohepatitis

In those with fatty liver disease, a person's fat goes to their liver instead of their fat tissue, either because of an absence of fat depots, which is seen in the rare genetic disease lipodystrophy, or because the depots are too full, which is seen in people with obesity.

7 Jun 2021

Oral News and Research

Lack of contraception data could conceal pandemic’s impact on women’s reproductive health

Toxicant profile of BAT's modern oral products is comparable to nicotine replacement therapies

Increased viral replication and shedding in nonhuman primates carrying SARS-CoV-2 B.1.1.7 variant

SARS-CoV-2 oral vaccine booster shows promise in animal tests

Lower income and educational levels may correlate with inequalities in seeking dental care

Robust immunity against SARS-CoV-2 with Pfizer vaccine is mediated by memory B cells

SARS-CoV-2 infection detected in a poodle living with a COVID-19 positive family

Leaders call for renewed global solidarity to eradicate polio

Largest U.S. study shares first results on effects of COVID-19 on cancer patients

Local anesthetic procaine inhibits SARS-CoV-2 in vitro

Childhood stress associated with early emergence of permanent molars

Researchers review the therapeutic potential of resveratrol nasal formulations in COVID-19

Youth with a history of foster care have less access to oral health care

Cyperus rotundus medicinal plant shows promise for novel COVID-19 therapeutics

Sleep characteristics associated with cannabis use and binge drinking in teens, young adults

Study reveals mechanisms by which SGLT2 inhibitors produce renoprotective effect

Study reports safety, efficacy of targeted treatment for IgA nephropathy

Oral antidiabetic medication provides kidney protection in focal segmental glomerulosclerosis

Redhill Biopharma announces completion of enrollment for oral opaganib phase 2/3 COVID-19 study

Potential leptin therapy for nonalcoholic steatohepatitis

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How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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