Pharmaceuticals News and Research

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Study: Angiotensin II can safely improve blood pressure among critically ill patients with hypotension

Sixty years after Cleveland Clinic researchers first isolated the role of angiotensin II in controlling blood pressure, a new international study led by Cleveland Clinic researchers shows that the compound can safely improve blood pressure among critically ill patients who are experiencing life-threatening hypotension, or low blood pressure.

22 May 2017

Scientists to develop drugs for treating cognitive deficits in Huntington's disease sufferers

Scientists at the University of Sussex have started work on a multi-million pound project to develop drugs to treat the debilitating loss of cognitive function associated with Huntington's disease.

19 May 2017

Research into cellular senescence may lead to new ways of treating age-related disorders

One of the things that happens to our bodies as we age is that certain cells start to accumulate. So-called senescent cells – cells that "retire" and stop dividing but refuse to die – are always present, and they even serve some important functions, such as in wound repair.

18 May 2017

FDA-approved drug improves clinical outcomes among patients with rare immunologic disease

Adding the injectable drug mepolizumab to standard treatment for eosinophilic granulomatosis with polyangiitis (EGPA), a rare immunologic disease, significantly improved clinical outcomes among participants in an advanced clinical trial, scientists report.

18 May 2017

Seventh Wave announces collaboration with Yecuris to study new liver disease therapies

Seventh Wave Laboratories, a consulting-based contract research organization that assesses the safety and efficacy of pharmaceutical products and medical devices, has announced an exclusive collaboration with Yecuris Corporation, a global leader in the development and use of humanized models in drug development research.

18 May 2017

Nemaura Pharma device addresses needle phobia in diabetics

Results of recent clinical trials carried out on type 1 diabetics by Nemaura Pharma using its Memspatch Insulin Micro-needle Device (IMD) will come as a relief to those who fear needles and injections, a condition medically known as trypanophobia, affecting 10 percent of the world’s population.

18 May 2017

FDA expands approval for cystic fibrosis drug to treat additional rare gene mutations

The U.S. Food and Drug Administration today expanded the approved use of Kalydeco (ivacaftor) for treating cystic fibrosis.

18 May 2017

Microbes can manipulate molecular machinery of host cells to influence health

All animals -- from sea sponges to modern-day humans -- evolved in a world already teeming with microbes. These single-celled microorganisms now cover practically every surface of our bodies and are as much a part of our biology as our own tissues and organs.

17 May 2017

Scientists use AHDS patients’ cells to recreate disease and mimic blood-brain barrier

The blood-brain barrier is biology's proverbial double-edged sword. An impermeable shield of endothelial cells that protects our brains from toxins and other threats that may lurk in circulating blood, the barrier can also exclude therapeutic drugs and, at times, essential biomolecules required for healthy brain development.

17 May 2017

Researchers develop safe and easy self-donning surgical gowns

In the health care setting, there is an increasing need for a self-donning surgical gown that health care personnel can don without the need for any assistance.

17 May 2017

EPFL scientists develop new antibody-linked biosensor to track drug concentration in the blood

Being able to monitor drug concentration in the blood of a patient is an important aspect of any pharmaceutical treatment. However, this requires equipment and facilities that are often missing from field healthcare in developing countries, but also inhibits the quality of life for patients elsewhere.

16 May 2017

WSU scientists develop new approach to deliver therapeutics to tumors

For the first time, WSU researchers have demonstrated a way to deliver a drug to a tumor by attaching it to a blood cell. The innovation could let doctors target tumors with anticancer drugs that might otherwise damage healthy tissues.

16 May 2017

IBM scientists identify new way to trigger the body's immune response to fight diseases

IBM announced its researchers have identified a new way to trigger the body's immune response by using polymer-coated graphene sheets. The research was recently published in Nature Communications.

16 May 2017

COSMIC'S new 3D system can help identify and characterize cancer drug targets

COSMIC-3D, the most comprehensive system for exploring cancer mutations in three dimensions, is launched today by COSMIC, based at the Wellcome Trust Sanger Institute, in collaboration with Astex Pharmaceuticals, Cambridge, UK.

15 May 2017

Research findings provide insight into mechanisms underlying differences in efficacy of anti-TNF drugs

Osaka University-led researchers identified differences in how three drugs bind to tumor necrosis factor, a key mediator of inflammatory disease. The team used sedimentation velocity analytical ultracentrifugation to investigate drug-target binding in a physiological environment and at clinically-relevant concentrations.

15 May 2017

Phase 1 clinical studies reveal safety, tolerability of therapeutic vaccine in celiac disease patients

ImmusanT, Inc., a clinical-stage company developing Nexvax2, a therapeutic vaccine intended to protect against the effects of gluten exposure while maintaining a gluten-free diet in HLA-DQ2.5+ patients with celiac disease, today announced the publication of positive data from two Phase 1 clinical trials of Nexvax2 in celiac disease.

12 May 2017

New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

The first drug using spherical nucleic acids to be systemically given to humans has been developed by Northwestern University scientists and approved by the Food and Drug Administration as an investigational new drug for an early-stage clinical trial in the deadly brain cancer glioblastoma multiforme.

12 May 2017

Researchers discover dual-functional compound that shows potential to combat type 1, type 2 diabetes

According to research published online in The FASEB Journal, scientists have discovered a dual peptide called "PGLP-1" that promotes insulin secretion and inhibits gluconeogenesis.

11 May 2017

Boosting clinical trial research in London

Richmond Pharmacology have opened their fourth clinical trial facility and the new site has been used for this type of work for more than 30 years. It's in an ideal location embedded in the University and teaching hospital campus.

11 May 2017

New 3D printing technology may offer quicker implantation of better medical devices for millions

For the millions of people every year who have or need medical devices implanted, a new advancement in 3D printing technology developed at the University of Florida promises significantly quicker implantation of devices that are stronger, less expensive, more flexible and more comfortable than anything currently available.

11 May 2017

Pharmaceuticals News and Research

Study: Angiotensin II can safely improve blood pressure among critically ill patients with hypotension

Scientists to develop drugs for treating cognitive deficits in Huntington's disease sufferers

Research into cellular senescence may lead to new ways of treating age-related disorders

FDA-approved drug improves clinical outcomes among patients with rare immunologic disease

Seventh Wave announces collaboration with Yecuris to study new liver disease therapies

Nemaura Pharma device addresses needle phobia in diabetics

FDA expands approval for cystic fibrosis drug to treat additional rare gene mutations

Microbes can manipulate molecular machinery of host cells to influence health

Scientists use AHDS patients’ cells to recreate disease and mimic blood-brain barrier

Researchers develop safe and easy self-donning surgical gowns

EPFL scientists develop new antibody-linked biosensor to track drug concentration in the blood

WSU scientists develop new approach to deliver therapeutics to tumors

IBM scientists identify new way to trigger the body's immune response to fight diseases

COSMIC'S new 3D system can help identify and characterize cancer drug targets

Research findings provide insight into mechanisms underlying differences in efficacy of anti-TNF drugs

Phase 1 clinical studies reveal safety, tolerability of therapeutic vaccine in celiac disease patients

New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

Researchers discover dual-functional compound that shows potential to combat type 1, type 2 diabetes

Boosting clinical trial research in London

New 3D printing technology may offer quicker implantation of better medical devices for millions

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