Respiratory News and Research

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Previously unknown mechanisms may lead to new approaches to fight viral infections

Viruses like influenza A and Ebola invade human cells in a number of steps. In an interdisciplinary approach, research teams from Heidelberg University and Heidelberg University Hospital investigated the final stages of viral penetration using electron tomography and computer simulations.

25 Apr 2023

Colchicine therapy benefits pediatric long COVID patients suffering from recurring fever

Researchers at National Jewish Health found that a subset of children suffering recurring fevers as a result of long COVID-19, benefited from a daily medication treatment commonly used for gout and periodic fever syndrome.

25 Apr 2023

Young kids with common ENT problems may be at subsequent risk of autism

Young children with common ear, nose, and throat (ENT) issues may be at subsequent risk of autism or high levels of demonstrable autism traits, suggests research published online in the open access journal BMJ Open.

25 Apr 2023

T cell-mediated recognition of conserved bacterial epitope generates broad immunity

Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity.

25 Apr 2023

Prenatal exposure to cannabinoids linked to newborn mortality and respiratory problems

Consumption of cannabis (marijuana) or derivatives during pregnancy can cause respiratory problems for the baby, such as impaired control of breathing and diminished sensitivity to carbon dioxide, both of which favor sudden infant death syndrome.

25 Apr 2023

High-protein diet counters adaptive thermogenesis in prediabetic individuals

Study investigated whether an increased protein/carbohydrate ratio would reduce adaptive thermogenesis (AT) and the expected positive energy balance (EB) during weight maintenance after weight loss in participants with prediabetes in the postobese state.

24 Apr 2023

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

Research investigates the susceptibility of seven bat species to SARS-CoV-2 by expressing their ACE2 receptor in a non-permissive avian cell line. The study found that all seven bat species were susceptible to SARS-CoV-2, but the level of virus replication differed between bat species and virus variants.

24 Apr 2023

RSV infection in the first year of life associated with increased risk of childhood asthma

Severe respiratory syncytial virus (RSV) infection has long been associated with the onset of childhood wheezing diseases, but the relationship between RSV infection during infancy and the development of childhood asthma has remained unclear.

24 Apr 2023

What are the trends in severe outcomes among patients hospitalized with COVID-19 during the first 2 years of the COVID-19 pandemic?

Researchers documented surveillance across a network of 155 acute care hospitals in Canada between March 15, 2020, and May 28, 2022.

24 Apr 2023

Study identifies an unknown SARS-CoV-2 lineage on three mink farms in Poland

Researchers detected a cryptic severe acute respiratory syndrome coronavirus 2 lineage on mink farms in Poland.

24 Apr 2023

What are the frequency and risk of adverse events developing in patients with epilepsy who are using CBD?

Researchers evaluated epilepsy patients to evaluate cannabidiol use-related adverse events.

24 Apr 2023

Deciphering immunological imprinting in the context of COVID-19

In a recent article published in the journal Immunity, researchers explained the concept of immunological imprinting and its underlying principles. They also discussed its potential role in the context of coronavirus disease 2019 (COVID-19) vaccines.

24 Apr 2023

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

A self-amplifying replicon RNA vaccine against SARS-CoV-2 can elicit durable and protective immunity in pigtail macaques, even after neutralizing antibody responses have waned to undetectable levels.

23 Apr 2023

Study reveals alarming global burden of antimicrobial resistance in bacterial infections

The paper presents a systematic analysis of the global burden of bacterial antimicrobial resistance in 2019. The authors highlight the urgent need for action to address this growing public health threat.

23 Apr 2023

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

CMPK2 identified as a potential pan-flavivirus inhibitor, restricting virus replication and providing a basis for developing new antiviral treatments.

23 Apr 2023

Is there an association between post COVID-19 syndrome and cognitive impairment?

Researchers examined the cognitive characteristics of patients with post-coronavirus disease 2019 syndrome.

21 Apr 2023

An exploration of the pathophysiological factors and abnormalities of coagulation of long-COVID

Researchers explored the pathophysiological variables and coagulation abnormalities associated with long coronavirus disease (COVID).

21 Apr 2023

Omicron spike N679K mutation acts as a loss-of-function mutation attenuating SARS-CoV-2 in vitro & in vivo

Researchers explored the impact of a loss-of-function mutation in the SARS-CoV-2 Omicron variants on the expression of the spike protein.

20 Apr 2023

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

Researchers explored the protective systemic and mucosal immunity provided by a single dose of a live-attenuated SARS-CoV-2 vaccine candidate.

20 Apr 2023

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Researchers explored increasing replicative fitness of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants

20 Apr 2023

Respiratory News and Research

Previously unknown mechanisms may lead to new approaches to fight viral infections

Colchicine therapy benefits pediatric long COVID patients suffering from recurring fever

Young kids with common ENT problems may be at subsequent risk of autism

T cell-mediated recognition of conserved bacterial epitope generates broad immunity

Prenatal exposure to cannabinoids linked to newborn mortality and respiratory problems

High-protein diet counters adaptive thermogenesis in prediabetic individuals

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

RSV infection in the first year of life associated with increased risk of childhood asthma

What are the trends in severe outcomes among patients hospitalized with COVID-19 during the first 2 years of the COVID-19 pandemic?

Study identifies an unknown SARS-CoV-2 lineage on three mink farms in Poland

What are the frequency and risk of adverse events developing in patients with epilepsy who are using CBD?

Deciphering immunological imprinting in the context of COVID-19

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

Study reveals alarming global burden of antimicrobial resistance in bacterial infections

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

Is there an association between post COVID-19 syndrome and cognitive impairment?

An exploration of the pathophysiological factors and abnormalities of coagulation of long-COVID

Omicron spike N679K mutation acts as a loss-of-function mutation attenuating SARS-CoV-2 in vitro & in vivo

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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